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Uncoupling anaphase-promoting complex/cyclosome activity from spindle assembly checkpoint control by deregulating polo-like kinase 1

  • Barbara C.M. Van De Weerdt
  • , Marcel A.T.M. Van Vugt
  • , Catherine Lindon
  • , Jos J.W. Kauw
  • , Marieke J. Rozendaal
  • , Rob Klompmaker
  • , Rob M.F. Wolthuis
  • , René H. Medema*
  • *Corresponding author for this work
  • Division of Molecular Biology/P2
  • Netherlands Cancer Institute
  • Cancer Research UK
  • Department of Medical Oncology
  • Utrecht University

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Biochemistry, Genetics and Molecular Biology