TY - JOUR
T1 - Three-dimensional Surface Imaging for Clinical Decision Making in Pectus Excavatum
AU - Daemen, Jean H. T.
AU - Coorens, Nadine A.
AU - Hulsewé, Karel W. E.
AU - Maal, Thomas J. J.
AU - Maessen, Jos G.
AU - Vissers, Yvonne L. J.
AU - de Loos, Erik R.
N1 - Funding Information:
The authors would like to gratefully acknowledge Ernst van Loon and Mirianne Curfs-Theunissen, Medical Photographers (Zuyderland Medical Center, Heerlen, the Netherlands), for acquisition of the 3-dimensional images. Funding: This work was supported by the Zuyderland Research and Innovation Fund of Zuyderland Medical Center (Heerlen, the Netherlands) (2019-005). Conflicts of Interest: None of the authors have any conflicts of interest to declare. In addition, none of the authors have any commercial financial relationships to declare.
Funding Information:
Funding: This work was supported by the Zuyderland Research and Innovation Fund of Zuyderland Medical Center (Heerlen, the Netherlands) (2019-005).
Publisher Copyright:
© 2021 Elsevier Inc.
Copyright:
Copyright 2021 Elsevier B.V., All rights reserved.
PY - 2021
Y1 - 2021
N2 - To evaluate pectus excavatum, 3-dimensional surface imaging is a promising radiation-free alternative to computed tomography and plain radiographs. Given that 3-dimensional images concern the external surface, the conventional Haller index, and correction index are not applicable as these are based on internal diameters. Therefore, external equivalents have been introduced for 3-dimensional images. However, cut-off values to help determine surgical candidacy using external indices are lacking. A prospective cohort study was conducted. Consecutive patients referred for suspected pectus excavatum received a computed tomography (≥18 years) or plain radiographs (<18 years). The external Haller index and external correction index were calculated from additionally acquired 3-dimensional images. Cut-off values for the 3-dimensional image derived indices were obtained by receiver-operating characteristic curve analyses, using a conventional Haller index ≥3.25, and computed tomography derived correction index ≥28.0% as indicative for surgery. Sixty-one and 63 patients were included in the computed tomography and radiograph group, respectively. To determine potential surgical candidacy, receiver-operating characteristic analyses found an optimum cut-off of ≥1.83 for the external Haller index in both the computed tomography and radiograph group with a positive predictive value between 0.90 and 0.97 and a negative predictive value between 0.72 and 0.81. The optimal cut-off for the external correction index was ≥15.2% with a positive predictive value of 0.86 and negative predictive value of 0.93. The 3-dimensional image derived external Haller index and external correction index are accurate radiation-free alternatives to facilitate surgical decision-making among patients suspected of pectus excavatum with values of ≥1.83 and ≥15.2% indicative for surgery.
AB - To evaluate pectus excavatum, 3-dimensional surface imaging is a promising radiation-free alternative to computed tomography and plain radiographs. Given that 3-dimensional images concern the external surface, the conventional Haller index, and correction index are not applicable as these are based on internal diameters. Therefore, external equivalents have been introduced for 3-dimensional images. However, cut-off values to help determine surgical candidacy using external indices are lacking. A prospective cohort study was conducted. Consecutive patients referred for suspected pectus excavatum received a computed tomography (≥18 years) or plain radiographs (<18 years). The external Haller index and external correction index were calculated from additionally acquired 3-dimensional images. Cut-off values for the 3-dimensional image derived indices were obtained by receiver-operating characteristic curve analyses, using a conventional Haller index ≥3.25, and computed tomography derived correction index ≥28.0% as indicative for surgery. Sixty-one and 63 patients were included in the computed tomography and radiograph group, respectively. To determine potential surgical candidacy, receiver-operating characteristic analyses found an optimum cut-off of ≥1.83 for the external Haller index in both the computed tomography and radiograph group with a positive predictive value between 0.90 and 0.97 and a negative predictive value between 0.72 and 0.81. The optimal cut-off for the external correction index was ≥15.2% with a positive predictive value of 0.86 and negative predictive value of 0.93. The 3-dimensional image derived external Haller index and external correction index are accurate radiation-free alternatives to facilitate surgical decision-making among patients suspected of pectus excavatum with values of ≥1.83 and ≥15.2% indicative for surgery.
KW - Computed tomography
KW - External Haller index
KW - Haller index
KW - Pectus excavatum
KW - Three-dimensional surface imaging
UR - https://www.scopus.com/pages/publications/85113822246
U2 - 10.1053/j.semtcvs.2021.08.002
DO - 10.1053/j.semtcvs.2021.08.002
M3 - Article
C2 - 34380079
SN - 1043-0679
JO - Seminars in thoracic and cardiovascular surgery
JF - Seminars in thoracic and cardiovascular surgery
ER -