Protein kinase D: A family affair

An Rykx; Line de Kimpe; Svetlana Mikhalap; Tibor Vantus; Thomas Seufferlein; Jackie R. Vandenheede; Johan van Lint

doi:10.1016/S0014-5793(03)00487-3

Protein kinase D: A family affair

An Rykx
, Line de Kimpe
, Svetlana Mikhalap
, Tibor Vantus
, Thomas Seufferlein
, Jackie R. Vandenheede
, Johan van Lint

KU Leuven
Semmelweis University
Ulm University

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

The protein kinase D family of enzymes consists of three isoforms: PKD1/PKCμ, PKD2 and PKD3/PKCν. They all share a similar architecture with regulatory sub-domains that play specific roles in the activation, translocation and function of the enzymes. The PKD enzymes have recently been implicated in very diverse cellular functions, including Golgi organization and plasma membrane directed transport, metastasis, immune responses, apoptosis and cell proliferation. © 2003 Published by Elsevier Science B.V. on behalf of the Federation of European Biochemical Societies.

Original language	English
Pages (from-to)	81-86
Journal	FEBS letters
Volume	546
Issue number	1
DOIs	https://doi.org/10.1016/S0014-5793(03)00487-3
Publication status	Published - 3 Jul 2003
Externally published	Yes

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

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10.1016/S0014-5793(03)00487-3

Cite this

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title = "Protein kinase D: A family affair",

abstract = "The protein kinase D family of enzymes consists of three isoforms: PKD1/PKCμ, PKD2 and PKD3/PKCν. They all share a similar architecture with regulatory sub-domains that play specific roles in the activation, translocation and function of the enzymes. The PKD enzymes have recently been implicated in very diverse cellular functions, including Golgi organization and plasma membrane directed transport, metastasis, immune responses, apoptosis and cell proliferation. {\textcopyright} 2003 Published by Elsevier Science B.V. on behalf of the Federation of European Biochemical Societies.",

author = "An Rykx and \{de Kimpe\}, Line and Svetlana Mikhalap and Tibor Vantus and Thomas Seufferlein and Vandenheede, \{Jackie R.\} and \{van Lint\}, Johan",

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doi = "10.1016/S0014-5793(03)00487-3",

language = "English",

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T2 - A family affair

AU - Rykx, An

AU - de Kimpe, Line

AU - Mikhalap, Svetlana

AU - Vantus, Tibor

AU - Seufferlein, Thomas

AU - Vandenheede, Jackie R.

AU - van Lint, Johan

PY - 2003/7/3

Y1 - 2003/7/3

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AB - The protein kinase D family of enzymes consists of three isoforms: PKD1/PKCμ, PKD2 and PKD3/PKCν. They all share a similar architecture with regulatory sub-domains that play specific roles in the activation, translocation and function of the enzymes. The PKD enzymes have recently been implicated in very diverse cellular functions, including Golgi organization and plasma membrane directed transport, metastasis, immune responses, apoptosis and cell proliferation. © 2003 Published by Elsevier Science B.V. on behalf of the Federation of European Biochemical Societies.

UR - https://www.scopus.com/pages/publications/0037524470

UR - https://www.ncbi.nlm.nih.gov/pubmed/12829240

U2 - 10.1016/S0014-5793(03)00487-3

DO - 10.1016/S0014-5793(03)00487-3

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SN - 0014-5793

VL - 546

SP - 81

EP - 86

JO - FEBS letters

JF - FEBS letters

IS - 1

ER -

Protein kinase D: A family affair

Abstract

UN SDGs

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