The impact of low-frequency and rare variants on lipid levels

I. Surakka; M. Horikoshi; R. Magi; A. Sarin; A. Mahajan; V. Lagou; L. Marullo; T. Ferreira; B. Miraglio; S. Timonen; J. Kettunen; M. Pirinen; J. Karjalainen; G. Thorleifsson; S. Hagg; J.J. Hottenga; A. Isaacs; C. Ladenvall; M. Beekman; T. Esko; J.S. Ried; C.P. Nelson; C. Willenborg; S. Gustafsson; H. Westra; M. Blades; A.J.M. Craen; E.J.C. de Geus; J. Deelen; H. Grallert; A. Hamsten; A.S. Havulinna; C. Hengstenberg; J.J. Houwing-Duistermaat; E. Hypponen; L.C. Karssen; T. Lehtimaki; V. Lyssenko; P.K.E. Magnusson; E. Mihailov; M. Muller-Nurasyid; J. Mpindi; N.L. Pedersen; B.W.J.H. Penninx; M. Perola; T.H. Pers; A. Peters; J. Rung; J.H. Smit; V. Steinthorsdottir; M.D. Tobin; N. Tsernikova; E.M. van Leeuwen; J.S. Viikari; S.M. Willems; G. Willemsen; H. Schunkert; J. Erdmann; N.J. Samani; J. Kaprio; L. Lind; C. Gieger; A. Metspalu; P.E. Slagboom; L. Groop; C.M. van Duijn; J.G. Eriksson; A. Jula; V. Salomaa; D.I. Boomsma; C. Power; O.T. Raitakari; E. Ingelsson; M. Jarvelin; U. Thorsteinsdottir; L. Franke; E. Ikonen; O. Kallioniemi; V. Pietiainen; C.M. Lindgren; K. Stefansson; A. Palotie; M.I. McCarthy; A.P. Morris; I. Prokopenko; S. Ripatti

doi:10.1038/ng.3300

The impact of low-frequency and rare variants on lipid levels

I. Surakka
, M. Horikoshi
, R. Magi
, A. Sarin
, A. Mahajan
, V. Lagou
, L. Marullo
, T. Ferreira
, B. Miraglio
, S. Timonen
, J. Kettunen
, M. Pirinen
, J. Karjalainen
, G. Thorleifsson
, S. Hagg
, J.J. Hottenga
, A. Isaacs
, C. Ladenvall
, M. Beekman
, T. Esko

J.S. Ried, C.P. Nelson, C. Willenborg, S. Gustafsson, H. Westra, M. Blades, A.J.M. Craen, E.J.C. de Geus, J. Deelen, H. Grallert, A. Hamsten, A.S. Havulinna, C. Hengstenberg, J.J. Houwing-Duistermaat, E. Hypponen, L.C. Karssen, T. Lehtimaki, V. Lyssenko, P.K.E. Magnusson, E. Mihailov, M. Muller-Nurasyid, J. Mpindi, N.L. Pedersen, B.W.J.H. Penninx, M. Perola, T.H. Pers, A. Peters, J. Rung, J.H. Smit, V. Steinthorsdottir, M.D. Tobin, N. Tsernikova, E.M. van Leeuwen, J.S. Viikari, S.M. Willems, G. Willemsen, H. Schunkert, J. Erdmann, N.J. Samani, J. Kaprio, L. Lind, C. Gieger, A. Metspalu, P.E. Slagboom, L. Groop, C.M. van Duijn, J.G. Eriksson, A. Jula, V. Salomaa, D.I. Boomsma, C. Power, O.T. Raitakari, E. Ingelsson, M. Jarvelin, U. Thorsteinsdottir, L. Franke, E. Ikonen, O. Kallioniemi, V. Pietiainen, C.M. Lindgren, K. Stefansson, A. Palotie, M.I. McCarthy, A.P. Morris, I. Prokopenko, S. Ripatti

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Original language	Undefined/Unknown
Pages (from-to)	589-597
Journal	Nature genetics
Volume	47
Issue number	6
DOIs	https://doi.org/10.1038/ng.3300
Publication status	Published - 2015

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10.1038/ng.3300

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Netherlands Study of Depression and Anxiety (NESDA)
Penninx, B. (PI), Riemsma, S. (Data Manager), Viegas Calçada, D. (Data Manager), Zandbelt, T. (Data Manager), Eikelenboom, M. (Coordinator), Horsfall, M. (Coordinator), Lamers, F. (Researcher), Han, L. (Researcher), Milaneschi, Y. (Researcher), Braak, S. (Researcher) & Jansen, R. (Researcher)
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Surakka, I., Horikoshi, M., Magi, R., Sarin, A., Mahajan, A., Lagou, V., Marullo, L., Ferreira, T., Miraglio, B., Timonen, S., Kettunen, J., Pirinen, M., Karjalainen, J., Thorleifsson, G., Hagg, S., Hottenga, J. J., Isaacs, A., Ladenvall, C., Beekman, M., ... Ripatti, S. (2015). The impact of low-frequency and rare variants on lipid levels. Nature genetics, 47(6), 589-597. https://doi.org/10.1038/ng.3300

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author = "I. Surakka and M. Horikoshi and R. Magi and A. Sarin and A. Mahajan and V. Lagou and L. Marullo and T. Ferreira and B. Miraglio and S. Timonen and J. Kettunen and M. Pirinen and J. Karjalainen and G. Thorleifsson and S. Hagg and J.J. Hottenga and A. Isaacs and C. Ladenvall and M. Beekman and T. Esko and J.S. Ried and C.P. Nelson and C. Willenborg and S. Gustafsson and H. Westra and M. Blades and A.J.M. Craen and \{de Geus\}, E.J.C. and J. Deelen and H. Grallert and A. Hamsten and A.S. Havulinna and C. Hengstenberg and J.J. Houwing-Duistermaat and E. Hypponen and L.C. Karssen and T. Lehtimaki and V. Lyssenko and P.K.E. Magnusson and E. Mihailov and M. Muller-Nurasyid and J. Mpindi and N.L. Pedersen and B.W.J.H. Penninx and M. Perola and T.H. Pers and A. Peters and J. Rung and J.H. Smit and V. Steinthorsdottir and M.D. Tobin and N. Tsernikova and \{van Leeuwen\}, E.M. and J.S. Viikari and S.M. Willems and G. Willemsen and H. Schunkert and J. Erdmann and N.J. Samani and J. Kaprio and L. Lind and C. Gieger and A. Metspalu and P.E. Slagboom and L. Groop and \{van Duijn\}, C.M. and J.G. Eriksson and A. Jula and V. Salomaa and D.I. Boomsma and C. Power and O.T. Raitakari and E. Ingelsson and M. Jarvelin and U. Thorsteinsdottir and L. Franke and E. Ikonen and O. Kallioniemi and V. Pietiainen and C.M. Lindgren and K. Stefansson and A. Palotie and M.I. McCarthy and A.P. Morris and I. Prokopenko and S. Ripatti",

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doi = "10.1038/ng.3300",

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volume = "47",

pages = "589--597",

journal = "Nature genetics",

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Surakka, I, Horikoshi, M, Magi, R, Sarin, A, Mahajan, A, Lagou, V, Marullo, L, Ferreira, T, Miraglio, B, Timonen, S, Kettunen, J, Pirinen, M, Karjalainen, J, Thorleifsson, G, Hagg, S, Hottenga, JJ, Isaacs, A, Ladenvall, C, Beekman, M, Esko, T, Ried, JS, Nelson, CP, Willenborg, C, Gustafsson, S, Westra, H, Blades, M, Craen, AJM, de Geus, EJC, Deelen, J, Grallert, H, Hamsten, A, Havulinna, AS, Hengstenberg, C, Houwing-Duistermaat, JJ, Hypponen, E, Karssen, LC, Lehtimaki, T, Lyssenko, V, Magnusson, PKE, Mihailov, E, Muller-Nurasyid, M, Mpindi, J, Pedersen, NL, Penninx, BWJH, Perola, M, Pers, TH, Peters, A, Rung, J, Smit, JH, Steinthorsdottir, V, Tobin, MD, Tsernikova, N, van Leeuwen, EM, Viikari, JS, Willems, SM, Willemsen, G, Schunkert, H, Erdmann, J, Samani, NJ, Kaprio, J, Lind, L, Gieger, C, Metspalu, A, Slagboom, PE, Groop, L, van Duijn, CM, Eriksson, JG, Jula, A, Salomaa, V, Boomsma, DI, Power, C, Raitakari, OT, Ingelsson, E, Jarvelin, M, Thorsteinsdottir, U, Franke, L, Ikonen, E, Kallioniemi, O, Pietiainen, V, Lindgren, CM, Stefansson, K, Palotie, A, McCarthy, MI, Morris, AP, Prokopenko, I & Ripatti, S 2015, 'The impact of low-frequency and rare variants on lipid levels', Nature genetics, vol. 47, no. 6, pp. 589-597. https://doi.org/10.1038/ng.3300

TY - JOUR

T1 - The impact of low-frequency and rare variants on lipid levels

AU - Surakka, I.

AU - Horikoshi, M.

AU - Magi, R.

AU - Sarin, A.

AU - Mahajan, A.

AU - Lagou, V.

AU - Marullo, L.

AU - Ferreira, T.

AU - Miraglio, B.

AU - Timonen, S.

AU - Kettunen, J.

AU - Pirinen, M.

AU - Karjalainen, J.

AU - Thorleifsson, G.

AU - Hagg, S.

AU - Hottenga, J.J.

AU - Isaacs, A.

AU - Ladenvall, C.

AU - Beekman, M.

AU - Esko, T.

AU - Ried, J.S.

AU - Nelson, C.P.

AU - Willenborg, C.

AU - Gustafsson, S.

AU - Westra, H.

AU - Blades, M.

AU - Craen, A.J.M.

AU - de Geus, E.J.C.

AU - Deelen, J.

AU - Grallert, H.

AU - Hamsten, A.

AU - Havulinna, A.S.

AU - Hengstenberg, C.

AU - Houwing-Duistermaat, J.J.

AU - Hypponen, E.

AU - Karssen, L.C.

AU - Lehtimaki, T.

AU - Lyssenko, V.

AU - Magnusson, P.K.E.

AU - Mihailov, E.

AU - Muller-Nurasyid, M.

AU - Mpindi, J.

AU - Pedersen, N.L.

AU - Penninx, B.W.J.H.

AU - Perola, M.

AU - Pers, T.H.

AU - Peters, A.

AU - Rung, J.

AU - Smit, J.H.

AU - Steinthorsdottir, V.

AU - Tobin, M.D.

AU - Tsernikova, N.

AU - van Leeuwen, E.M.

AU - Viikari, J.S.

AU - Willems, S.M.

AU - Willemsen, G.

AU - Schunkert, H.

AU - Erdmann, J.

AU - Samani, N.J.

AU - Kaprio, J.

AU - Lind, L.

AU - Gieger, C.

AU - Metspalu, A.

AU - Slagboom, P.E.

AU - Groop, L.

AU - van Duijn, C.M.

AU - Eriksson, J.G.

AU - Jula, A.

AU - Salomaa, V.

AU - Boomsma, D.I.

AU - Power, C.

AU - Raitakari, O.T.

AU - Ingelsson, E.

AU - Jarvelin, M.

AU - Thorsteinsdottir, U.

AU - Franke, L.

AU - Ikonen, E.

AU - Kallioniemi, O.

AU - Pietiainen, V.

AU - Lindgren, C.M.

AU - Stefansson, K.

AU - Palotie, A.

AU - McCarthy, M.I.

AU - Morris, A.P.

AU - Prokopenko, I.

AU - Ripatti, S.

PY - 2015

Y1 - 2015

U2 - 10.1038/ng.3300

DO - 10.1038/ng.3300

M3 - Article

C2 - 25961943

SN - 1061-4036

VL - 47

SP - 589

EP - 597

JO - Nature genetics

JF - Nature genetics

IS - 6

ER -

The impact of low-frequency and rare variants on lipid levels

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