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Visual inspection of MR relative cerebral blood volume maps has limited value for distinguishing progression from pseudoprogression in glioblastoma multiforme patients

  • Melissa Kerkhof
  • , Pauline L. Tans
  • , Rogier E. Hagenbeek
  • , Geert J. Lycklama À Nijeholt
  • , Finn K. Holla
  • , Tjeerd J. Postma
  • , Chiara S. Straathof
  • , Linda Dirven
  • , Martin Jb Taphoorn
  • , Maaike J. Vos
  • Department of Neurology, 2501 CK The Hague, Netherlands
  • Department of Radiology, 2501 CK The Hague, Netherlands
  • Leiden University

Research output: Contribution to journalArticleAcademicpeer-review

Abstract

AIM: We examined whether visual interpretation of relative cerebral blood volume (rCBV) color maps made with dynamic susceptibility-weighted perfusion MRI can reliably distinguish progressive disease (PD) from pseudoprogression (PsPD) in glioblastoma patients during treatment with temozolomide chemoradiation.
Original languageEnglish
Pages (from-to)297-306
JournalCNS oncology
Volume6
Issue number4
DOIs
Publication statusPublished - 2017

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