Right ventricular pressure-volume loop analysis in congenital heart disease

Background Right ventricular (RV) function is an independent predictor of prognosis in patients with congenital heart disease (CHD). Early detection is therefore crucial but current methods to assess RV function are highly load-dependent. RV pressure-volume (PV) loop analysis is an invasive technique which is load-independent and considered the gold standard for evaluating RV adaptation in relation to its load. However, RV PV loop analysis can be time consuming and prone to inter-operator variability. Methods This article provides a comprehensive guide on performing RV PV loop analysis using the multi-beat method in pediatric and adult patients with complex CHD. Results RV PV loop analysis using the multi-beat method can be safely and reliably applied in children and adults with complex CHD. Conclusion RV PV loop analysis offers a valuable tool for advanced insight into RV adaptation and a deeper understanding of cardiac physiology in complex CHD patients with RV pressure and/or volume overload. By enhancing our understanding of RV adaptation, this approach holds great potential for improving patient management and optimizing treatment strategies.