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Potential of fibrates in the treatment of fatty acid oxidation disorders: revival of classical drugs?

  • F. Djouadi
  • , F. Aubey
  • , D. Schlemmer
  • , S. Gobin
  • , P. Laforet
  • , R. J. A. Wanders
  • , A. W. Strauss
  • , J. P. Bonnefont
  • , J. Bastin

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

Exposure to fibrates leads to normalization of fatty acid oxidation (FAO) in fibroblasts from patients with myopathic forms of CPT2 deficiency or VLCAD deficiency. Correction of FAO is related to a drug-induced increase of residual enzyme activity, and this could provide a new treatment strategy for these disorders
Original languageEnglish
Pages (from-to)341-342
JournalJournal of inherited metabolic disease
Volume29
Issue number2-3
DOIs
Publication statusPublished - 2006

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

  1. SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well-being

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