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Vaginal microbiota and mucosal HIV-1 transmission

Research output: PhD ThesisPhd-Thesis - Research and graduation internal

Abstract

This thesis aimed to unravel the unique immune mechanisms in vaginal mucosa. We developed and validated a primary human vaginal tissue model that allowed us to study the most relevant immune cells during dysbiosis of the vaginal microbiome and HIV-1 transmission in people assigned female at birth.
Key findings include that Prevotella timonensis, a bacterium associated with
Original languageEnglish
QualificationDoctor of Philosophy
Awarding Institution
  • University of Amsterdam
Supervisors/Advisors
  • Geijtenbeek, Teunis, Supervisor
  • van Leeuwen, Elisabeth, Co-supervisor
  • Ribeiro, Carla, Co-supervisor
Award date30 Jan 2025
Publication statusPublished - 2025

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

  1. SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well-being
  2. SDG 5 - Gender Equality
    SDG 5 Gender Equality

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