Panlobar nephroblastomatosis: a distinctive form of renal dysplasia associated with Wilms' tumour

N. WALFORD

doi:10.1111/j.1365-2559.1990.tb00661.x

Panlobar nephroblastomatosis: a distinctive form of renal dysplasia associated with Wilms' tumour

N. WALFORD^*

^*Corresponding author for this work

University of Amsterdam

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

An increasing variety of dysplastic lesions of metanephric origin (‘the nephroblastomatosis complex’) have been recognized as precursors of Wilms' tumour. We describe here four cases of a hitherto unrecognized renal dysplasia associated with Wilms' tumour and having a panlobar distribution. It has many features in common with the intralobar form of nephroblastomatosis, but differs in extending through the full thickness of the renal substance from calyx to capsule. These cases are also characterized by an increased proportion of well‐differentiated tissue elements and by the presence, in some cases, of anomalous metanephric differentiation in the pericalyceal tissues or renal capsule. Copyright © 1990, Wiley Blackwell. All rights reserved

Original language	English
Pages (from-to)	37-44
Journal	Histopathology
Volume	17
Issue number	1
DOIs	https://doi.org/10.1111/j.1365-2559.1990.tb00661.x
Publication status	Published - 1990
Externally published	Yes

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title = "Panlobar nephroblastomatosis: a distinctive form of renal dysplasia associated with Wilms' tumour",

abstract = "An increasing variety of dysplastic lesions of metanephric origin ({\textquoteleft}the nephroblastomatosis complex{\textquoteright}) have been recognized as precursors of Wilms' tumour. We describe here four cases of a hitherto unrecognized renal dysplasia associated with Wilms' tumour and having a panlobar distribution. It has many features in common with the intralobar form of nephroblastomatosis, but differs in extending through the full thickness of the renal substance from calyx to capsule. These cases are also characterized by an increased proportion of well‐differentiated tissue elements and by the presence, in some cases, of anomalous metanephric differentiation in the pericalyceal tissues or renal capsule. Copyright {\textcopyright} 1990, Wiley Blackwell. All rights reserved",

author = "N. WALFORD",

year = "1990",

doi = "10.1111/j.1365-2559.1990.tb00661.x",

language = "English",

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pages = "37--44",

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N2 - An increasing variety of dysplastic lesions of metanephric origin (‘the nephroblastomatosis complex’) have been recognized as precursors of Wilms' tumour. We describe here four cases of a hitherto unrecognized renal dysplasia associated with Wilms' tumour and having a panlobar distribution. It has many features in common with the intralobar form of nephroblastomatosis, but differs in extending through the full thickness of the renal substance from calyx to capsule. These cases are also characterized by an increased proportion of well‐differentiated tissue elements and by the presence, in some cases, of anomalous metanephric differentiation in the pericalyceal tissues or renal capsule. Copyright © 1990, Wiley Blackwell. All rights reserved

AB - An increasing variety of dysplastic lesions of metanephric origin (‘the nephroblastomatosis complex’) have been recognized as precursors of Wilms' tumour. We describe here four cases of a hitherto unrecognized renal dysplasia associated with Wilms' tumour and having a panlobar distribution. It has many features in common with the intralobar form of nephroblastomatosis, but differs in extending through the full thickness of the renal substance from calyx to capsule. These cases are also characterized by an increased proportion of well‐differentiated tissue elements and by the presence, in some cases, of anomalous metanephric differentiation in the pericalyceal tissues or renal capsule. Copyright © 1990, Wiley Blackwell. All rights reserved

UR - https://www.scopus.com/pages/publications/0025290748

UR - https://www.ncbi.nlm.nih.gov/pubmed/2172141

U2 - 10.1111/j.1365-2559.1990.tb00661.x

DO - 10.1111/j.1365-2559.1990.tb00661.x

M3 - Article

C2 - 2172141

SN - 0309-0167

VL - 17

SP - 37

EP - 44

JO - Histopathology

JF - Histopathology

IS - 1

ER -

Panlobar nephroblastomatosis: a distinctive form of renal dysplasia associated with Wilms' tumour

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