The healing of biologic and synthetic bone implants - An Experimental Study

A. D. Verburg; P. J. Klopper; A. van den Hooff; R. K. Marti; P. E. Ochsner

doi:10.1007/BF00451510

The healing of biologic and synthetic bone implants - An Experimental Study

A. D. Verburg^*
, P. J. Klopper
, A. van den Hooff
, R. K. Marti
, P. E. Ochsner

^*Corresponding author for this work

Ziekenhuis Sittard
Amsterdam UMC - University of Amsterdam

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

The aim of the present study was to investigate the osteogenic properties of different types of cancellous bone grafts inserted in large osseous defects in dogs and to compare these with those of sintered hydroxyapatite implants. Fresh cancellous autografts were rapidly revascularized and invariably induced a complete healing of the defect. Frozen and fresh cancellous allografts were largely resorbed, the latter evoking a strong antigenic response in two of the five cases. Sintered hydroxyapatite granules were largely encapsulated in fibrous tissue, neither stimulating nor inhibiting osseous ingrowth. Degradation of the hydroxyapatite implant was not observed. © 1988 Springer-Verlag.

Original language	English
Pages (from-to)	293-300
Journal	Archives of orthopaedic and trauma surgery
Volume	107
Issue number	5
DOIs	https://doi.org/10.1007/BF00451510
Publication status	Published - Aug 1988
Externally published	Yes

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title = "The healing of biologic and synthetic bone implants - An Experimental Study",

abstract = "The aim of the present study was to investigate the osteogenic properties of different types of cancellous bone grafts inserted in large osseous defects in dogs and to compare these with those of sintered hydroxyapatite implants. Fresh cancellous autografts were rapidly revascularized and invariably induced a complete healing of the defect. Frozen and fresh cancellous allografts were largely resorbed, the latter evoking a strong antigenic response in two of the five cases. Sintered hydroxyapatite granules were largely encapsulated in fibrous tissue, neither stimulating nor inhibiting osseous ingrowth. Degradation of the hydroxyapatite implant was not observed. {\textcopyright} 1988 Springer-Verlag.",

author = "Verburg, \{A. D.\} and Klopper, \{P. J.\} and \{van den Hooff\}, A. and Marti, \{R. K.\} and Ochsner, \{P. E.\}",

year = "1988",

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AU - Verburg, A. D.

AU - Klopper, P. J.

AU - van den Hooff, A.

AU - Marti, R. K.

AU - Ochsner, P. E.

PY - 1988/8

Y1 - 1988/8

N2 - The aim of the present study was to investigate the osteogenic properties of different types of cancellous bone grafts inserted in large osseous defects in dogs and to compare these with those of sintered hydroxyapatite implants. Fresh cancellous autografts were rapidly revascularized and invariably induced a complete healing of the defect. Frozen and fresh cancellous allografts were largely resorbed, the latter evoking a strong antigenic response in two of the five cases. Sintered hydroxyapatite granules were largely encapsulated in fibrous tissue, neither stimulating nor inhibiting osseous ingrowth. Degradation of the hydroxyapatite implant was not observed. © 1988 Springer-Verlag.

AB - The aim of the present study was to investigate the osteogenic properties of different types of cancellous bone grafts inserted in large osseous defects in dogs and to compare these with those of sintered hydroxyapatite implants. Fresh cancellous autografts were rapidly revascularized and invariably induced a complete healing of the defect. Frozen and fresh cancellous allografts were largely resorbed, the latter evoking a strong antigenic response in two of the five cases. Sintered hydroxyapatite granules were largely encapsulated in fibrous tissue, neither stimulating nor inhibiting osseous ingrowth. Degradation of the hydroxyapatite implant was not observed. © 1988 Springer-Verlag.

UR - https://www.scopus.com/pages/publications/0023693689

UR - https://www.ncbi.nlm.nih.gov/pubmed/3052361

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DO - 10.1007/BF00451510

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SN - 0936-8051

VL - 107

SP - 293

EP - 300

JO - Archives of orthopaedic and trauma surgery

JF - Archives of orthopaedic and trauma surgery

IS - 5

ER -

The healing of biologic and synthetic bone implants - An Experimental Study

Abstract

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