Abstract
Introduction
Up to 70% of people with Multiple Sclerosis (MS) become unemployed within ten years after diagnosis. The effectiveness of vocational rehabilitation for people with MS is limited and few new trials have been published in the past decade. Studies examining the effectiveness of interventions to tackle MS-related problems are increasingly including work outcomes. We aim to review the effectiveness of these interventions on work participation in MS.
Methods
We will search Cochrane Central Register of Controlled Trials, MEDLINE, EMBASE, PsychINFO, OTseeker and Web of Science. Additionally, we will hand-search unpublished trials and relevant unindexed journals. We will include randomized controlled trials and before-after studies comparing the effects of non-pharmacological interventions, specifically vocational, psychological and exercise interventions, on work participation with alternative interventions or care as usual in people with MS. Risk of bias will be assessed using the RoB2 Excel tool. Finally, we will pool data from studies we judge to be clinically homogeneous using RevMan Web. If more than one study provide usable data in any single comparison, we will perform meta-analysis.
Results
This title has been accepted by Cochrane and we are currently in the process of finalizing our protocol for publication. The review will be conducted and written in the second half of 2023 and will be published in the first half of 2024. The results will be presented at ICOH 2024.
Discussion and Conclusion
This review aims to determine whether non-pharmacological interventions offered to people with MS are more effective in changing work outcomes compared to alternative interventions or care as usual.
Up to 70% of people with Multiple Sclerosis (MS) become unemployed within ten years after diagnosis. The effectiveness of vocational rehabilitation for people with MS is limited and few new trials have been published in the past decade. Studies examining the effectiveness of interventions to tackle MS-related problems are increasingly including work outcomes. We aim to review the effectiveness of these interventions on work participation in MS.
Methods
We will search Cochrane Central Register of Controlled Trials, MEDLINE, EMBASE, PsychINFO, OTseeker and Web of Science. Additionally, we will hand-search unpublished trials and relevant unindexed journals. We will include randomized controlled trials and before-after studies comparing the effects of non-pharmacological interventions, specifically vocational, psychological and exercise interventions, on work participation with alternative interventions or care as usual in people with MS. Risk of bias will be assessed using the RoB2 Excel tool. Finally, we will pool data from studies we judge to be clinically homogeneous using RevMan Web. If more than one study provide usable data in any single comparison, we will perform meta-analysis.
Results
This title has been accepted by Cochrane and we are currently in the process of finalizing our protocol for publication. The review will be conducted and written in the second half of 2023 and will be published in the first half of 2024. The results will be presented at ICOH 2024.
Discussion and Conclusion
This review aims to determine whether non-pharmacological interventions offered to people with MS are more effective in changing work outcomes compared to alternative interventions or care as usual.
| Original language | English |
|---|---|
| Pages (from-to) | 0 |
| Number of pages | 1 |
| Journal | Occupational Medicine |
| Volume | 74 |
| Issue number | Supplement_1 |
| DOIs | |
| Publication status | Published - 3 Jul 2024 |