Rational use of mucoactive medications to treat pediatric airway disease

R. S. N. Linssen; J. Ma; R. A. Bem; B. K. Rubin

doi:10.1016/j.prrv.2020.06.007

Rational use of mucoactive medications to treat pediatric airway disease

R. S. N. Linssen
, J. Ma
, R. A. Bem
, B. K. Rubin^*

^*Corresponding author for this work

University of Amsterdam
Virginia Commonwealth University

Research output: Contribution to journal › Review article › Academic › peer-review

Abstract

Many airway diseases in children, notably bronchiolitis, cystic fibrosis (CF), non-CF bronchiectasis including primary ciliary dyskinesia, pneumonia, and severe asthma are associated with retention of airway secretions. Medications to improve secretions clearance, the mucoactive medications, are employed to treat these diseases with varying degrees of success. This manuscript reviews evidence for the use of these medications and future directions of study.

Original language	English
Pages (from-to)	8-14
Number of pages	7
Journal	Paediatric respiratory reviews
Volume	36
Early online date	2020
DOIs	https://doi.org/10.1016/j.prrv.2020.06.007
Publication status	Published - Nov 2020

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Airway diseases
Cystic fibrosis
Dornase
Mucoactive medications
Mucolytics
Sputum

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10.1016/j.prrv.2020.06.007

Cite this

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title = "Rational use of mucoactive medications to treat pediatric airway disease",

abstract = "Many airway diseases in children, notably bronchiolitis, cystic fibrosis (CF), non-CF bronchiectasis including primary ciliary dyskinesia, pneumonia, and severe asthma are associated with retention of airway secretions. Medications to improve secretions clearance, the mucoactive medications, are employed to treat these diseases with varying degrees of success. This manuscript reviews evidence for the use of these medications and future directions of study.",

keywords = "Airway diseases, Cystic fibrosis, Dornase, Mucoactive medications, Mucolytics, Sputum",

author = "Linssen, \{R. S. N.\} and J. Ma and Bem, \{R. A.\} and Rubin, \{B. K.\}",

year = "2020",

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doi = "10.1016/j.prrv.2020.06.007",

language = "English",

volume = "36",

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AU - Linssen, R. S. N.

AU - Ma, J.

AU - Bem, R. A.

AU - Rubin, B. K.

PY - 2020/11

Y1 - 2020/11

N2 - Many airway diseases in children, notably bronchiolitis, cystic fibrosis (CF), non-CF bronchiectasis including primary ciliary dyskinesia, pneumonia, and severe asthma are associated with retention of airway secretions. Medications to improve secretions clearance, the mucoactive medications, are employed to treat these diseases with varying degrees of success. This manuscript reviews evidence for the use of these medications and future directions of study.

AB - Many airway diseases in children, notably bronchiolitis, cystic fibrosis (CF), non-CF bronchiectasis including primary ciliary dyskinesia, pneumonia, and severe asthma are associated with retention of airway secretions. Medications to improve secretions clearance, the mucoactive medications, are employed to treat these diseases with varying degrees of success. This manuscript reviews evidence for the use of these medications and future directions of study.

KW - Airway diseases

KW - Cystic fibrosis

KW - Dornase

KW - Mucoactive medications

KW - Mucolytics

KW - Sputum

UR - https://www.scopus.com/pages/publications/85087687558

U2 - 10.1016/j.prrv.2020.06.007

DO - 10.1016/j.prrv.2020.06.007

M3 - Review article

C2 - 32653467

SN - 1526-0542

VL - 36

SP - 8

EP - 14

JO - Paediatric respiratory reviews

JF - Paediatric respiratory reviews

ER -

Rational use of mucoactive medications to treat pediatric airway disease

Abstract

UN SDGs

Keywords

Access to Document

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