Unmet clinical need in autoimmune liver diseases

Jessica K. Dyson; Gwilym Webb; Gideon M. Hirschfield; Ansgar Lohse; Ulrich Beuers; Keith Lindor; David E. J. Jones

doi:10.1016/j.jhep.2014.09.010

Unmet clinical need in autoimmune liver diseases

Jessica K. Dyson
, Gwilym Webb
, Gideon M. Hirschfield
, Ansgar Lohse
, Ulrich Beuers
, Keith Lindor
, David E. J. Jones

Research output: Contribution to journal › Review article › Academic › peer-review

Abstract

Despite recent advances in understanding and treatment, there remain significant areas of unmet clinical need in each of the autoimmune liver diseases (AILDs). The evolving research landscape and emerging large patient cohorts are creating unique opportunities to translate science into new therapies and care pathways, with the potential to significantly improve the lives of AILD patients. However, the areas of unmet need represent real challenges, which need to be addressed, if this vision is to be realised. This review describes the areas of unmet need in AILD in adults relating to diagnostic and prognostic assessment, primary therapy, symptom management, trial design and delivery, and structured care delivery, with the aim of focusing future research prioritisation

Original language	English
Pages (from-to)	208-218
Journal	Journal of hepatology
Volume	62
Issue number	1
DOIs	https://doi.org/10.1016/j.jhep.2014.09.010
Publication status	Published - 2015

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

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10.1016/j.jhep.2014.09.010

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title = "Unmet clinical need in autoimmune liver diseases",

abstract = "Despite recent advances in understanding and treatment, there remain significant areas of unmet clinical need in each of the autoimmune liver diseases (AILDs). The evolving research landscape and emerging large patient cohorts are creating unique opportunities to translate science into new therapies and care pathways, with the potential to significantly improve the lives of AILD patients. However, the areas of unmet need represent real challenges, which need to be addressed, if this vision is to be realised. This review describes the areas of unmet need in AILD in adults relating to diagnostic and prognostic assessment, primary therapy, symptom management, trial design and delivery, and structured care delivery, with the aim of focusing future research prioritisation",

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doi = "10.1016/j.jhep.2014.09.010",

language = "English",

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AU - Dyson, Jessica K.

AU - Webb, Gwilym

AU - Hirschfield, Gideon M.

AU - Lohse, Ansgar

AU - Beuers, Ulrich

AU - Lindor, Keith

AU - Jones, David E. J.

PY - 2015

Y1 - 2015

N2 - Despite recent advances in understanding and treatment, there remain significant areas of unmet clinical need in each of the autoimmune liver diseases (AILDs). The evolving research landscape and emerging large patient cohorts are creating unique opportunities to translate science into new therapies and care pathways, with the potential to significantly improve the lives of AILD patients. However, the areas of unmet need represent real challenges, which need to be addressed, if this vision is to be realised. This review describes the areas of unmet need in AILD in adults relating to diagnostic and prognostic assessment, primary therapy, symptom management, trial design and delivery, and structured care delivery, with the aim of focusing future research prioritisation

AB - Despite recent advances in understanding and treatment, there remain significant areas of unmet clinical need in each of the autoimmune liver diseases (AILDs). The evolving research landscape and emerging large patient cohorts are creating unique opportunities to translate science into new therapies and care pathways, with the potential to significantly improve the lives of AILD patients. However, the areas of unmet need represent real challenges, which need to be addressed, if this vision is to be realised. This review describes the areas of unmet need in AILD in adults relating to diagnostic and prognostic assessment, primary therapy, symptom management, trial design and delivery, and structured care delivery, with the aim of focusing future research prioritisation

U2 - 10.1016/j.jhep.2014.09.010

DO - 10.1016/j.jhep.2014.09.010

M3 - Review article

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SP - 208

EP - 218

JO - Journal of hepatology

JF - Journal of hepatology

IS - 1

ER -

Unmet clinical need in autoimmune liver diseases

Abstract

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