Spatiotemporal Evolution of SARS-CoV-2 Alpha and Delta Variants during Large Nationwide Outbreak of COVID-19, Vietnam, 2021

OUCRU-NP COVID-19 research group; OUCRU COVID-19 Research Groups; HTD COVID-19 research group; EOCRU COVID-19 research group

doi:10.3201/eid2905.221787

Spatiotemporal Evolution of SARS-CoV-2 Alpha and Delta Variants during Large Nationwide Outbreak of COVID-19, Vietnam, 2021

OUCRU-NP COVID-19 research group
, OUCRU COVID-19 Research Groups
, HTD COVID-19 research group
, EOCRU COVID-19 research group

Emerging Infections Group, Oxford University Clinical Research Unit, Ho Chi Minh city, Vietnam
University College London Hospitals, London, UK
National Hospital for Tropical Diseases Hanoi, Vietnam
Vietnam Military Medical University
National Institute of Hygiene and Epidemiology, Hanoi, Vietnam
Hue Central Hospital
Da Nang Center for Disease Control
Nha Trang Pasteur Institute
Ho Chi Minh City Center for Disease Control
University of Oxford
Oxford University

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

We analyzed 1,303 SARS-CoV-2 whole-genome sequences from Vietnam, and found the Alpha and Delta variants were responsible for a large nationwide outbreak of COVID-19 in 2021. The Delta variant was confined to the AY.57 lineage and caused >1.7 million infections and >32,000 deaths. Viral transmission was strongly affected by nonpharmaceutical interventions.

Original language	English
Pages (from-to)	1002-1006
Number of pages	5
Journal	Emerging infectious diseases
Volume	29
Issue number	5
DOIs	https://doi.org/10.3201/eid2905.221787
Publication status	Published - 1 May 2023
Externally published	Yes

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

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10.3201/eid2905.221787

Cite this

@article{fcca42a01352433895506ed555ca6686,

title = "Spatiotemporal Evolution of SARS-CoV-2 Alpha and Delta Variants during Large Nationwide Outbreak of COVID-19, Vietnam, 2021",

abstract = "We analyzed 1,303 SARS-CoV-2 whole-genome sequences from Vietnam, and found the Alpha and Delta variants were responsible for a large nationwide outbreak of COVID-19 in 2021. The Delta variant was confined to the AY.57 lineage and caused >1.7 million infections and >32,000 deaths. Viral transmission was strongly affected by nonpharmaceutical interventions.",

author = "Tam, \{Nguyen Thi\} and Anh, \{Nguyen To\} and Tung, \{Trinh Son\} and Thach, \{Pham Ngoc\} and Dung, \{Nguyen Thanh\} and Trang, \{Van Dinh\} and Hung, \{Le Manh\} and Dien, \{Trinh Cong\} and Ngoc, \{Nghiem My\} and Duyet, \{Le Van\} and Cuong, \{Phan Manh\} and Phuong, \{Hoang Vu Mai\} and Thai, \{Pham Quang\} and Tung, \{Nguyen Le Nhu\} and Man, \{Dinh Nguyen Huy\} and Phong, \{Nguyen Thanh\} and Quang, \{Vo Minh\} and Thoa, \{Pham Thi Ngoc\} and Truong, \{Nguyen Thanh\} and Thao, \{Tran Nguyen Phuong\} and Linh, \{Dao Phuong\} and Tai, \{Ngo Tan\} and Bao, \{Ho The\} and Vuong, \{Vo Trong\} and \{OUCRU-NP COVID-19 research group\} and Nhung, \{Huynh Thi Kim\} and Hong, \{Phan Nu Dieu\} and Hanh, \{Le Thi Phuoc\} and Chung, \{Le Thanh\} and Nhan, \{Nguyen Thi Thanh\} and Thanh, \{Ton That\} and Hung, \{Do Thai\} and Mai, \{Huynh Kim\} and Long, \{Trinh Hoang\} and Trang, \{Nguyen Thu\} and Thuong, \{Nguyen Thi Hong\} and Hong, \{Nguyen Thi Thu\} and Nhu, \{Le Nguyen Truc\} and Ny, \{Nguyen Thi Han\} and Thuy, \{Cao Thu\} and Thanh, \{Le Kim\} and Nguyet, \{Lam Anh\} and Mai, \{Le Thi Quynh\} and \{OUCRU COVID-19 Research Groups\} and Thuong, \{Tang Chi\} and \{HTD COVID-19 research group\} and Nga, \{Le Hong\} and Thanh, \{Tran Tan\} and \{EOCRU COVID-19 research group\} and Guy Thwaites and \{van Doorn\}, \{H. Rogier\} and Chau, \{Nguyen Van Vinh\} and Thomas Kesteman and Tan, \{Le Van\} and Mary Chambers and Marc Choisy and Trinh, \{Dong Huu Khanh\} and Tam, \{Dong Thi Hoai\} and Duc, \{Du Hong\} and Viet, \{Dung Vu Tien\} and Jaom Fisher and Barney Flower and Ronald Geskus and Kim, \{Hang Vu Thi\} and Chanh, \{Ho Quang\} and Hai, \{Ho Thi Bich\} and Hien, \{Ho Van\} and Bao, \{Hung Vu\} and Thao, \{Huong Dang\} and Huy, \{Huynh Le Anh\} and Ha, \{Huynh Ngan\} and Trieu, \{Huynh Trung\} and Yen, \{Huynh Xuan\} and Evelyne Kestelyn and Katrina Lawson and Leigh Jones and Khoa, \{Le Dinh Van\} and Nhat, \{Le Thanh Hoang\} and Lewycka, \{Sonia Odette\} and Yen, \{Lam Minh\} and Lan, \{Le Thi Hoang\} and Nguyen, \{Nam Vinh\} and Hoa, \{Ngo Thi\} and Tran, \{Nguyen Bao\} and Manh, \{Nguyen Duc\} and Yen, \{Nguyen Hoang\} and My, \{Nguyen Le Thao\} and Nguyet, \{Nguyen Minh\} and Ha, \{Nguyen Thanh\} and Quyen, \{Nguyen Than Ha\} and Ngoc, \{Nguyen Thanh\} and Nhien, \{Nguyen Thanh Thuy\} and Yen, \{Nguyen Thi Hong\} and Trang, \{Nguyen Thi Huyen\} and Ngoc, \{Nguyen Thi Kim\} and Tuyen, \{Nguyen Thi Kim\} and Diep, \{Nguyen Thi Ngoc\} and Dung, \{Nguyen Thi Phuong\} and Thuong, \{Nguyen Thuy Thuong\} and Truong, \{Nguyen Xuan\} and Phuong, \{Nhung Doan\} and van, \{Ninh Thi Thanh\} and Thinh, \{Ong Phuc\} and Thanh, \{Pham Ngoc\} and Khanh, \{Phan Nguyen Quoc\} and Kim, \{Phung Ho Thi\} and Lam, \{Phung Khanh\} and Yen, \{Phung Le Kim\} and Nhat, \{Phung Tran Huy\} and Motiur Rahman and Huyen, \{Thuong Nguyen Thi\} and Louise Thwaites and Huyen, \{Tran Bang\} and Han, \{Tran Dong Thai\} and Anh, \{Tran Kim Van\} and Hien, \{Tran Minh\} and Thao, \{Tran Phuong\} and Ngoc, \{Tran Thi Bich\} and Hang, \{Tran Thi\} and Hien, \{Tran Tinh\} and Nuil, \{Jennifer Van\} and Vidaillac, \{Celine Pascale\} and Bich, \{Vu Thi Ngoc\} and Hang, \{Vu Thi Ty\} and Sophie Yacoub and Loan, \{Huynh Thi\} and Hao, \{Nguyen Van\} and Thuy, \{Duong Bich\} and Lan, \{Nguyen Phu Huong\} and Phuong, \{Tran Thi Lan\} and Uyen, \{Le Thi Tam\} and Tam, \{Tran Thi Thanh\} and That, \{Bui Thi Ton\} and Nhung, \{Huynh Kim\} and Tu, \{Tran Nguyen Hoang\} and Ty, \{Dinh Thi Bich\} and Dung, \{Le Thi\} and Uyen, \{Thai Lam\} and Tien, \{Nguyen Thi My\} and Thao, \{Ho Thi Thu\} and Thao, \{Nguyen Ngoc\} and Vuong, \{Huynh Ngoc Thien\} and Thao, \{Pham Ngoc Phuong\} and Phuong, \{Phan Minh\} and Andy Bachtiar and Baird, \{J. Kevin\} and Fitri Dewi and Ragil Dien and Djaafara, \{Bimandra A.\} and Elyazar, \{Iqbal E.\} and Hamers, \{Raph H.\} and Winahyu Handayani and Kurniawan, \{Livia N.\} and Ralalicia Limato and Cindy Natasha and Nunung Nuraeni and Khairunisa Puspatriani and Mutia Rahadjani and Atika Rimainar and Saraswati Shankar and H. Anuraj and Henry Suhendra and Ida Sutrisni and Ayu Suwarti and Nicolas Tarino and Diana Timoria and Fitri Wulandari and Buddha Basnyat and Manish Duwal and Amit Gautum and Abhilasha Karkey and Niharika Kharel and Aakriti Pandey and Samia Rijal and Suchita Shrestha and Pratibha Thapa and Summita Udas",

note = "Funding Information: Genomic surveillance was supported by the Wellcome Trust (222574/Z/21/Z). L.V.T. and G.T. are supported by the Wellcome Trust of Great Britain (204904/Z/16/Z and 106680/B/14/Z, respectively). Publisher Copyright: {\textcopyright} 2023 Centers for Disease Control and Prevention (CDC). All rights reserved.",

year = "2023",

month = may,

day = "1",

doi = "10.3201/eid2905.221787",

language = "English",

volume = "29",

pages = "1002--1006",

journal = "Emerging infectious diseases",

issn = "1080-6040",

publisher = "Centers for Disease Control and Prevention (CDC)",

number = "5",

}

Spatiotemporal Evolution of SARS-CoV-2 Alpha and Delta Variants during Large Nationwide Outbreak of COVID-19, Vietnam, 2021. / OUCRU-NP COVID-19 research group; OUCRU COVID-19 Research Groups; HTD COVID-19 research group et al.
In: Emerging infectious diseases, Vol. 29, No. 5, 01.05.2023, p. 1002-1006.

Research output: Contribution to journal › Article › Academic › peer-review

TY - JOUR

T1 - Spatiotemporal Evolution of SARS-CoV-2 Alpha and Delta Variants during Large Nationwide Outbreak of COVID-19, Vietnam, 2021

AU - Tam, Nguyen Thi

AU - Anh, Nguyen To

AU - Tung, Trinh Son

AU - Thach, Pham Ngoc

AU - Dung, Nguyen Thanh

AU - Trang, Van Dinh

AU - Hung, Le Manh

AU - Dien, Trinh Cong

AU - Ngoc, Nghiem My

AU - Duyet, Le Van

AU - Cuong, Phan Manh

AU - Phuong, Hoang Vu Mai

AU - Thai, Pham Quang

AU - Tung, Nguyen Le Nhu

AU - Man, Dinh Nguyen Huy

AU - Phong, Nguyen Thanh

AU - Quang, Vo Minh

AU - Thoa, Pham Thi Ngoc

AU - Truong, Nguyen Thanh

AU - Thao, Tran Nguyen Phuong

AU - Linh, Dao Phuong

AU - Tai, Ngo Tan

AU - Bao, Ho The

AU - Vuong, Vo Trong

AU - OUCRU-NP COVID-19 research group

AU - Nhung, Huynh Thi Kim

AU - Hong, Phan Nu Dieu

AU - Hanh, Le Thi Phuoc

AU - Chung, Le Thanh

AU - Nhan, Nguyen Thi Thanh

AU - Thanh, Ton That

AU - Hung, Do Thai

AU - Mai, Huynh Kim

AU - Long, Trinh Hoang

AU - Trang, Nguyen Thu

AU - Thuong, Nguyen Thi Hong

AU - Hong, Nguyen Thi Thu

AU - Nhu, Le Nguyen Truc

AU - Ny, Nguyen Thi Han

AU - Thuy, Cao Thu

AU - Thanh, Le Kim

AU - Nguyet, Lam Anh

AU - Mai, Le Thi Quynh

AU - OUCRU COVID-19 Research Groups

AU - Thuong, Tang Chi

AU - HTD COVID-19 research group

AU - Nga, Le Hong

AU - Thanh, Tran Tan

AU - EOCRU COVID-19 research group

AU - Thwaites, Guy

AU - van Doorn, H. Rogier

AU - Chau, Nguyen Van Vinh

AU - Kesteman, Thomas

AU - Tan, Le Van

AU - Chambers, Mary

AU - Choisy, Marc

AU - Trinh, Dong Huu Khanh

AU - Tam, Dong Thi Hoai

AU - Duc, Du Hong

AU - Viet, Dung Vu Tien

AU - Fisher, Jaom

AU - Flower, Barney

AU - Geskus, Ronald

AU - Kim, Hang Vu Thi

AU - Chanh, Ho Quang

AU - Hai, Ho Thi Bich

AU - Hien, Ho Van

AU - Bao, Hung Vu

AU - Thao, Huong Dang

AU - Huy, Huynh Le Anh

AU - Ha, Huynh Ngan

AU - Trieu, Huynh Trung

AU - Yen, Huynh Xuan

AU - Kestelyn, Evelyne

AU - Lawson, Katrina

AU - Jones, Leigh

AU - Khoa, Le Dinh Van

AU - Nhat, Le Thanh Hoang

AU - Lewycka, Sonia Odette

AU - Yen, Lam Minh

AU - Lan, Le Thi Hoang

AU - Nguyen, Nam Vinh

AU - Hoa, Ngo Thi

AU - Tran, Nguyen Bao

AU - Manh, Nguyen Duc

AU - Yen, Nguyen Hoang

AU - My, Nguyen Le Thao

AU - Nguyet, Nguyen Minh

AU - Ha, Nguyen Thanh

AU - Quyen, Nguyen Than Ha

AU - Ngoc, Nguyen Thanh

AU - Nhien, Nguyen Thanh Thuy

AU - Yen, Nguyen Thi Hong

AU - Trang, Nguyen Thi Huyen

AU - Ngoc, Nguyen Thi Kim

AU - Tuyen, Nguyen Thi Kim

AU - Diep, Nguyen Thi Ngoc

AU - Dung, Nguyen Thi Phuong

AU - Thuong, Nguyen Thuy Thuong

AU - Truong, Nguyen Xuan

AU - Phuong, Nhung Doan

AU - van, Ninh Thi Thanh

AU - Thinh, Ong Phuc

AU - Thanh, Pham Ngoc

AU - Khanh, Phan Nguyen Quoc

AU - Kim, Phung Ho Thi

AU - Lam, Phung Khanh

AU - Yen, Phung Le Kim

AU - Nhat, Phung Tran Huy

AU - Rahman, Motiur

AU - Huyen, Thuong Nguyen Thi

AU - Thwaites, Louise

AU - Huyen, Tran Bang

AU - Han, Tran Dong Thai

AU - Anh, Tran Kim Van

AU - Hien, Tran Minh

AU - Thao, Tran Phuong

AU - Ngoc, Tran Thi Bich

AU - Hang, Tran Thi

AU - Hien, Tran Tinh

AU - Nuil, Jennifer Van

AU - Vidaillac, Celine Pascale

AU - Bich, Vu Thi Ngoc

AU - Hang, Vu Thi Ty

AU - Yacoub, Sophie

AU - Loan, Huynh Thi

AU - Hao, Nguyen Van

AU - Thuy, Duong Bich

AU - Lan, Nguyen Phu Huong

AU - Phuong, Tran Thi Lan

AU - Uyen, Le Thi Tam

AU - Tam, Tran Thi Thanh

AU - That, Bui Thi Ton

AU - Nhung, Huynh Kim

AU - Tu, Tran Nguyen Hoang

AU - Ty, Dinh Thi Bich

AU - Dung, Le Thi

AU - Uyen, Thai Lam

AU - Tien, Nguyen Thi My

AU - Thao, Ho Thi Thu

AU - Thao, Nguyen Ngoc

AU - Vuong, Huynh Ngoc Thien

AU - Thao, Pham Ngoc Phuong

AU - Phuong, Phan Minh

AU - Bachtiar, Andy

AU - Baird, J. Kevin

AU - Dewi, Fitri

AU - Dien, Ragil

AU - Djaafara, Bimandra A.

AU - Elyazar, Iqbal E.

AU - Hamers, Raph H.

AU - Handayani, Winahyu

AU - Kurniawan, Livia N.

AU - Limato, Ralalicia

AU - Natasha, Cindy

AU - Nuraeni, Nunung

AU - Puspatriani, Khairunisa

AU - Rahadjani, Mutia

AU - Rimainar, Atika

AU - Shankar, Saraswati

AU - Anuraj, H.

AU - Suhendra, Henry

AU - Sutrisni, Ida

AU - Suwarti, Ayu

AU - Tarino, Nicolas

AU - Timoria, Diana

AU - Wulandari, Fitri

AU - Basnyat, Buddha

AU - Duwal, Manish

AU - Gautum, Amit

AU - Karkey, Abhilasha

AU - Kharel, Niharika

AU - Pandey, Aakriti

AU - Rijal, Samia

AU - Shrestha, Suchita

AU - Thapa, Pratibha

AU - Udas, Summita

N1 - Funding Information: Genomic surveillance was supported by the Wellcome Trust (222574/Z/21/Z). L.V.T. and G.T. are supported by the Wellcome Trust of Great Britain (204904/Z/16/Z and 106680/B/14/Z, respectively). Publisher Copyright: © 2023 Centers for Disease Control and Prevention (CDC). All rights reserved.

PY - 2023/5/1

Y1 - 2023/5/1

N2 - We analyzed 1,303 SARS-CoV-2 whole-genome sequences from Vietnam, and found the Alpha and Delta variants were responsible for a large nationwide outbreak of COVID-19 in 2021. The Delta variant was confined to the AY.57 lineage and caused >1.7 million infections and >32,000 deaths. Viral transmission was strongly affected by nonpharmaceutical interventions.

AB - We analyzed 1,303 SARS-CoV-2 whole-genome sequences from Vietnam, and found the Alpha and Delta variants were responsible for a large nationwide outbreak of COVID-19 in 2021. The Delta variant was confined to the AY.57 lineage and caused >1.7 million infections and >32,000 deaths. Viral transmission was strongly affected by nonpharmaceutical interventions.

UR - https://www.scopus.com/pages/publications/85153122197

U2 - 10.3201/eid2905.221787

DO - 10.3201/eid2905.221787

M3 - Article

C2 - 37015283

SN - 1080-6040

VL - 29

SP - 1002

EP - 1006

JO - Emerging infectious diseases

JF - Emerging infectious diseases

IS - 5

ER -

Spatiotemporal Evolution of SARS-CoV-2 Alpha and Delta Variants during Large Nationwide Outbreak of COVID-19, Vietnam, 2021

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