Why, when and how to assess ischemia and viability in patients with chronic total occlusions

Anna van Veelen; Stefan P. Schumacher; Wynand J. Stuijfzand; José P S Henriques; Paul Knaapen; Wijnand J. A. Stuijfzand

doi:10.1007/978-3-031-05437-2_4

Why, when and how to assess ischemia and viability in patients with chronic total occlusions

Anna van Veelen
, Stefan P. Schumacher
, Wynand J. Stuijfzand
, José P S Henriques
, Paul Knaapen^*
, Wijnand J. A. Stuijfzand

^*Corresponding author for this work

Department of Cardiology, Amsterdam UMC, VU Medical Center
Vrije Universiteit Amsterdam
Amsterdam UMC - Vrije Universiteit Amsterdam
Department of Cardiology, Academic Medical Center, University of Amsterdam
University of Amsterdam
Department of Cardiology, Amsterdam UMC, location AMC, Amsterdam, The Netherlands.

Research output: Chapter in Book/Report/Conference proceeding › Chapter › Academic › peer-review

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Abstract

Currently, international guidelines recommend the evaluation of ischemic symptoms, as well as the extent of ischemia and the presence of viability, prior to referring patients with stable coronary artery disease, including chronic total occlusion (CTO), for revascularization. A few randomized trials and numerous observational studies have tried to determine the value of ischemia-driven and viability-driven revascularization, but demonstrated contradicting findings. The present review will focus on the current knowledge regarding ischemia and viability testing in patients with a CTO. The evidence and rationale to assess ischemia and viability, next to the clinical workup for CTO revascularization in clinical practice, will be discussed. In addition, an overview of available noninvasive imaging modalities to assess the presence and extent of ischemia and viability will be provided.

Original language	English
Title of host publication	Percutaneous Coronary Intervention for Chronic Total Occlusion
Subtitle of host publication	The Hybrid Approach
Place of Publication	Cham
Publisher	Springer International Publishing
Chapter	4
Pages	27-42
Number of pages	16
Edition	2
ISBN (Electronic)	9783031054372
ISBN (Print)	9783031054365
DOIs	https://doi.org/10.1007/978-3-031-05437-2_4
Publication status	Published - 23 Nov 2022

Publication series

Name	Percutaneous Coronary Intervention for Chronic Total Occlusion: The Hybrid Approach

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

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10.1007/978-3-031-05437-2_4

Why-when-and-how-to-assess-ischemia-and-viability-in-patients-with-chronic-total-occlusions.pdfFinal published version, 34.8 MBLicence: Taverne

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van Veelen, A., Schumacher, S. P., Stuijfzand, W. J., Henriques, J. P. S., Knaapen, P., & Stuijfzand, W. J. A. (2022). Why, when and how to assess ischemia and viability in patients with chronic total occlusions. In Percutaneous Coronary Intervention for Chronic Total Occlusion: The Hybrid Approach (2 ed., pp. 27-42). (Percutaneous Coronary Intervention for Chronic Total Occlusion: The Hybrid Approach). Springer International Publishing. https://doi.org/10.1007/978-3-031-05437-2_4

van Veelen, Anna ; Schumacher, Stefan P. ; Stuijfzand, Wynand J. et al. / Why, when and how to assess ischemia and viability in patients with chronic total occlusions. Percutaneous Coronary Intervention for Chronic Total Occlusion: The Hybrid Approach. 2. ed. Cham : Springer International Publishing, 2022. pp. 27-42 (Percutaneous Coronary Intervention for Chronic Total Occlusion: The Hybrid Approach).

@inbook{3239192e0ef3442f8130ddc8b5a630a6,

title = "Why, when and how to assess ischemia and viability in patients with chronic total occlusions",

abstract = "Currently, international guidelines recommend the evaluation of ischemic symptoms, as well as the extent of ischemia and the presence of viability, prior to referring patients with stable coronary artery disease, including chronic total occlusion (CTO), for revascularization. A few randomized trials and numerous observational studies have tried to determine the value of ischemia-driven and viability-driven revascularization, but demonstrated contradicting findings. The present review will focus on the current knowledge regarding ischemia and viability testing in patients with a CTO. The evidence and rationale to assess ischemia and viability, next to the clinical workup for CTO revascularization in clinical practice, will be discussed. In addition, an overview of available noninvasive imaging modalities to assess the presence and extent of ischemia and viability will be provided.",

author = "\{van Veelen\}, Anna and Schumacher, \{Stefan P.\} and Stuijfzand, \{Wynand J.\} and Henriques, \{Jos{\'e} P S\} and Paul Knaapen and Stuijfzand, \{Wijnand J. A.\}",

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language = "English",

isbn = "9783031054365",

series = "Percutaneous Coronary Intervention for Chronic Total Occlusion: The Hybrid Approach",

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van Veelen, A, Schumacher, SP, Stuijfzand, WJ, Henriques, JPS , Knaapen, P & Stuijfzand, WJA 2022, Why, when and how to assess ischemia and viability in patients with chronic total occlusions. in Percutaneous Coronary Intervention for Chronic Total Occlusion: The Hybrid Approach. 2 edn, Percutaneous Coronary Intervention for Chronic Total Occlusion: The Hybrid Approach, Springer International Publishing, Cham, pp. 27-42. https://doi.org/10.1007/978-3-031-05437-2_4

Why, when and how to assess ischemia and viability in patients with chronic total occlusions. / van Veelen, Anna; Schumacher, Stefan P.; Stuijfzand, Wynand J. et al.
Percutaneous Coronary Intervention for Chronic Total Occlusion: The Hybrid Approach. 2. ed. Cham: Springer International Publishing, 2022. p. 27-42 (Percutaneous Coronary Intervention for Chronic Total Occlusion: The Hybrid Approach).

Research output: Chapter in Book/Report/Conference proceeding › Chapter › Academic › peer-review

TY - CHAP

T1 - Why, when and how to assess ischemia and viability in patients with chronic total occlusions

AU - van Veelen, Anna

AU - Schumacher, Stefan P.

AU - Stuijfzand, Wynand J.

AU - Henriques, José P S

AU - Knaapen, Paul

AU - Stuijfzand, Wijnand J. A.

PY - 2022/11/23

Y1 - 2022/11/23

N2 - Currently, international guidelines recommend the evaluation of ischemic symptoms, as well as the extent of ischemia and the presence of viability, prior to referring patients with stable coronary artery disease, including chronic total occlusion (CTO), for revascularization. A few randomized trials and numerous observational studies have tried to determine the value of ischemia-driven and viability-driven revascularization, but demonstrated contradicting findings. The present review will focus on the current knowledge regarding ischemia and viability testing in patients with a CTO. The evidence and rationale to assess ischemia and viability, next to the clinical workup for CTO revascularization in clinical practice, will be discussed. In addition, an overview of available noninvasive imaging modalities to assess the presence and extent of ischemia and viability will be provided.

AB - Currently, international guidelines recommend the evaluation of ischemic symptoms, as well as the extent of ischemia and the presence of viability, prior to referring patients with stable coronary artery disease, including chronic total occlusion (CTO), for revascularization. A few randomized trials and numerous observational studies have tried to determine the value of ischemia-driven and viability-driven revascularization, but demonstrated contradicting findings. The present review will focus on the current knowledge regarding ischemia and viability testing in patients with a CTO. The evidence and rationale to assess ischemia and viability, next to the clinical workup for CTO revascularization in clinical practice, will be discussed. In addition, an overview of available noninvasive imaging modalities to assess the presence and extent of ischemia and viability will be provided.

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van Veelen A, Schumacher SP, Stuijfzand WJ, Henriques JPS , Knaapen P , Stuijfzand WJA. Why, when and how to assess ischemia and viability in patients with chronic total occlusions. In Percutaneous Coronary Intervention for Chronic Total Occlusion: The Hybrid Approach. 2 ed. Cham: Springer International Publishing. 2022. p. 27-42. (Percutaneous Coronary Intervention for Chronic Total Occlusion: The Hybrid Approach). doi: 10.1007/978-3-031-05437-2_4

Why, when and how to assess ischemia and viability in patients with chronic total occlusions

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UN SDGs

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