Non-atheromatous arterial stenoses in atypical haemolytic uraemic syndrome associated with complement dysregulation

Chantal Loirat; Marie-Alice Macher; Monique Elmaleh-Berges; Theresa Kwon; Georges Deschênes; Timothy H. J. Goodship; Charles Majoie; Jean-Claude Davin; Raphael Blanc; Julien Savatovsky; Jacques Moret; Véronique Fremeaux-Bacchi

doi:10.1093/ndt/gfq319

Non-atheromatous arterial stenoses in atypical haemolytic uraemic syndrome associated with complement dysregulation

Chantal Loirat
, Marie-Alice Macher
, Monique Elmaleh-Berges
, Theresa Kwon
, Georges Deschênes
, Timothy H. J. Goodship
, Charles Majoie
, Jean-Claude Davin
, Raphael Blanc
, Julien Savatovsky
, Jacques Moret
, Véronique Fremeaux-Bacchi

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

Results. Stenoses of both carotid arteries, left subclavian and vertebral arteries, several intracranial, right humeral, several coronary, and all pulmonary arteries were demonstrated. At the age of 13 years, left subclavian and right cervical carotid arteries were occluded. Right carotid recanalization induced intracranial dissection and death. The child had a Lys350Asp factor B mutation. Conclusion. Arterial steno-occlusive lesions appear as potential complications of dysregulated complement activation in aHUS. Endovascular treatment should be considered cautiously in this setting

Original language	English
Pages (from-to)	3421-3425
Journal	Nephrology, dialysis, transplantation
Volume	25
Issue number	10
DOIs	https://doi.org/10.1093/ndt/gfq319
Publication status	Published - 2010

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SDG 3 Good Health and Well-being

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10.1093/ndt/gfq319

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Loirat, C., Macher, M.-A., Elmaleh-Berges, M., Kwon, T., Deschênes, G., Goodship, T. H. J., Majoie, C., Davin, J.-C., Blanc, R., Savatovsky, J., Moret, J., & Fremeaux-Bacchi, V. (2010). Non-atheromatous arterial stenoses in atypical haemolytic uraemic syndrome associated with complement dysregulation. Nephrology, dialysis, transplantation, 25(10), 3421-3425. https://doi.org/10.1093/ndt/gfq319

@article{beca5adf51654c1d9812146cdb456a01,

title = "Non-atheromatous arterial stenoses in atypical haemolytic uraemic syndrome associated with complement dysregulation",

abstract = "Results. Stenoses of both carotid arteries, left subclavian and vertebral arteries, several intracranial, right humeral, several coronary, and all pulmonary arteries were demonstrated. At the age of 13 years, left subclavian and right cervical carotid arteries were occluded. Right carotid recanalization induced intracranial dissection and death. The child had a Lys350Asp factor B mutation. Conclusion. Arterial steno-occlusive lesions appear as potential complications of dysregulated complement activation in aHUS. Endovascular treatment should be considered cautiously in this setting",

author = "Chantal Loirat and Marie-Alice Macher and Monique Elmaleh-Berges and Theresa Kwon and Georges Desch{\^e}nes and Goodship, \{Timothy H. J.\} and Charles Majoie and Jean-Claude Davin and Raphael Blanc and Julien Savatovsky and Jacques Moret and V{\'e}ronique Fremeaux-Bacchi",

year = "2010",

doi = "10.1093/ndt/gfq319",

language = "English",

volume = "25",

pages = "3421--3425",

journal = "Nephrology, dialysis, transplantation",

issn = "0931-0509",

publisher = "Oxford University Press",

number = "10",

}

Loirat, C, Macher, M-A, Elmaleh-Berges, M, Kwon, T, Deschênes, G, Goodship, THJ, Majoie, C, Davin, J-C, Blanc, R, Savatovsky, J, Moret, J & Fremeaux-Bacchi, V 2010, 'Non-atheromatous arterial stenoses in atypical haemolytic uraemic syndrome associated with complement dysregulation', Nephrology, dialysis, transplantation, vol. 25, no. 10, pp. 3421-3425. https://doi.org/10.1093/ndt/gfq319

TY - JOUR

T1 - Non-atheromatous arterial stenoses in atypical haemolytic uraemic syndrome associated with complement dysregulation

AU - Loirat, Chantal

AU - Macher, Marie-Alice

AU - Elmaleh-Berges, Monique

AU - Kwon, Theresa

AU - Deschênes, Georges

AU - Goodship, Timothy H. J.

AU - Majoie, Charles

AU - Davin, Jean-Claude

AU - Blanc, Raphael

AU - Savatovsky, Julien

AU - Moret, Jacques

AU - Fremeaux-Bacchi, Véronique

PY - 2010

Y1 - 2010

N2 - Results. Stenoses of both carotid arteries, left subclavian and vertebral arteries, several intracranial, right humeral, several coronary, and all pulmonary arteries were demonstrated. At the age of 13 years, left subclavian and right cervical carotid arteries were occluded. Right carotid recanalization induced intracranial dissection and death. The child had a Lys350Asp factor B mutation. Conclusion. Arterial steno-occlusive lesions appear as potential complications of dysregulated complement activation in aHUS. Endovascular treatment should be considered cautiously in this setting

AB - Results. Stenoses of both carotid arteries, left subclavian and vertebral arteries, several intracranial, right humeral, several coronary, and all pulmonary arteries were demonstrated. At the age of 13 years, left subclavian and right cervical carotid arteries were occluded. Right carotid recanalization induced intracranial dissection and death. The child had a Lys350Asp factor B mutation. Conclusion. Arterial steno-occlusive lesions appear as potential complications of dysregulated complement activation in aHUS. Endovascular treatment should be considered cautiously in this setting

U2 - 10.1093/ndt/gfq319

DO - 10.1093/ndt/gfq319

M3 - Article

C2 - 20530807

SN - 0931-0509

VL - 25

SP - 3421

EP - 3425

JO - Nephrology, dialysis, transplantation

JF - Nephrology, dialysis, transplantation

IS - 10

ER -

Non-atheromatous arterial stenoses in atypical haemolytic uraemic syndrome associated with complement dysregulation

Abstract

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