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Predictors of coronavirus disease 19 (COVID-19) pneumonitis outcome based on computed tomography (CT) imaging obtained prior to hospitalization: a retrospective study

  • Mohammad Mirza-Aghazadeh-Attari
  • , Armin Zarrintan
  • , Nariman Nezami
  • , Afshin Mohammadi
  • , Anita Zarrintan
  • , Iraj Mohebbi
  • , Habibollah Pirnejad
  • , Kamal Khademvatani
  • , Zahra Ashkavand
  • , Payman Forughi
  • , Amin Arasteh
  • , Javad Aghazadeh Attari*
  • *Corresponding author for this work
  • Tabriz University of Medical Sciences
  • Urmia University of Medical Sciences
  • Johns Hopkins University
  • Albany Medical College

Research output: Contribution to journalArticleAcademicpeer-review

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Abstract

Purpose: Computed tomography (CT) has been utilized as a diagnostic modality in the coronavirus disease 19 (COVID-19), while some studies have also suggested a prognostic role for it. This study aimed to assess the diagnostic and prognostic value of computed tomography (CT) imaging in COVID-19 patients. Methods: This was a retrospective study of fifty patients with COVID-19 pneumonia. Twenty-seven patients survived, while 23 passed away. CT imaging was performed in all of the patients on the day of admission. Imaging findings were interpreted based on current guidelines by two expert radiologists. Imaging findings were compared between surviving and deceased patients. Lung scores were assigned to patients based on CT chest findings. Then, the receiver operating characteristic curve was used to determine cutoff values for lung scores. Results: The common radiologic findings were ground-glass opacities (82%) and airspace consolidation (42%), respectively. Air bronchogram was more commonly seen in deceased patients (p = 0.04). Bilateral and multilobar involvement was more frequently found in deceased patients (p = 0.049 and 0.014, respectively). The mean number of involved lobes was 3.46 ± 1.80 lobes in surviving patients and 4.57 ± 0.60 lobes in the deceased patients (p = 0.009). The difference was statistically significant. The area under the curve for a lung score cutoff of 12 was 0.790. Conclusion: Air bronchogram and bilateral and multilobar involvement were more frequently seen in deceased patients and may suggest a poor outcome for COVID-19 pneumonia.

Original languageEnglish
Pages (from-to)653-661
Number of pages9
JournalEmergency radiology
Volume27
Issue number6
DOIs
Publication statusPublished - Dec 2020

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

  1. SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well-being

Keywords

  • COVID-19
  • CT
  • Outcome
  • Pneumonia
  • Prognosis
  • SARS-Cov-2

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