Type 2-low asthma phenotypes by integration of sputum transcriptomics and serum proteomics

Nazanin Zounemat Kermani; Mansoor Saqi; Paul Agapow; Stelios Pavlidis; Chihhsi Kuo; Kai Sen Tan; Sharon Mumby; Kai Sun; Matthew Loza; Frederic Baribaud; Ana R. Sousa; John Riley; Asa M. Wheelock; Craig E. Wheelock; Bertrand de Meulder; Jim Schofield; Stephany Sánchez-Ovando; Jodie Louise Simpson; Katherine Joanne Baines; Peter A. Wark; Charles Auffray; Sven-Erik Dahlen; Peter J. Sterk; Ratko Djukanovic; Ian M. Adcock; Yi-ke Guo; Kian Fan Chung

doi:10.1111/all.14573

Type 2-low asthma phenotypes by integration of sputum transcriptomics and serum proteomics

Nazanin Zounemat Kermani
, Mansoor Saqi
, Paul Agapow
, Stelios Pavlidis
, Chihhsi Kuo
, Kai Sen Tan
, Sharon Mumby
, Kai Sun
, Matthew Loza
, Frederic Baribaud
, Ana R. Sousa
, John Riley
, Asa M. Wheelock
, Craig E. Wheelock
, Bertrand de Meulder
, Jim Schofield
, Stephany Sánchez-Ovando
, Jodie Louise Simpson
, Katherine Joanne Baines
, Peter A. Wark

Charles Auffray, Sven-Erik Dahlen, Peter J. Sterk, Ratko Djukanovic, Ian M. Adcock, Yi-ke Guo, Kian Fan Chung^*

^*Corresponding author for this work

Affiliatie UvA

Imperial College London
National University of Singapore
Johnson & Johnson
GlaxoSmithKline
Karolinska Institutet
Universite Claude Bernard Lyon 1
University of Southampton
University Hospital Southampton NHS Foundation Trust
University of Newcastle

Research output: Contribution to journal › Comment/Letter to the editor › Academic

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Original language	English
Pages (from-to)	380-383
Number of pages	4
Journal	Allergy: European Journal of Allergy and Clinical Immunology
Volume	76
Issue number	1
Early online date	2020
DOIs	https://doi.org/10.1111/all.14573
Publication status	Published - Jan 2021

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

asthma
bioinformatics
endotypes
precision medicine
systems biology

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10.1111/all.14573

Type-2-low-asthma-phenotypes-by-integration-of-sputum-transcriptomics-and-serum-proteomics.pdfFinal published version, 596 KBLicence: Taverne

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Zounemat Kermani, N., Saqi, M., Agapow, P., Pavlidis, S., Kuo, C., Tan, K. S., Mumby, S., Sun, K., Loza, M., Baribaud, F., Sousa, A. R., Riley, J., Wheelock, A. M., Wheelock, C. E., de Meulder, B., Schofield, J., Sánchez-Ovando, S., Simpson, J. L., Baines, K. J., ... Chung, K. F. (2021). Type 2-low asthma phenotypes by integration of sputum transcriptomics and serum proteomics. Allergy: European Journal of Allergy and Clinical Immunology, 76(1), 380-383. https://doi.org/10.1111/all.14573

@article{402a13ebf10c49a5a974cc865b63abb1,

title = "Type 2-low asthma phenotypes by integration of sputum transcriptomics and serum proteomics",

keywords = "asthma, bioinformatics, endotypes, precision medicine, systems biology",

author = "\{Zounemat Kermani\}, Nazanin and Mansoor Saqi and Paul Agapow and Stelios Pavlidis and Chihhsi Kuo and Tan, \{Kai Sen\} and Sharon Mumby and Kai Sun and Matthew Loza and Frederic Baribaud and Sousa, \{Ana R.\} and John Riley and Wheelock, \{Asa M.\} and Wheelock, \{Craig E.\} and \{de Meulder\}, Bertrand and Jim Schofield and Stephany S{\'a}nchez-Ovando and Simpson, \{Jodie Louise\} and Baines, \{Katherine Joanne\} and Wark, \{Peter A.\} and Charles Auffray and Sven-Erik Dahlen and Sterk, \{Peter J.\} and Ratko Djukanovic and Adcock, \{Ian M.\} and Yi-ke Guo and Chung, \{Kian Fan\}",

note = "Funding Information: U-BIOPRED was supported by an Innovative Medicines Initiative Joint Undertaking (No.115010), resources from the European Union's Seventh Framework Programme (FP7/2007-2013) and EFPIA companies? in-kind contribution (www.imi.europa.eu). Funding Information: U‐BIOPRED was supported by an Innovative Medicines Initiative Joint Undertaking (No.115010), resources from the European Union's Seventh Framework Programme (FP7/2007‐2013) and EFPIA companies{\textquoteright} in‐kind contribution ( www.imi.europa.eu ). Copyright: Copyright 2021 Elsevier B.V., All rights reserved.",

year = "2021",

month = jan,

doi = "10.1111/all.14573",

language = "English",

volume = "76",

pages = "380--383",

journal = "Allergy: European Journal of Allergy and Clinical Immunology",

issn = "0105-4538",

publisher = "Wiley Blackwell",

number = "1",

}

Zounemat Kermani, N, Saqi, M, Agapow, P, Pavlidis, S, Kuo, C, Tan, KS, Mumby, S, Sun, K, Loza, M, Baribaud, F, Sousa, AR, Riley, J, Wheelock, AM, Wheelock, CE, de Meulder, B, Schofield, J, Sánchez-Ovando, S, Simpson, JL, Baines, KJ, Wark, PA, Auffray, C, Dahlen, S-E, Sterk, PJ, Djukanovic, R, Adcock, IM, Guo, Y & Chung, KF 2021, 'Type 2-low asthma phenotypes by integration of sputum transcriptomics and serum proteomics', Allergy: European Journal of Allergy and Clinical Immunology, vol. 76, no. 1, pp. 380-383. https://doi.org/10.1111/all.14573

TY - JOUR

T1 - Type 2-low asthma phenotypes by integration of sputum transcriptomics and serum proteomics

AU - Zounemat Kermani, Nazanin

AU - Saqi, Mansoor

AU - Agapow, Paul

AU - Pavlidis, Stelios

AU - Kuo, Chihhsi

AU - Tan, Kai Sen

AU - Mumby, Sharon

AU - Sun, Kai

AU - Loza, Matthew

AU - Baribaud, Frederic

AU - Sousa, Ana R.

AU - Riley, John

AU - Wheelock, Asa M.

AU - Wheelock, Craig E.

AU - de Meulder, Bertrand

AU - Schofield, Jim

AU - Sánchez-Ovando, Stephany

AU - Simpson, Jodie Louise

AU - Baines, Katherine Joanne

AU - Wark, Peter A.

AU - Auffray, Charles

AU - Dahlen, Sven-Erik

AU - Sterk, Peter J.

AU - Djukanovic, Ratko

AU - Adcock, Ian M.

AU - Guo, Yi-ke

AU - Chung, Kian Fan

N1 - Funding Information: U-BIOPRED was supported by an Innovative Medicines Initiative Joint Undertaking (No.115010), resources from the European Union's Seventh Framework Programme (FP7/2007-2013) and EFPIA companies? in-kind contribution (www.imi.europa.eu). Funding Information: U‐BIOPRED was supported by an Innovative Medicines Initiative Joint Undertaking (No.115010), resources from the European Union's Seventh Framework Programme (FP7/2007‐2013) and EFPIA companies’ in‐kind contribution ( www.imi.europa.eu ). Copyright: Copyright 2021 Elsevier B.V., All rights reserved.

PY - 2021/1

Y1 - 2021/1

KW - asthma

KW - bioinformatics

KW - endotypes

KW - precision medicine

KW - systems biology

UR - https://www.scopus.com/pages/publications/85090946172

U2 - 10.1111/all.14573

DO - 10.1111/all.14573

M3 - Comment/Letter to the editor

C2 - 32865817

SN - 0105-4538

VL - 76

SP - 380

EP - 383

JO - Allergy: European Journal of Allergy and Clinical Immunology

JF - Allergy: European Journal of Allergy and Clinical Immunology

IS - 1

ER -

Type 2-low asthma phenotypes by integration of sputum transcriptomics and serum proteomics

UN SDGs

Keywords

Access to Document

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