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Probability of major depression classification based on the SCID, CIDI, and MINI diagnostic interviews: A synthesis of three individual participant data meta-analyses

  • DEPRESsion Screening Data (DEPRESSD) Collaboration
  • McGill University
  • Douglas Mental Health University Institute, Department of Psychiatry, McGill University, Montreal, Canada
  • Keele University
  • Stanford University
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  • VU University Medical Hospital
  • University of York
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  • Johns Hopkins University School of Medicine
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  • Laboratorio de Investigación Biomédica, Facultad de Medicina y Nutrición, Avenida Universidad, Dgo, Mexico
  • University of Washington
  • The University of Auckland
  • Bar-Ilan University
  • Child and Adolescent Unit, Federal Neuropsychiatric Hospital, Enugu, Nigeria
  • Iran University of Medical Sciences
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  • Department of Psychiatry, Rajarajeswari Medical College and Hospital, Bengaluru, Karnataka, India
  • University of Connecticut
  • Technical University of Munich
  • University of Manitoba
  • University of KwaZulu-Natal
  • University of Hamburg
  • Sydney Medical School
  • University Hospital Zürich
  • Department of Psychiatry, Hospital Mesra Bukit Padang, Sabah, Malaysia
  • Lithuanian University of Health Sciences
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  • University of Newcastle
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  • University of the Witwatersrand
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  • Department of Psychiatry. Institut de Neuropsiquiatria i Addiccions, Centre Emili Mira, Parc de Salut Mar. Barcelona. Spain
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  • National Center of Neurology and Psychiatry Kodaira
  • Yale University

Research output: Contribution to journalArticleAcademicpeer-review

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Abstract

Introduction: Three previous individual participant data meta-analyses (IPDMAs) reported that, compared to the Structured Clinical Interview for the DSM (SCID), alternative reference standards, primarily the Composite International Diagnostic Interview (CIDI) and the Mini International Neuropsychiatric Interview (MINI), tended to misclassify major depression status, when controlling for depression symptom severity. However, there was an important lack of precision in the results. Objective: To compare the odds of the major depression classification based on the SCID, CIDI, and MINI. Methods: We included and standardized data from 3 IPDMA databases. For each IPDMA, separately, we fitted binomial generalized linear mixed models to compare the adjusted odds ratios (aORs) of major depression classification, controlling for symptom severity and characteristics of participants, and the interaction between interview and symptom severity. Next, we synthesized results using a DerSimonian-Laird random-effects meta-analysis. Results: In total, 69,405 participants (7,574 [11%] with major depression) from 212 studies were included. Controlling for symptom severity and participant characteristics, the MINI (74 studies; 25,749 participants) classified major depression more often than the SCID (108 studies; 21,953 participants; aOR 1.46; 95% confidence interval [CI] 1.11-1.92]). Classification odds for the CIDI (30 studies; 21,703 participants) and the SCID did not differ overall (aOR 1.19; 95% CI 0.79-1.75); however, as screening scores increased, the aOR increased less for the CIDI than the SCID (interaction aOR 0.64; 95% CI 0.52-0.80). Conclusions: Compared to the SCID, the MINI classified major depression more often. The odds of the depression classification with the CIDI increased less as symptom levels increased. Interpretation of research that uses diagnostic interviews to classify depression should consider the interview characteristics.
Original languageEnglish
Pages (from-to)28-40
JournalPsychotherapy and psychosomatics
Volume90
Issue number1
DOIs
Publication statusPublished - 1 Dec 2020

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