The Role of Adiposity in Cardiometabolic Traits: A Mendelian Randomization Analysis

T. Fall; S. Hägg; R. Mägi; A. Ploner; K. Fischer; M. Horikoshi; A.P. Sarin; G. Thorleifsson; C. Ladenvall; M. Kals; M. Kuningas; H.H.M. Draisma; J.S. Ried; N.R. van Zuydam; V. Huikari; M. Mangino; E. Sonestedt; B. Benyamin; C.P. Nelson; N.V. Rivera; K. Kristiansson; H.Y. Shen; A.S. Havulinna; A. Dehghan; L.A. Donnelly; M. Kaakinen; M.L. Nuotio; N. Robertson; R.F. de Bruijn; M.A. Ikram; N. Amin; A.J. Balmforth; P.S. Braund; A.S.F. Doney; A. Döring; P. Elliott; T. Esko; O.H. Franco; S. Gretarsdottir; A.L. Hartikainen; K. Heikkilä; K.H. Herzig; H. Holm; J.J. Hottenga; E. Hyppönen; T. Illig; A. Isaacs; B. Isomaa; L.C. Karssen; J. Kettunen; W. Koenig; K. Kuulasmaa; T. Laatikainen; J. Laitinen; C.M. Lindgren; V. Lyssenko; E. Läärä; N.W. Rayner; S. Männistö; A. Pouta; W. Rathmann; F. Rivadeneira; A. Ruokonen; M.J. Savolainen; E.J. Sijbrands; K.S. Small; J.H. Smit; V. Steinthorsdottir; A.C. Syvänen; A. Taanila; M.D. Tobin; A.G. Uitterlinden; S.M. Willems; G. Willemsen; J. Witteman; M. Perola; A. Evans; J. Ferrières; J. Virtamo; F Kee; D.A. Tregouet; D. Arveiler; P. Amouyel; M.M. Ferrario; P. Brambilla; A.S. Hall; A.C. Heath; P.A.F. Madden; N.G. Martin; G.W. Montgomery; J.B. Whitfield; A. Jula; P. Knekt; B.A. Oostra; C.M. van Duijn; B.W.J.H. Penninx; G. Davey Smith; J. Kaprio; N.J. Samani; C. Gieger; A. Peters; H.E. Wichmann; D.I. Boomsma; E.J.C. de Geus; T. Tuomi; C. Power; C.J. Hammond; T.D. Spector; L. Lind; M. Orho-Melander; C.N.A. Palmer; A.D. Morris; L. Groop; M.R. Järvelin; V. Salomaa; E. Vartiainen; A. Hofman; S. Ripatti; A. Metspalu; U. Thorsteinsdottir; K. Stefansson; N.L. Pedersen; M.I. McCarthy; E. Ingelsson; I. Prokopenko

doi:10.1371/journal.pmed.1001474

The Role of Adiposity in Cardiometabolic Traits: A Mendelian Randomization Analysis

T. Fall
, S. Hägg
, R. Mägi
, A. Ploner
, K. Fischer
, M. Horikoshi
, A.P. Sarin
, G. Thorleifsson
, C. Ladenvall
, M. Kals
, M. Kuningas
, H.H.M. Draisma
, J.S. Ried
, N.R. van Zuydam
, V. Huikari
, M. Mangino
, E. Sonestedt
, B. Benyamin
, C.P. Nelson
, N.V. Rivera

K. Kristiansson, H.Y. Shen, A.S. Havulinna, A. Dehghan, L.A. Donnelly, M. Kaakinen, M.L. Nuotio, N. Robertson, R.F. de Bruijn, M.A. Ikram, N. Amin, A.J. Balmforth, P.S. Braund, A.S.F. Doney, A. Döring, P. Elliott, T. Esko, O.H. Franco, S. Gretarsdottir, A.L. Hartikainen, K. Heikkilä, K.H. Herzig, H. Holm, J.J. Hottenga, E. Hyppönen, T. Illig, A. Isaacs, B. Isomaa, L.C. Karssen, J. Kettunen, W. Koenig, K. Kuulasmaa, T. Laatikainen, J. Laitinen, C.M. Lindgren, V. Lyssenko, E. Läärä, N.W. Rayner, S. Männistö, A. Pouta, W. Rathmann, F. Rivadeneira, A. Ruokonen, M.J. Savolainen, E.J. Sijbrands, K.S. Small, J.H. Smit, V. Steinthorsdottir, A.C. Syvänen, A. Taanila, M.D. Tobin, A.G. Uitterlinden, S.M. Willems, G. Willemsen, J. Witteman, M. Perola, A. Evans, J. Ferrières, J. Virtamo, F Kee, D.A. Tregouet, D. Arveiler, P. Amouyel, M.M. Ferrario, P. Brambilla, A.S. Hall, A.C. Heath, P.A.F. Madden, N.G. Martin, G.W. Montgomery, J.B. Whitfield, A. Jula, P. Knekt, B.A. Oostra, C.M. van Duijn, B.W.J.H. Penninx, G. Davey Smith, J. Kaprio, N.J. Samani, C. Gieger, A. Peters, H.E. Wichmann, D.I. Boomsma, E.J.C. de Geus, T. Tuomi, C. Power, C.J. Hammond, T.D. Spector, L. Lind, M. Orho-Melander, C.N.A. Palmer, A.D. Morris, L. Groop, M.R. Järvelin, V. Salomaa, E. Vartiainen, A. Hofman, S. Ripatti, A. Metspalu, U. Thorsteinsdottir, K. Stefansson, N.L. Pedersen, M.I. McCarthy, E. Ingelsson, I. Prokopenko

Research output: Contribution to journal › Article › Academic › peer-review

Original language	English
Article number	e1001474
Pages (from-to)	e1001474
Journal	PLoS medicine
Volume	10
Issue number	6
DOIs	https://doi.org/10.1371/journal.pmed.1001474
Publication status	Published - 2013

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Access to Document

10.1371/journal.pmed.1001474

Netherlands Study of Depression and Anxiety (NESDA)
Penninx, B. (PI), Riemsma, S. (Data Manager), Viegas Calçada, D. (Data Manager), Zandbelt, T. (Data Manager), Eikelenboom, M. (Coordinator), Horsfall, M. (Coordinator), Lamers, F. (Researcher), Han, L. (Researcher), Milaneschi, Y. (Researcher), Braak, S. (Researcher) & Jansen, R. (Researcher)
Psychiatry
Facility/equipment: Facility

Cite this

Fall, T., Hägg, S., Mägi, R., Ploner, A., Fischer, K., Horikoshi, M., Sarin, A. P., Thorleifsson, G., Ladenvall, C., Kals, M., Kuningas, M., Draisma, H. H. M., Ried, J. S., van Zuydam, N. R., Huikari, V., Mangino, M., Sonestedt, E., Benyamin, B., Nelson, C. P., ... Prokopenko, I. (2013). The Role of Adiposity in Cardiometabolic Traits: A Mendelian Randomization Analysis. PLoS medicine, 10(6), e1001474. Article e1001474. https://doi.org/10.1371/journal.pmed.1001474

@article{b431fe4efc8b49b889f9343e8fe5337d,

title = "The Role of Adiposity in Cardiometabolic Traits: A Mendelian Randomization Analysis",

author = "T. Fall and S. H{\"a}gg and R. M{\"a}gi and A. Ploner and K. Fischer and M. Horikoshi and A.P. Sarin and G. Thorleifsson and C. Ladenvall and M. Kals and M. Kuningas and H.H.M. Draisma and J.S. Ried and \{van Zuydam\}, N.R. and V. Huikari and M. Mangino and E. Sonestedt and B. Benyamin and C.P. Nelson and N.V. Rivera and K. Kristiansson and H.Y. Shen and A.S. Havulinna and A. Dehghan and L.A. Donnelly and M. Kaakinen and M.L. Nuotio and N. Robertson and \{de Bruijn\}, R.F. and M.A. Ikram and N. Amin and A.J. Balmforth and P.S. Braund and A.S.F. Doney and A. D{\"o}ring and P. Elliott and T. Esko and O.H. Franco and S. Gretarsdottir and A.L. Hartikainen and K. Heikkil{\"a} and K.H. Herzig and H. Holm and J.J. Hottenga and E. Hypp{\"o}nen and T. Illig and A. Isaacs and B. Isomaa and L.C. Karssen and J. Kettunen and W. Koenig and K. Kuulasmaa and T. Laatikainen and J. Laitinen and C.M. Lindgren and V. Lyssenko and E. L{\"a}{\"a}r{\"a} and N.W. Rayner and S. M{\"a}nnist{\"o} and A. Pouta and W. Rathmann and F. Rivadeneira and A. Ruokonen and M.J. Savolainen and E.J. Sijbrands and K.S. Small and J.H. Smit and V. Steinthorsdottir and A.C. Syv{\"a}nen and A. Taanila and M.D. Tobin and A.G. Uitterlinden and S.M. Willems and G. Willemsen and J. Witteman and M. Perola and A. Evans and J. Ferri{\`e}res and J. Virtamo and F Kee and D.A. Tregouet and D. Arveiler and P. Amouyel and M.M. Ferrario and P. Brambilla and A.S. Hall and A.C. Heath and P.A.F. Madden and N.G. Martin and G.W. Montgomery and J.B. Whitfield and A. Jula and P. Knekt and B.A. Oostra and \{van Duijn\}, C.M. and B.W.J.H. Penninx and \{Davey Smith\}, G. and J. Kaprio and N.J. Samani and C. Gieger and A. Peters and H.E. Wichmann and D.I. Boomsma and \{de Geus\}, E.J.C. and T. Tuomi and C. Power and C.J. Hammond and T.D. Spector and L. Lind and M. Orho-Melander and C.N.A. Palmer and A.D. Morris and L. Groop and M.R. J{\"a}rvelin and V. Salomaa and E. Vartiainen and A. Hofman and S. Ripatti and A. Metspalu and U. Thorsteinsdottir and K. Stefansson and N.L. Pedersen and M.I. McCarthy and E. Ingelsson and I. Prokopenko",

year = "2013",

doi = "10.1371/journal.pmed.1001474",

language = "English",

volume = "10",

pages = "e1001474",

journal = "PLoS medicine",

issn = "1549-1277",

publisher = "Public Library of Science",

number = "6",

}

Fall, T, Hägg, S, Mägi, R, Ploner, A, Fischer, K, Horikoshi, M, Sarin, AP, Thorleifsson, G, Ladenvall, C, Kals, M, Kuningas, M, Draisma, HHM, Ried, JS, van Zuydam, NR, Huikari, V, Mangino, M, Sonestedt, E, Benyamin, B, Nelson, CP, Rivera, NV, Kristiansson, K, Shen, HY, Havulinna, AS, Dehghan, A, Donnelly, LA, Kaakinen, M, Nuotio, ML, Robertson, N, de Bruijn, RF, Ikram, MA, Amin, N, Balmforth, AJ, Braund, PS, Doney, ASF, Döring, A, Elliott, P, Esko, T, Franco, OH, Gretarsdottir, S, Hartikainen, AL, Heikkilä, K, Herzig, KH, Holm, H, Hottenga, JJ, Hyppönen, E, Illig, T, Isaacs, A, Isomaa, B, Karssen, LC, Kettunen, J, Koenig, W, Kuulasmaa, K, Laatikainen, T, Laitinen, J, Lindgren, CM, Lyssenko, V, Läärä, E, Rayner, NW, Männistö, S, Pouta, A, Rathmann, W, Rivadeneira, F, Ruokonen, A, Savolainen, MJ, Sijbrands, EJ, Small, KS, Smit, JH, Steinthorsdottir, V, Syvänen, AC, Taanila, A, Tobin, MD, Uitterlinden, AG, Willems, SM, Willemsen, G, Witteman, J, Perola, M, Evans, A, Ferrières, J, Virtamo, J, Kee, F, Tregouet, DA, Arveiler, D, Amouyel, P, Ferrario, MM, Brambilla, P, Hall, AS, Heath, AC, Madden, PAF, Martin, NG, Montgomery, GW, Whitfield, JB, Jula, A, Knekt, P, Oostra, BA, van Duijn, CM, Penninx, BWJH, Davey Smith, G, Kaprio, J, Samani, NJ, Gieger, C, Peters, A, Wichmann, HE, Boomsma, DI, de Geus, EJC, Tuomi, T, Power, C, Hammond, CJ, Spector, TD, Lind, L, Orho-Melander, M, Palmer, CNA, Morris, AD, Groop, L, Järvelin, MR, Salomaa, V, Vartiainen, E, Hofman, A, Ripatti, S, Metspalu, A, Thorsteinsdottir, U, Stefansson, K, Pedersen, NL, McCarthy, MI, Ingelsson, E & Prokopenko, I 2013, 'The Role of Adiposity in Cardiometabolic Traits: A Mendelian Randomization Analysis', PLoS medicine, vol. 10, no. 6, e1001474, pp. e1001474. https://doi.org/10.1371/journal.pmed.1001474

TY - JOUR

T1 - The Role of Adiposity in Cardiometabolic Traits: A Mendelian Randomization Analysis

AU - Fall, T.

AU - Hägg, S.

AU - Mägi, R.

AU - Ploner, A.

AU - Fischer, K.

AU - Horikoshi, M.

AU - Sarin, A.P.

AU - Thorleifsson, G.

AU - Ladenvall, C.

AU - Kals, M.

AU - Kuningas, M.

AU - Draisma, H.H.M.

AU - Ried, J.S.

AU - van Zuydam, N.R.

AU - Huikari, V.

AU - Mangino, M.

AU - Sonestedt, E.

AU - Benyamin, B.

AU - Nelson, C.P.

AU - Rivera, N.V.

AU - Kristiansson, K.

AU - Shen, H.Y.

AU - Havulinna, A.S.

AU - Dehghan, A.

AU - Donnelly, L.A.

AU - Kaakinen, M.

AU - Nuotio, M.L.

AU - Robertson, N.

AU - de Bruijn, R.F.

AU - Ikram, M.A.

AU - Amin, N.

AU - Balmforth, A.J.

AU - Braund, P.S.

AU - Doney, A.S.F.

AU - Döring, A.

AU - Elliott, P.

AU - Esko, T.

AU - Franco, O.H.

AU - Gretarsdottir, S.

AU - Hartikainen, A.L.

AU - Heikkilä, K.

AU - Herzig, K.H.

AU - Holm, H.

AU - Hottenga, J.J.

AU - Hyppönen, E.

AU - Illig, T.

AU - Isaacs, A.

AU - Isomaa, B.

AU - Karssen, L.C.

AU - Kettunen, J.

AU - Koenig, W.

AU - Kuulasmaa, K.

AU - Laatikainen, T.

AU - Laitinen, J.

AU - Lindgren, C.M.

AU - Lyssenko, V.

AU - Läärä, E.

AU - Rayner, N.W.

AU - Männistö, S.

AU - Pouta, A.

AU - Rathmann, W.

AU - Rivadeneira, F.

AU - Ruokonen, A.

AU - Savolainen, M.J.

AU - Sijbrands, E.J.

AU - Small, K.S.

AU - Smit, J.H.

AU - Steinthorsdottir, V.

AU - Syvänen, A.C.

AU - Taanila, A.

AU - Tobin, M.D.

AU - Uitterlinden, A.G.

AU - Willems, S.M.

AU - Willemsen, G.

AU - Witteman, J.

AU - Perola, M.

AU - Evans, A.

AU - Ferrières, J.

AU - Virtamo, J.

AU - Kee, F

AU - Tregouet, D.A.

AU - Arveiler, D.

AU - Amouyel, P.

AU - Ferrario, M.M.

AU - Brambilla, P.

AU - Hall, A.S.

AU - Heath, A.C.

AU - Madden, P.A.F.

AU - Martin, N.G.

AU - Montgomery, G.W.

AU - Whitfield, J.B.

AU - Jula, A.

AU - Knekt, P.

AU - Oostra, B.A.

AU - van Duijn, C.M.

AU - Penninx, B.W.J.H.

AU - Davey Smith, G.

AU - Kaprio, J.

AU - Samani, N.J.

AU - Gieger, C.

AU - Peters, A.

AU - Wichmann, H.E.

AU - Boomsma, D.I.

AU - de Geus, E.J.C.

AU - Tuomi, T.

AU - Power, C.

AU - Hammond, C.J.

AU - Spector, T.D.

AU - Lind, L.

AU - Orho-Melander, M.

AU - Palmer, C.N.A.

AU - Morris, A.D.

AU - Groop, L.

AU - Järvelin, M.R.

AU - Salomaa, V.

AU - Vartiainen, E.

AU - Hofman, A.

AU - Ripatti, S.

AU - Metspalu, A.

AU - Thorsteinsdottir, U.

AU - Stefansson, K.

AU - Pedersen, N.L.

AU - McCarthy, M.I.

AU - Ingelsson, E.

AU - Prokopenko, I.

PY - 2013

Y1 - 2013

U2 - 10.1371/journal.pmed.1001474

DO - 10.1371/journal.pmed.1001474

M3 - Article

C2 - 23824655

SN - 1549-1277

VL - 10

SP - e1001474

JO - PLoS medicine

JF - PLoS medicine

IS - 6

M1 - e1001474

ER -

The Role of Adiposity in Cardiometabolic Traits: A Mendelian Randomization Analysis

UN SDGs

Access to Document

Cohorts

Netherlands Study of Depression and Anxiety (NESDA)

Cite this