Role of Polyethylene Glycol in the Treatment of Functional Constipation in Children

Ilan J. N. Koppen; Ilse J. Broekaert; Michael Wilschanski; Alexandra Papadopoulou; Carmen Ribes-Koninckx; Nikhil Thapar; Frederic Gottrand; Rok Orel; Paolo Lionetti; Marc A. Benninga

doi:10.1097/MPG.0000000000001704

Role of Polyethylene Glycol in the Treatment of Functional Constipation in Children

Ilan J. N. Koppen
, Ilse J. Broekaert
, Michael Wilschanski
, Alexandra Papadopoulou
, Carmen Ribes-Koninckx
, Nikhil Thapar
, Frederic Gottrand
, Rok Orel
, Paolo Lionetti
, Marc A. Benninga

Research output: Contribution to journal › Article › Academic › peer-review

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Abstract

According to international guidelines, polyethylene glycol (PEG) is the laxative of first choice in the treatment of functional constipation in children, both for disimpaction and for maintenance treatment. PEG acts as an osmotic laxative and its efficacy is dose dependent. PEG is highly effective, has a good safety profile, and is well tolerated by children. Only minor adverse events have been reported. Overall the use of PEG in children has been reported to be safe, although in patients predisposed to water and electrolyte imbalances monitoring of serum electrolytes should be considered

Original language	English
Pages (from-to)	361-363
Journal	Journal of pediatric gastroenterology and nutrition
Volume	65
Issue number	4
Early online date	2017
DOIs	https://doi.org/10.1097/MPG.0000000000001704
Publication status	Published - 2017

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title = "Role of Polyethylene Glycol in the Treatment of Functional Constipation in Children",

abstract = "According to international guidelines, polyethylene glycol (PEG) is the laxative of first choice in the treatment of functional constipation in children, both for disimpaction and for maintenance treatment. PEG acts as an osmotic laxative and its efficacy is dose dependent. PEG is highly effective, has a good safety profile, and is well tolerated by children. Only minor adverse events have been reported. Overall the use of PEG in children has been reported to be safe, although in patients predisposed to water and electrolyte imbalances monitoring of serum electrolytes should be considered",

author = "Koppen, \{Ilan J. N.\} and Broekaert, \{Ilse J.\} and Michael Wilschanski and Alexandra Papadopoulou and Carmen Ribes-Koninckx and Nikhil Thapar and Frederic Gottrand and Rok Orel and Paolo Lionetti and Benninga, \{Marc A.\}",

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doi = "10.1097/MPG.0000000000001704",

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AU - Koppen, Ilan J. N.

AU - Broekaert, Ilse J.

AU - Wilschanski, Michael

AU - Papadopoulou, Alexandra

AU - Ribes-Koninckx, Carmen

AU - Thapar, Nikhil

AU - Gottrand, Frederic

AU - Orel, Rok

AU - Lionetti, Paolo

AU - Benninga, Marc A.

PY - 2017

Y1 - 2017

N2 - According to international guidelines, polyethylene glycol (PEG) is the laxative of first choice in the treatment of functional constipation in children, both for disimpaction and for maintenance treatment. PEG acts as an osmotic laxative and its efficacy is dose dependent. PEG is highly effective, has a good safety profile, and is well tolerated by children. Only minor adverse events have been reported. Overall the use of PEG in children has been reported to be safe, although in patients predisposed to water and electrolyte imbalances monitoring of serum electrolytes should be considered

AB - According to international guidelines, polyethylene glycol (PEG) is the laxative of first choice in the treatment of functional constipation in children, both for disimpaction and for maintenance treatment. PEG acts as an osmotic laxative and its efficacy is dose dependent. PEG is highly effective, has a good safety profile, and is well tolerated by children. Only minor adverse events have been reported. Overall the use of PEG in children has been reported to be safe, although in patients predisposed to water and electrolyte imbalances monitoring of serum electrolytes should be considered

U2 - 10.1097/MPG.0000000000001704

DO - 10.1097/MPG.0000000000001704

M3 - Article

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VL - 65

SP - 361

EP - 363

JO - Journal of pediatric gastroenterology and nutrition

JF - Journal of pediatric gastroenterology and nutrition

IS - 4

ER -

Role of Polyethylene Glycol in the Treatment of Functional Constipation in Children

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