Which trials do we need? A pragmatic randomized controlled trial on the duration of antibiotic therapy after debridement of midfoot region: fixed duration versus personalized approach

Erlangga Yusuf; Johan van Laethem; Jorg L. de Bruin; Sander Ten Raa; Maya Hites; Edgar J. G. Peters

doi:10.1016/j.cmi.2025.06.006

Which trials do we need? A pragmatic randomized controlled trial on the duration of antibiotic therapy after debridement of midfoot region: fixed duration versus personalized approach

Erlangga Yusuf^*
, Johan van Laethem
, Jorg L. de Bruin
, Sander Ten Raa
, Maya Hites
, Edgar J. G. Peters

^*Corresponding author for this work

Erasmus University Rotterdam
Vrije Universiteit Brussel
Université libre de Bruxelles
Vrije Universiteit Amsterdam
Amsterdam UMC

Research output: Contribution to journal › Comment/Letter to the editor › Academic

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Original language	English
Pages (from-to)	1951-1953
Number of pages	3
Journal	Clinical Microbiology and Infection
Volume	31
Issue number	12
Early online date	2025
DOIs	https://doi.org/10.1016/j.cmi.2025.06.006
Publication status	Published - Dec 2025

Keywords

Clinical trial
Diabetic foot infection
Duration antimicrobial therapy
Osteomyelitis
Skin soft tissue infection

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10.1016/j.cmi.2025.06.006

Which-trials-do-we-need-a-pragmatic-randomized-controlled-trial-on-the-duration-of-antibiotic-therapy-after-debridement.pdfFinal published version, 393 KBLicence: Taverne

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Yusuf, E., van Laethem, J., de Bruin, J. L., Raa, S. T., Hites, M., & Peters, E. J. G. (2025). Which trials do we need? A pragmatic randomized controlled trial on the duration of antibiotic therapy after debridement of midfoot region: fixed duration versus personalized approach. Clinical Microbiology and Infection, 31(12), 1951-1953. https://doi.org/10.1016/j.cmi.2025.06.006

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title = "Which trials do we need? A pragmatic randomized controlled trial on the duration of antibiotic therapy after debridement of midfoot region: fixed duration versus personalized approach",

keywords = "Clinical trial, Diabetic foot infection, Duration antimicrobial therapy, Osteomyelitis, Skin soft tissue infection",

author = "Erlangga Yusuf and \{van Laethem\}, Johan and \{de Bruin\}, \{Jorg L.\} and Raa, \{Sander Ten\} and Maya Hites and Peters, \{Edgar J. G.\}",

year = "2025",

month = dec,

doi = "10.1016/j.cmi.2025.06.006",

language = "English",

volume = "31",

pages = "1951--1953",

journal = "Clinical Microbiology and Infection",

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Yusuf, E, van Laethem, J, de Bruin, JL, Raa, ST, Hites, M & Peters, EJG 2025, 'Which trials do we need? A pragmatic randomized controlled trial on the duration of antibiotic therapy after debridement of midfoot region: fixed duration versus personalized approach', Clinical Microbiology and Infection, vol. 31, no. 12, pp. 1951-1953. https://doi.org/10.1016/j.cmi.2025.06.006

Which trials do we need? A pragmatic randomized controlled trial on the duration of antibiotic therapy after debridement of midfoot region: fixed duration versus personalized approach. / Yusuf, Erlangga; van Laethem, Johan; de Bruin, Jorg L. et al.
In: Clinical Microbiology and Infection, Vol. 31, No. 12, 12.2025, p. 1951-1953.

Research output: Contribution to journal › Comment/Letter to the editor › Academic

TY - JOUR

T1 - Which trials do we need? A pragmatic randomized controlled trial on the duration of antibiotic therapy after debridement of midfoot region

T2 - fixed duration versus personalized approach

AU - Yusuf, Erlangga

AU - van Laethem, Johan

AU - de Bruin, Jorg L.

AU - Raa, Sander Ten

AU - Hites, Maya

AU - Peters, Edgar J. G.

PY - 2025/12

Y1 - 2025/12

KW - Clinical trial

KW - Diabetic foot infection

KW - Duration antimicrobial therapy

KW - Osteomyelitis

KW - Skin soft tissue infection

UR - https://www.scopus.com/pages/publications/105009887353

U2 - 10.1016/j.cmi.2025.06.006

DO - 10.1016/j.cmi.2025.06.006

M3 - Comment/Letter to the editor

C2 - 40513828

SN - 1198-743X

VL - 31

SP - 1951

EP - 1953

JO - Clinical Microbiology and Infection

JF - Clinical Microbiology and Infection

IS - 12

ER -

Which trials do we need? A pragmatic randomized controlled trial on the duration of antibiotic therapy after debridement of midfoot region: fixed duration versus personalized approach

Keywords

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