The interaction between anticoagulant protein S and complement regulatory C4b-binding protein (C4BP)

R. H. van de Poel; J. C. Meijers; B. N. Bouma

doi:10.1016/S1050-1738(00)00051-7

The interaction between anticoagulant protein S and complement regulatory C4b-binding protein (C4BP)

R. H. van de Poel
, J. C. Meijers
, B. N. Bouma

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

An important mechanism of regulation of blood coagulation is the anticoagulant protein C pathway. In this pathway, the anticoagulant activity of activated protein C is increased by its cofactor protein S. The cofactor activity of protein S can be regulated by binding to complement regulatory C4b-binding protein (C4BP). The sites of interaction of protein S and C4BP are discussed

Original language	English
Pages (from-to)	71-76
Journal	Trends in cardiovascular medicine
Volume	10
Issue number	2
DOIs	https://doi.org/10.1016/S1050-1738(00)00051-7
Publication status	Published - 2000

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title = "The interaction between anticoagulant protein S and complement regulatory C4b-binding protein (C4BP)",

abstract = "An important mechanism of regulation of blood coagulation is the anticoagulant protein C pathway. In this pathway, the anticoagulant activity of activated protein C is increased by its cofactor protein S. The cofactor activity of protein S can be regulated by binding to complement regulatory C4b-binding protein (C4BP). The sites of interaction of protein S and C4BP are discussed",

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AU - Bouma, B. N.

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AB - An important mechanism of regulation of blood coagulation is the anticoagulant protein C pathway. In this pathway, the anticoagulant activity of activated protein C is increased by its cofactor protein S. The cofactor activity of protein S can be regulated by binding to complement regulatory C4b-binding protein (C4BP). The sites of interaction of protein S and C4BP are discussed

U2 - 10.1016/S1050-1738(00)00051-7

DO - 10.1016/S1050-1738(00)00051-7

M3 - Article

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SP - 71

EP - 76

JO - Trends in cardiovascular medicine

JF - Trends in cardiovascular medicine

IS - 2

ER -

The interaction between anticoagulant protein S and complement regulatory C4b-binding protein (C4BP)

Abstract

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