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Staging, Functioning, and Cognition

  • Ralph Kupka*
  • , Jan Scott
  • , Manon Hillegers
  • *Corresponding author for this work
  • Newcastle University
  • Erasmus University Rotterdam

Research output: Chapter in Book/Report/Conference proceedingChapterAcademicpeer-review

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Abstract

Staging models in medicine aim to delineate disease progression and help choose effective treatments and make a reliable prognosis. In psychiatry, staging is still preliminary, given the difficult delineation between disorders and the lack of known pathophysiological underpinnings. Still, trans-diagnostic as well as disorder-specific staging models for illness progression in psychiatry have been proposed. This chapter presents the state of the art with regard to staging models of bipolar disorder and the clinical and research evidence for episode recurrence, inter-episodic functional impairment, and cognitive dysfunction as determinants of illness progression.
Original languageEnglish
Title of host publicationBipolar Disorder
Subtitle of host publicationAn Evidence-Based Clinical Guide
PublisherSpringer Science+Business Media
Pages211-229
Number of pages19
ISBN (Electronic)9783031855191
ISBN (Print)9783031855184
DOIs
Publication statusPublished - 1 Jan 2025

Publication series

NameBipolar Disorder: An Evidence-Based Clinical Guide

Keywords

  • Bipolar disorder
  • Clinical staging
  • Cognition
  • Functional impairment
  • Illness progression

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