TY - JOUR
T1 - Undifferentiated connective tissue disease: State of the art on clinical practice guidelines
AU - Antunes, Margarida
AU - Scirè, Carlo Alberto
AU - Talarico, Rosaria
AU - Alexander, Tobias
AU - Avcin, Tadej
AU - Belocchi, Chiara
AU - Doria, Andrea
AU - Franceschini, Franco
AU - Galetti, Ilaria
AU - Govoni, Marcello
AU - Hachulla, Eric
AU - Launay, David
AU - Lepri, Gemma
AU - Macieira, Carla
AU - Matucci-Cerinic, Marco
AU - Montecucco, Carlo Maurizio
AU - Moraes-Fontes, Maria Francisca
AU - Mouthon, Luc
AU - Paolino, Sabrina
AU - Ramoni, Veronique
AU - Tani, Chiara
AU - Tas, Sander W.
AU - Tincani, Angela
AU - van Vollenhoven, Ronald
AU - Zen, Margherita
AU - Fonseca, Joao
AU - Bombardieri, Stefano
AU - Fonseca, João Eurico
AU - Schneider, Matthias
AU - Smith, Vanessa
AU - Cutolo, Maurizio
AU - Mosca, Marta
AU - Beretta, Lorenzo
PY - 2019/2/1
Y1 - 2019/2/1
N2 - The term a € undifferentiated connective tissue disease' (UCTD) is generally used to describe clinical entities characterised by clinical and serological manifestations of systemic autoimmune diseases but not fulfilling the criteria for defined connective tissue diseases (CTDs). In this narrative review, we summarise the results of a systematic literature research, which was performed as part of the ERN ReCONNET project, aimed at evaluating existing clinical practice guidelines (CPGs) or recommendations. No specific CPG on UCTD were found, potential areas of intervention are absence of a consensus definition of UCTD, need for specific monitoring and therapeutic protocols, stratification of UCTD based on the risk of developing a defined CTD and preventive measure for the future development of a more severe condition. Patients feel uncertainty regarding the name of the disease and feel the need of a better education and understanding of these conditions and its possible changes over time.
AB - The term a € undifferentiated connective tissue disease' (UCTD) is generally used to describe clinical entities characterised by clinical and serological manifestations of systemic autoimmune diseases but not fulfilling the criteria for defined connective tissue diseases (CTDs). In this narrative review, we summarise the results of a systematic literature research, which was performed as part of the ERN ReCONNET project, aimed at evaluating existing clinical practice guidelines (CPGs) or recommendations. No specific CPG on UCTD were found, potential areas of intervention are absence of a consensus definition of UCTD, need for specific monitoring and therapeutic protocols, stratification of UCTD based on the risk of developing a defined CTD and preventive measure for the future development of a more severe condition. Patients feel uncertainty regarding the name of the disease and feel the need of a better education and understanding of these conditions and its possible changes over time.
UR - https://www.scopus.com/pages/publications/85062412386
UR - https://www.ncbi.nlm.nih.gov/pubmed/30886731
U2 - 10.1136/rmdopen-2018-000786
DO - 10.1136/rmdopen-2018-000786
M3 - Review article
C2 - 30886731
SN - 2056-5933
VL - 4
SP - e000786
JO - RMD open
JF - RMD open
IS - Suppl 1
M1 - e000786
ER -