T-cell and antibody responses in immunocompromised patients with hematologic malignancies indicate strong potential of SARS-CoV-2 mRNA vaccines

Cilia R. Pothast; Quincy Hofsink; Sabine Haggenburg; Romy C. Dijkland; Marian van de Meent; Kayleigh van Dijk; Michel S. Bhoekhan; Nienke J. E. Haverkate; Johan van Meerloo; J. H. Frederik Falkenburg; Ruben A. L. de Groen; Annoek E. C. Broers; Jaap A. van Doesum; Rob S. van Binnendijk; Gerco den Hartog; Birgit I. Lissenberg-Witte; Arnon P. Kater; Gaby P. Smits; Dorine Wouters; Ester M. M. van Leeuwen; Hetty J. Bontkes; Neeltje A. Kootstra; Sandra Vogels-Nooijen; Debbie van Baarle; Rory D. de Vries; Tom van Meerten; Pim G. N. J. Mutsaers; Abraham Goorhuis; Inger S. Nijhof; Mette D. Hazenberg; Mirjam H. M. Heemskerk; Caroline E. Rutten; Cobra Kai Study Team

doi:10.3324/haematol.2024.287136

T-cell and antibody responses in immunocompromised patients with hematologic malignancies indicate strong potential of SARS-CoV-2 mRNA vaccines

Cilia R. Pothast
, Quincy Hofsink
, Sabine Haggenburg
, Romy C. Dijkland
, Marian van de Meent
, Kayleigh van Dijk
, Michel S. Bhoekhan
, Nienke J. E. Haverkate
, Johan van Meerloo
, J. H. Frederik Falkenburg
, Ruben A. L. de Groen
, Annoek E. C. Broers
, Jaap A. van Doesum
, Rob S. van Binnendijk
, Gerco den Hartog
, Birgit I. Lissenberg-Witte
, Arnon P. Kater
, Gaby P. Smits
, Dorine Wouters
, Ester M. M. van Leeuwen

Hetty J. Bontkes, Neeltje A. Kootstra, Sandra Vogels-Nooijen, Debbie van Baarle, Rory D. de Vries, Tom van Meerten, Pim G. N. J. Mutsaers, Abraham Goorhuis, Inger S. Nijhof, Mette D. Hazenberg, Mirjam H. M. Heemskerk, Caroline E. Rutten, Cobra Kai Study Team

Leiden University
University of Amsterdam
Amsterdam UMC
Erasmus University Rotterdam
University of Groningen
National Institute of Public Health and the Environment
Amsterdam UMC location Vrije Universiteit
Central Laboratory
Rogier Sanders

Research output: Contribution to journal › Article › Academic › peer-review

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Original language	English
Pages (from-to)	2799-2805
Number of pages	7
Journal	Haematologica
Volume	110
Issue number	11
DOIs	https://doi.org/10.3324/haematol.2024.287136
Publication status	Published - 1 Nov 2025

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SDG 3 Good Health and Well-being

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Pothast, C. R., Hofsink, Q., Haggenburg, S., Dijkland, R. C., van de Meent, M., van Dijk, K., Bhoekhan, M. S., Haverkate, N. J. E., van Meerloo, J., Falkenburg, J. H. F., de Groen, R. A. L., Broers, A. E. C., van Doesum, J. A., van Binnendijk, R. S., den Hartog, G., Lissenberg-Witte, B. I., Kater, A. P., Smits, G. P., Wouters, D., ... Study Team, C. K. (2025). T-cell and antibody responses in immunocompromised patients with hematologic malignancies indicate strong potential of SARS-CoV-2 mRNA vaccines. Haematologica, 110(11), 2799-2805. https://doi.org/10.3324/haematol.2024.287136

@article{51ea0749ed944f9f91c5ce9234028615,

title = "T-cell and antibody responses in immunocompromised patients with hematologic malignancies indicate strong potential of SARS-CoV-2 mRNA vaccines",

author = "Pothast, \{Cilia R.\} and Quincy Hofsink and Sabine Haggenburg and Dijkland, \{Romy C.\} and \{van de Meent\}, Marian and \{van Dijk\}, Kayleigh and Bhoekhan, \{Michel S.\} and Haverkate, \{Nienke J. E.\} and \{van Meerloo\}, Johan and Falkenburg, \{J. H. Frederik\} and \{de Groen\}, \{Ruben A. L.\} and Broers, \{Annoek E. C.\} and \{van Doesum\}, \{Jaap A.\} and \{van Binnendijk\}, \{Rob S.\} and \{den Hartog\}, Gerco and Lissenberg-Witte, \{Birgit I.\} and Kater, \{Arnon P.\} and Smits, \{Gaby P.\} and Dorine Wouters and \{van Leeuwen\}, \{Ester M. M.\} and Bontkes, \{Hetty J.\} and Kootstra, \{Neeltje A.\} and Sandra Vogels-Nooijen and \{van Baarle\}, Debbie and \{de Vries\}, \{Rory D.\} and \{van Meerten\}, Tom and Mutsaers, \{Pim G. N. J.\} and Abraham Goorhuis and Nijhof, \{Inger S.\} and Hazenberg, \{Mette D.\} and Heemskerk, \{Mirjam H. M.\} and Rutten, \{Caroline E.\} and \{Study Team\}, \{Cobra Kai\}",

year = "2025",

month = nov,

day = "1",

doi = "10.3324/haematol.2024.287136",

language = "English",

volume = "110",

pages = "2799--2805",

journal = "Haematologica",

issn = "0390-6078",

publisher = "Ferrata Storti Foundation",

number = "11",

}

Pothast, CR, Hofsink, Q , Haggenburg, S, Dijkland, RC, van de Meent, M, van Dijk, K, Bhoekhan, MS , Haverkate, NJE, van Meerloo, J, Falkenburg, JHF, de Groen, RAL, Broers, AEC, van Doesum, JA, van Binnendijk, RS, den Hartog, G, Lissenberg-Witte, BI , Kater, AP, Smits, GP, Wouters, D , van Leeuwen, EMM , Bontkes, HJ , Kootstra, NA, Vogels-Nooijen, S, van Baarle, D, de Vries, RD, van Meerten, T, Mutsaers, PGNJ, Goorhuis, A , Nijhof, IS , Hazenberg, MD, Heemskerk, MHM, Rutten, CE & Study Team, CK 2025, 'T-cell and antibody responses in immunocompromised patients with hematologic malignancies indicate strong potential of SARS-CoV-2 mRNA vaccines', Haematologica, vol. 110, no. 11, pp. 2799-2805. https://doi.org/10.3324/haematol.2024.287136

TY - JOUR

T1 - T-cell and antibody responses in immunocompromised patients with hematologic malignancies indicate strong potential of SARS-CoV-2 mRNA vaccines

AU - Pothast, Cilia R.

AU - Hofsink, Quincy

AU - Haggenburg, Sabine

AU - Dijkland, Romy C.

AU - van de Meent, Marian

AU - van Dijk, Kayleigh

AU - Bhoekhan, Michel S.

AU - Haverkate, Nienke J. E.

AU - van Meerloo, Johan

AU - Falkenburg, J. H. Frederik

AU - de Groen, Ruben A. L.

AU - Broers, Annoek E. C.

AU - van Doesum, Jaap A.

AU - van Binnendijk, Rob S.

AU - den Hartog, Gerco

AU - Lissenberg-Witte, Birgit I.

AU - Kater, Arnon P.

AU - Smits, Gaby P.

AU - Wouters, Dorine

AU - van Leeuwen, Ester M. M.

AU - Bontkes, Hetty J.

AU - Kootstra, Neeltje A.

AU - Vogels-Nooijen, Sandra

AU - van Baarle, Debbie

AU - de Vries, Rory D.

AU - van Meerten, Tom

AU - Mutsaers, Pim G. N. J.

AU - Goorhuis, Abraham

AU - Nijhof, Inger S.

AU - Hazenberg, Mette D.

AU - Heemskerk, Mirjam H. M.

AU - Rutten, Caroline E.

AU - Study Team, Cobra Kai

PY - 2025/11/1

Y1 - 2025/11/1

UR - https://www.scopus.com/pages/publications/105020819589

U2 - 10.3324/haematol.2024.287136

DO - 10.3324/haematol.2024.287136

M3 - Article

C2 - 40438989

SN - 0390-6078

VL - 110

SP - 2799

EP - 2805

JO - Haematologica

JF - Haematologica

IS - 11

ER -

T-cell and antibody responses in immunocompromised patients with hematologic malignancies indicate strong potential of SARS-CoV-2 mRNA vaccines

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