Psychological factors associated with the intention to choose for risk-reducing mastectomy in family cancer clinic attendees

C M G van Driel; J C Oosterwijk; E J Meijers-Heijboer; C J van Asperen; I A Zeijlmans van Emmichoven; J de Vries; M J E Mourits; L Henneman; D R M Timmermans; G H de Bock

doi:10.1016/j.breast.2016.08.016

Psychological factors associated with the intention to choose for risk-reducing mastectomy in family cancer clinic attendees

C M G van Driel
, J C Oosterwijk
, E J Meijers-Heijboer
, C J van Asperen
, I A Zeijlmans van Emmichoven
, J de Vries
, M J E Mourits
, L Henneman
, D R M Timmermans
, G H de Bock

Department of Obstetrics & Gynecology, University Medical Center Groningen, PO Box 30.001, 9700 RB Groningen, The Netherlands. Electronic address: [email protected].
Department of Clinical Genetics, Leiden University Medical Center, PO Box 9600, 2300 RC Leiden, The Netherlands.
Department of Medical Psychology, University Medical Center Groningen, PO Box 30.001, 9700 RB Groningen, The Netherlands.
Department of Obstetrics & Gynecology, University Medical Center Groningen, PO Box 30.001, 9700 RB Groningen, The Netherlands.
Department of Epidemiology, University Medical Center Groningen, PO Box 30.001, 9700 RB Groningen, The Netherlands.

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

OBJECTIVES: Women seeking counseling because of familial breast cancer occurrence face difficult decisions, such as whether and when to opt for risk-reducing mastectomy (RRM) in case of BRCA1/2 mutation. Only limited research has been done to identify the psychological factors associated with the decision for RRM. This study investigated which psychological factors are related to the intention to choose for RRM.

MATERIALS & METHODS: A cohort of 486 cancer-unaffected women with a family history of breast cancer completed the following questionnaires prior to genetic counseling: the Cancer Worry Scale, Positive And Negative Affect Scale, Perceived Personal Control Scale, Hospital Anxiety and Depression Scale and State Anxiety Scale and questions regarding socio-demographic characteristics, family history, risk perception and RRM intention. Multivariate logistic regression was used to analyze the relation between psychological factors and women's intention to choose for RRM.

RESULTS: Factors associated with RRM intention were high positive affect (OR = 1.86, 95%CI = 1.12-3.08), high negative affect (OR = 2.52, 95%CI = 1.44-4.43), high cancer worry (OR = 1.65, 95%CI = 1.00-2.72), high perceived personal control (OR = 3.58, 95%CI = 2.18-5.89), high risk-perception (OR = 1.85, 95%CI = 1.15-2.95) and having children (OR = 2.06, 95%CI = 1.21-3.50).

CONCLUSION: Negative and positive affects play an important role in the intention for RRM. Furthermore, perceived personal control over the situation is associated with an intention for RRM. In addition to focusing on accurate risk communication, counseling should pay attention to the influence of perceived control and emotions to facilitate decision-making.

Original language	English
Pages (from-to)	66-72
Number of pages	7
Journal	Breast
Volume	30
DOIs	https://doi.org/10.1016/j.breast.2016.08.016
Publication status	Published - Dec 2016

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SDG 3 Good Health and Well-being

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van Driel, C. M. G., Oosterwijk, J. C., Meijers-Heijboer, E. J., van Asperen, C. J., Zeijlmans van Emmichoven, I. A., de Vries, J., Mourits, M. J. E., Henneman, L., Timmermans, D. R. M., & de Bock, G. H. (2016). Psychological factors associated with the intention to choose for risk-reducing mastectomy in family cancer clinic attendees. Breast, 30, 66-72. https://doi.org/10.1016/j.breast.2016.08.016

@article{7569b6d4a75548a892978433d5047a1d,

title = "Psychological factors associated with the intention to choose for risk-reducing mastectomy in family cancer clinic attendees",

abstract = "OBJECTIVES: Women seeking counseling because of familial breast cancer occurrence face difficult decisions, such as whether and when to opt for risk-reducing mastectomy (RRM) in case of BRCA1/2 mutation. Only limited research has been done to identify the psychological factors associated with the decision for RRM. This study investigated which psychological factors are related to the intention to choose for RRM.MATERIALS \& METHODS: A cohort of 486 cancer-unaffected women with a family history of breast cancer completed the following questionnaires prior to genetic counseling: the Cancer Worry Scale, Positive And Negative Affect Scale, Perceived Personal Control Scale, Hospital Anxiety and Depression Scale and State Anxiety Scale and questions regarding socio-demographic characteristics, family history, risk perception and RRM intention. Multivariate logistic regression was used to analyze the relation between psychological factors and women's intention to choose for RRM.RESULTS: Factors associated with RRM intention were high positive affect (OR = 1.86, 95\%CI = 1.12-3.08), high negative affect (OR = 2.52, 95\%CI = 1.44-4.43), high cancer worry (OR = 1.65, 95\%CI = 1.00-2.72), high perceived personal control (OR = 3.58, 95\%CI = 2.18-5.89), high risk-perception (OR = 1.85, 95\%CI = 1.15-2.95) and having children (OR = 2.06, 95\%CI = 1.21-3.50).CONCLUSION: Negative and positive affects play an important role in the intention for RRM. Furthermore, perceived personal control over the situation is associated with an intention for RRM. In addition to focusing on accurate risk communication, counseling should pay attention to the influence of perceived control and emotions to facilitate decision-making.",

author = "\{van Driel\}, \{C M G\} and Oosterwijk, \{J C\} and Meijers-Heijboer, \{E J\} and \{van Asperen\}, \{C J\} and \{Zeijlmans van Emmichoven\}, \{I A\} and \{de Vries\}, J and Mourits, \{M J E\} and L Henneman and Timmermans, \{D R M\} and \{de Bock\}, \{G H\}",

year = "2016",

month = dec,

doi = "10.1016/j.breast.2016.08.016",

language = "English",

volume = "30",

pages = "66--72",

journal = "Breast",

issn = "0960-9776",

publisher = "Churchill Livingstone",

}

van Driel, CMG, Oosterwijk, JC, Meijers-Heijboer, EJ, van Asperen, CJ, Zeijlmans van Emmichoven, IA, de Vries, J, Mourits, MJE, Henneman, L , Timmermans, DRM & de Bock, GH 2016, 'Psychological factors associated with the intention to choose for risk-reducing mastectomy in family cancer clinic attendees', Breast, vol. 30, pp. 66-72. https://doi.org/10.1016/j.breast.2016.08.016

TY - JOUR

T1 - Psychological factors associated with the intention to choose for risk-reducing mastectomy in family cancer clinic attendees

AU - van Driel, C M G

AU - Oosterwijk, J C

AU - Meijers-Heijboer, E J

AU - van Asperen, C J

AU - Zeijlmans van Emmichoven, I A

AU - de Vries, J

AU - Mourits, M J E

AU - Henneman, L

AU - Timmermans, D R M

AU - de Bock, G H

PY - 2016/12

Y1 - 2016/12

N2 - OBJECTIVES: Women seeking counseling because of familial breast cancer occurrence face difficult decisions, such as whether and when to opt for risk-reducing mastectomy (RRM) in case of BRCA1/2 mutation. Only limited research has been done to identify the psychological factors associated with the decision for RRM. This study investigated which psychological factors are related to the intention to choose for RRM.MATERIALS & METHODS: A cohort of 486 cancer-unaffected women with a family history of breast cancer completed the following questionnaires prior to genetic counseling: the Cancer Worry Scale, Positive And Negative Affect Scale, Perceived Personal Control Scale, Hospital Anxiety and Depression Scale and State Anxiety Scale and questions regarding socio-demographic characteristics, family history, risk perception and RRM intention. Multivariate logistic regression was used to analyze the relation between psychological factors and women's intention to choose for RRM.RESULTS: Factors associated with RRM intention were high positive affect (OR = 1.86, 95%CI = 1.12-3.08), high negative affect (OR = 2.52, 95%CI = 1.44-4.43), high cancer worry (OR = 1.65, 95%CI = 1.00-2.72), high perceived personal control (OR = 3.58, 95%CI = 2.18-5.89), high risk-perception (OR = 1.85, 95%CI = 1.15-2.95) and having children (OR = 2.06, 95%CI = 1.21-3.50).CONCLUSION: Negative and positive affects play an important role in the intention for RRM. Furthermore, perceived personal control over the situation is associated with an intention for RRM. In addition to focusing on accurate risk communication, counseling should pay attention to the influence of perceived control and emotions to facilitate decision-making.

AB - OBJECTIVES: Women seeking counseling because of familial breast cancer occurrence face difficult decisions, such as whether and when to opt for risk-reducing mastectomy (RRM) in case of BRCA1/2 mutation. Only limited research has been done to identify the psychological factors associated with the decision for RRM. This study investigated which psychological factors are related to the intention to choose for RRM.MATERIALS & METHODS: A cohort of 486 cancer-unaffected women with a family history of breast cancer completed the following questionnaires prior to genetic counseling: the Cancer Worry Scale, Positive And Negative Affect Scale, Perceived Personal Control Scale, Hospital Anxiety and Depression Scale and State Anxiety Scale and questions regarding socio-demographic characteristics, family history, risk perception and RRM intention. Multivariate logistic regression was used to analyze the relation between psychological factors and women's intention to choose for RRM.RESULTS: Factors associated with RRM intention were high positive affect (OR = 1.86, 95%CI = 1.12-3.08), high negative affect (OR = 2.52, 95%CI = 1.44-4.43), high cancer worry (OR = 1.65, 95%CI = 1.00-2.72), high perceived personal control (OR = 3.58, 95%CI = 2.18-5.89), high risk-perception (OR = 1.85, 95%CI = 1.15-2.95) and having children (OR = 2.06, 95%CI = 1.21-3.50).CONCLUSION: Negative and positive affects play an important role in the intention for RRM. Furthermore, perceived personal control over the situation is associated with an intention for RRM. In addition to focusing on accurate risk communication, counseling should pay attention to the influence of perceived control and emotions to facilitate decision-making.

U2 - 10.1016/j.breast.2016.08.016

DO - 10.1016/j.breast.2016.08.016

M3 - Article

SN - 0960-9776

VL - 30

SP - 66

EP - 72

JO - Breast

JF - Breast

ER -

Psychological factors associated with the intention to choose for risk-reducing mastectomy in family cancer clinic attendees

Abstract

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