Orthostatic hypotension due to suppression of vasomotor outflow after amphetamine intoxication

A. A. Smit; W. Wieling; A. J. Voogel; R. W. Koster; P. A. van Zwieten

doi:10.4065/71.11.1067

Orthostatic hypotension due to suppression of vasomotor outflow after amphetamine intoxication

A. A. Smit
, W. Wieling
, A. J. Voogel
, R. W. Koster
, P. A. van Zwieten

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

Ten hours after ingestion of amphetamines, a previously healthy 17-year-old female adolescent experienced dizziness on standing. Examination revealed pronounced drowsiness and severe orthostatic hypotension. Assessment of arterial baroreflex function suggested that suppressed sympathetic vasomotor drive was the cause of the orthostatic hypotension. Within 3 days, the baroreflex failure resolved spontaneously. To our knowledge, suppressed vasomotor outflow after ingestion of amphetamines has been previously observed only in animal studies

Original language	English
Pages (from-to)	1067-1070
Journal	Mayo Clinic proceedings. Mayo Clinic
Volume	71
Issue number	11
DOIs	https://doi.org/10.4065/71.11.1067
Publication status	Published - 1996

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title = "Orthostatic hypotension due to suppression of vasomotor outflow after amphetamine intoxication",

abstract = "Ten hours after ingestion of amphetamines, a previously healthy 17-year-old female adolescent experienced dizziness on standing. Examination revealed pronounced drowsiness and severe orthostatic hypotension. Assessment of arterial baroreflex function suggested that suppressed sympathetic vasomotor drive was the cause of the orthostatic hypotension. Within 3 days, the baroreflex failure resolved spontaneously. To our knowledge, suppressed vasomotor outflow after ingestion of amphetamines has been previously observed only in animal studies",

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AU - Wieling, W.

AU - Voogel, A. J.

AU - Koster, R. W.

AU - van Zwieten, P. A.

PY - 1996

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AB - Ten hours after ingestion of amphetamines, a previously healthy 17-year-old female adolescent experienced dizziness on standing. Examination revealed pronounced drowsiness and severe orthostatic hypotension. Assessment of arterial baroreflex function suggested that suppressed sympathetic vasomotor drive was the cause of the orthostatic hypotension. Within 3 days, the baroreflex failure resolved spontaneously. To our knowledge, suppressed vasomotor outflow after ingestion of amphetamines has been previously observed only in animal studies

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DO - 10.4065/71.11.1067

M3 - Article

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SN - 0025-6196

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SP - 1067

EP - 1070

JO - Mayo Clinic proceedings. Mayo Clinic

JF - Mayo Clinic proceedings. Mayo Clinic

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ER -

Orthostatic hypotension due to suppression of vasomotor outflow after amphetamine intoxication

Abstract

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