Ongoing pregnancy qualifies best as the primary outcome measure of choice in trials in reproductive medicine: an opinion paper: an opinion paper

Miriam Braakhekke; Esme I. Kamphuis; Eline A. Dancet; Femke Mol; Fulco van der Veen; Ben W. Mol

doi:10.1016/j.fertnstert.2014.03.047

Ongoing pregnancy qualifies best as the primary outcome measure of choice in trials in reproductive medicine: an opinion paper: an opinion paper

Miriam Braakhekke
, Esme I. Kamphuis
, Eline A. Dancet
, Femke Mol
, Fulco van der Veen
, Ben W. Mol

Research output: Contribution to journal › Review article › Academic › peer-review

Abstract

The most appropriate primary outcome measure for reproductive medicine has been discussed frequently. In 2003 the European Society for Human Reproduction and Embryology recommended that the outcome measure of assisted reproductive technology (ART) and non-ART should be singleton live birth. Although live birth is indeed the aim of clinical practice, and there is no discussion that it should be reported in infertility trials, we hereby provide arguments that plead for using ongoing pregnancy as the primary outcome in such trials. We feel that ongoing pregnancy best serves the many purposes of a primary outcome and best reflects the effectiveness of a treatment

Original language	English
Pages (from-to)	1203-1204
Number of pages	2
Journal	Fertility and sterility
Volume	101
Issue number	5
DOIs	https://doi.org/10.1016/j.fertnstert.2014.03.047
Publication status	Published - 2014

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Choice Behavior
Clinical Trials as Topic/standards
Female
Humans
Live Birth/epidemiology
Pregnancy
Pregnancy Rate
Reproductive Medicine/standards
Reproductive Techniques, Assisted/standards
Treatment Outcome

Access to Document

10.1016/j.fertnstert.2014.03.047

Cite this

@article{e45ded8cea464be3be3185577a59fe07,

title = "Ongoing pregnancy qualifies best as the primary outcome measure of choice in trials in reproductive medicine: an opinion paper: an opinion paper",

abstract = "The most appropriate primary outcome measure for reproductive medicine has been discussed frequently. In 2003 the European Society for Human Reproduction and Embryology recommended that the outcome measure of assisted reproductive technology (ART) and non-ART should be singleton live birth. Although live birth is indeed the aim of clinical practice, and there is no discussion that it should be reported in infertility trials, we hereby provide arguments that plead for using ongoing pregnancy as the primary outcome in such trials. We feel that ongoing pregnancy best serves the many purposes of a primary outcome and best reflects the effectiveness of a treatment",

keywords = "Choice Behavior, Clinical Trials as Topic/standards, Female, Humans, Live Birth/epidemiology, Pregnancy, Pregnancy Rate, Reproductive Medicine/standards, Reproductive Techniques, Assisted/standards, Treatment Outcome",

author = "Miriam Braakhekke and Kamphuis, \{Esme I.\} and Dancet, \{Eline A.\} and Femke Mol and \{van der Veen\}, Fulco and Mol, \{Ben W.\}",

year = "2014",

doi = "10.1016/j.fertnstert.2014.03.047",

language = "English",

volume = "101",

pages = "1203--1204",

journal = "Fertility and sterility",

issn = "0015-0282",

publisher = "Elsevier Inc.",

number = "5",

}

TY - JOUR

T1 - Ongoing pregnancy qualifies best as the primary outcome measure of choice in trials in reproductive medicine: an opinion paper

T2 - an opinion paper

AU - Braakhekke, Miriam

AU - Kamphuis, Esme I.

AU - Dancet, Eline A.

AU - Mol, Femke

AU - van der Veen, Fulco

AU - Mol, Ben W.

PY - 2014

Y1 - 2014

N2 - The most appropriate primary outcome measure for reproductive medicine has been discussed frequently. In 2003 the European Society for Human Reproduction and Embryology recommended that the outcome measure of assisted reproductive technology (ART) and non-ART should be singleton live birth. Although live birth is indeed the aim of clinical practice, and there is no discussion that it should be reported in infertility trials, we hereby provide arguments that plead for using ongoing pregnancy as the primary outcome in such trials. We feel that ongoing pregnancy best serves the many purposes of a primary outcome and best reflects the effectiveness of a treatment

AB - The most appropriate primary outcome measure for reproductive medicine has been discussed frequently. In 2003 the European Society for Human Reproduction and Embryology recommended that the outcome measure of assisted reproductive technology (ART) and non-ART should be singleton live birth. Although live birth is indeed the aim of clinical practice, and there is no discussion that it should be reported in infertility trials, we hereby provide arguments that plead for using ongoing pregnancy as the primary outcome in such trials. We feel that ongoing pregnancy best serves the many purposes of a primary outcome and best reflects the effectiveness of a treatment

KW - Choice Behavior

KW - Clinical Trials as Topic/standards

KW - Female

KW - Humans

KW - Live Birth/epidemiology

KW - Pregnancy

KW - Pregnancy Rate

KW - Reproductive Medicine/standards

KW - Reproductive Techniques, Assisted/standards

KW - Treatment Outcome

U2 - 10.1016/j.fertnstert.2014.03.047

DO - 10.1016/j.fertnstert.2014.03.047

M3 - Review article

C2 - 24786739

SN - 0015-0282

VL - 101

SP - 1203

EP - 1204

JO - Fertility and sterility

JF - Fertility and sterility

IS - 5

ER -

Ongoing pregnancy qualifies best as the primary outcome measure of choice in trials in reproductive medicine: an opinion paper: an opinion paper

Abstract

UN SDGs

Keywords

Access to Document

Fingerprint

Cite this