Non-immune hydrops fetalis: A short review of etiology and pathophysiology

Carlo Bellini; Raoul C. M. Hennekam

doi:10.1002/ajmg.a.34438

Non-immune hydrops fetalis: A short review of etiology and pathophysiology

Carlo Bellini
, Raoul C. M. Hennekam

Research output: Contribution to journal › Review article › Academic › peer-review

Abstract

Hydrops fetalis is an excessive accumulation of fetal fluid. Hydrops is traditionally classified into either immune or non-immune hydrops (NIHF), but in practice, nowadays in the Western world >90% of hydrops is of non-immune origin. The basis of the disorder is an imbalance in the regulation of fetal fluid movement between the vascular and interstitial space. We previously suggested a diagnostic flow-chart for NIHF. In this short review we describe the main mechanisms leading to NIHF. (c) 2012 Wiley Periodicals, Inc

Original language	English
Pages (from-to)	597-605
Journal	American journal of medical genetics. Part A
Volume	158A
Issue number	3
DOIs	https://doi.org/10.1002/ajmg.a.34438
Publication status	Published - 2012

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10.1002/ajmg.a.34438

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abstract = "Hydrops fetalis is an excessive accumulation of fetal fluid. Hydrops is traditionally classified into either immune or non-immune hydrops (NIHF), but in practice, nowadays in the Western world >90\% of hydrops is of non-immune origin. The basis of the disorder is an imbalance in the regulation of fetal fluid movement between the vascular and interstitial space. We previously suggested a diagnostic flow-chart for NIHF. In this short review we describe the main mechanisms leading to NIHF. (c) 2012 Wiley Periodicals, Inc",

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AB - Hydrops fetalis is an excessive accumulation of fetal fluid. Hydrops is traditionally classified into either immune or non-immune hydrops (NIHF), but in practice, nowadays in the Western world >90% of hydrops is of non-immune origin. The basis of the disorder is an imbalance in the regulation of fetal fluid movement between the vascular and interstitial space. We previously suggested a diagnostic flow-chart for NIHF. In this short review we describe the main mechanisms leading to NIHF. (c) 2012 Wiley Periodicals, Inc

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Non-immune hydrops fetalis: A short review of etiology and pathophysiology

Abstract

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