Stepping stones to targeted treatment of primary hyperoxaluria

L.J. Deesker

Stepping stones to targeted treatment of primary hyperoxaluria

L.J. Deesker

Research output: PhD Thesis › Phd-Thesis - Research and graduation internal

Abstract

The primary hyperoxalurias (PHs) are a group of rare genetic disorders affecting glyoxylate metabolism, leading to excessive oxalate production, a metabolic end-product. This overproduction can result in nephrocalcinosis, recurrent kidney stone formation and kidney failure. The clinical course of PH is highly variable, ranging from patients developing kidney failure in infancy to

Original language	English
Qualification	Doctor of Philosophy
Awarding Institution	University of Amsterdam
Supervisors/Advisors	Groothoff, Jaap, Supervisor Oosterveld, Michiel, Co-supervisor Garrelfs, Sander, Co-supervisor
Award date	2 May 2025
Print ISBNs	9789465221656
Publication status	Published - 2025

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https://hdl.handle.net/11245.1/1a8efd42-6bb1-4d7d-bd74-c8abeca1be25

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M3 - Phd-Thesis - Research and graduation internal

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Stepping stones to targeted treatment of primary hyperoxaluria

Abstract

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