Towards optimal care in inflammatory bowel disease: Thiopurines, tofacitinib and impact on working life

S. van Gennep

Towards optimal care in inflammatory bowel disease: Thiopurines, tofacitinib and impact on working life

S. van Gennep

Academic Medical Center/Emma Children’s Hospital
University of Amsterdam
Amsterdam Gastroenterology and Metabolism Research Institute

Research output: PhD Thesis › Phd-Thesis - Research and graduation internal

Abstract

In this thesis, we aimed for further optimization of IBD care by evaluating efficacy and safety of ‘old’ and ‘new’ oral immunomodulators (thiopurines and tofacitinib) and by focusing on the disease impact on working life.
Optimized mercaptopurine treatment based on therapeutic drug monitoring (TDM) is superior to placebo to achieve combined clinical remission and

Original language	English
Qualification	Doctor of Philosophy
Awarding Institution	University of Amsterdam
Supervisors/Advisors	D'Haens, Geert, Supervisor Lowenberg, Mark, Co-supervisor de Boer, K. H. N., Co-supervisor, External person D' Haens, Geert, Supervisor de Boer, Nanne, Co-supervisor
Award date	7 Dec 2023
Print ISBNs	9789493278646
Publication status	Published - 2023

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AB - In this thesis, we aimed for further optimization of IBD care by evaluating efficacy and safety of ‘old’ and ‘new’ oral immunomodulators (thiopurines and tofacitinib) and by focusing on the disease impact on working life. Optimized mercaptopurine treatment based on therapeutic drug monitoring (TDM) is superior to placebo to achieve combined clinical remission and

M3 - Phd-Thesis - Research and graduation internal

SN - 9789493278646

ER -

Towards optimal care in inflammatory bowel disease: Thiopurines, tofacitinib and impact on working life

Abstract

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