SARS-CoV-2-specific CD8+ T cell responses in healthy and immunocompromised individuals

J. van den Dijssel

SARS-CoV-2-specific CD8+ T cell responses in healthy and immunocompromised individuals

J. van den Dijssel

Research output: PhD Thesis › Phd-Thesis - Research and graduation internal

Abstract

CD8⁺ T cells are essential for antiviral immunity, reducing disease severity by recognizing and targeting a broad range of virus-derived epitopes. This thesis identified highly conserved SARS-CoV-2-specific CD8⁺ T cell epitopes to study the role of CD8⁺ T cells in healthy and immunocompromised individuals. SARS-CoV-2 infection induced robust virus-specific CD8⁺ T cell responses exhibiting a

Original language	English
Qualification	Doctor of Philosophy
Awarding Institution	University of Amsterdam
Supervisors/Advisors	van Lier, Rene, Supervisor van de Sandt, Carolien E., Co-supervisor, External person van Gisbergen, Klaas, Co-supervisor
Award date	10 Jul 2025
Print ISBNs	9789465223674
Publication status	Published - 2025

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Access to Document

https://pure.uva.nl/ws/files/238158686/Thesis.pdf

Cite this

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title = "SARS-CoV-2-specific CD8+ T cell responses in healthy and immunocompromised individuals",

abstract = "CD8⁺ T cells are essential for antiviral immunity, reducing disease severity by recognizing and targeting a broad range of virus-derived epitopes. This thesis identified highly conserved SARS-CoV-2-specific CD8⁺ T cell epitopes to study the role of CD8⁺ T cells in healthy and immunocompromised individuals. SARS-CoV-2 infection induced robust virus-specific CD8⁺ T cell responses exhibiting a",

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AB - CD8⁺ T cells are essential for antiviral immunity, reducing disease severity by recognizing and targeting a broad range of virus-derived epitopes. This thesis identified highly conserved SARS-CoV-2-specific CD8⁺ T cell epitopes to study the role of CD8⁺ T cells in healthy and immunocompromised individuals. SARS-CoV-2 infection induced robust virus-specific CD8⁺ T cell responses exhibiting a

M3 - Phd-Thesis - Research and graduation internal

SN - 9789465223674

ER -

SARS-CoV-2-specific CD8+ T cell responses in healthy and immunocompromised individuals

Abstract

UN SDGs

Access to Document

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Cite this