Spermatogonial stem cells

D. G. de rooij; J. A. Grootegoed

doi:10.1016/S0955-0674(98)80109-9

Spermatogonial stem cells

D. G. de rooij
, J. A. Grootegoed

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

The mammalian seminiferous epithelium consists of a highly complex yet well-organized cell population, with germ cells in mitosis and meiosis and postmeiotic cells undergoing transformation to become spermatozoa. To study the factors which control renewal and differentiation of spermatogonial stem cells, animal models are now available which allow for arrest and restart of spermatogonial differentiation. In addition, marked progress has been made in understanding the control of apoptosis and its role in spermatogonia. For the future, spermatogonial stem cell transplantation may have important practical applications

Original language	English
Pages (from-to)	694-701
Journal	Current opinion in cell biology
Volume	10
Issue number	6
DOIs	https://doi.org/10.1016/S0955-0674(98)80109-9
Publication status	Published - 1998

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title = "Spermatogonial stem cells",

abstract = "The mammalian seminiferous epithelium consists of a highly complex yet well-organized cell population, with germ cells in mitosis and meiosis and postmeiotic cells undergoing transformation to become spermatozoa. To study the factors which control renewal and differentiation of spermatogonial stem cells, animal models are now available which allow for arrest and restart of spermatogonial differentiation. In addition, marked progress has been made in understanding the control of apoptosis and its role in spermatogonia. For the future, spermatogonial stem cell transplantation may have important practical applications",

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AU - Grootegoed, J. A.

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AB - The mammalian seminiferous epithelium consists of a highly complex yet well-organized cell population, with germ cells in mitosis and meiosis and postmeiotic cells undergoing transformation to become spermatozoa. To study the factors which control renewal and differentiation of spermatogonial stem cells, animal models are now available which allow for arrest and restart of spermatogonial differentiation. In addition, marked progress has been made in understanding the control of apoptosis and its role in spermatogonia. For the future, spermatogonial stem cell transplantation may have important practical applications

U2 - 10.1016/S0955-0674(98)80109-9

DO - 10.1016/S0955-0674(98)80109-9

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SN - 0955-0674

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SP - 694

EP - 701

JO - Current opinion in cell biology

JF - Current opinion in cell biology

IS - 6

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Spermatogonial stem cells

Abstract

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