Neuromodulation in obsessive-compulsive disorder

Melisse Bais; Martijn Figee; Damiaan Denys

doi:10.1016/j.psc.2014.06.003

Neuromodulation in obsessive-compulsive disorder

Melisse Bais
, Martijn Figee
, Damiaan Denys

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

Neuromodulation techniques in obsessive-compulsive disorder (OCD) involve electroconvulsive therapy (ECT), transcranial direct current stimulation (tDCS), transcranial magnetic stimulation (TMS), and deep brain stimulation (DBS). This article reviews the available literature on the efficacy and applicability of these techniques in OCD. ECT is used for the treatment of comorbid depression or psychosis. One case report on tDCS showed no effects in OCD. Low-frequency TMS provides significant but mostly transient improvement of obsessive-compulsive symptoms. DBS shows a response rate of 60% in open and sham-controlled studies. In OCD, it can be concluded that DBS, although more invasive, is the most efficacious technique

Original language	English
Pages (from-to)	393-413
Journal	Psychiatric clinics of North America
Volume	37
Issue number	3
DOIs	https://doi.org/10.1016/j.psc.2014.06.003
Publication status	Published - 2014

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title = "Neuromodulation in obsessive-compulsive disorder",

abstract = "Neuromodulation techniques in obsessive-compulsive disorder (OCD) involve electroconvulsive therapy (ECT), transcranial direct current stimulation (tDCS), transcranial magnetic stimulation (TMS), and deep brain stimulation (DBS). This article reviews the available literature on the efficacy and applicability of these techniques in OCD. ECT is used for the treatment of comorbid depression or psychosis. One case report on tDCS showed no effects in OCD. Low-frequency TMS provides significant but mostly transient improvement of obsessive-compulsive symptoms. DBS shows a response rate of 60\% in open and sham-controlled studies. In OCD, it can be concluded that DBS, although more invasive, is the most efficacious technique",

author = "Melisse Bais and Martijn Figee and Damiaan Denys",

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doi = "10.1016/j.psc.2014.06.003",

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AU - Figee, Martijn

AU - Denys, Damiaan

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AB - Neuromodulation techniques in obsessive-compulsive disorder (OCD) involve electroconvulsive therapy (ECT), transcranial direct current stimulation (tDCS), transcranial magnetic stimulation (TMS), and deep brain stimulation (DBS). This article reviews the available literature on the efficacy and applicability of these techniques in OCD. ECT is used for the treatment of comorbid depression or psychosis. One case report on tDCS showed no effects in OCD. Low-frequency TMS provides significant but mostly transient improvement of obsessive-compulsive symptoms. DBS shows a response rate of 60% in open and sham-controlled studies. In OCD, it can be concluded that DBS, although more invasive, is the most efficacious technique

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DO - 10.1016/j.psc.2014.06.003

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EP - 413

JO - Psychiatric clinics of North America

JF - Psychiatric clinics of North America

IS - 3

ER -

Neuromodulation in obsessive-compulsive disorder

Abstract

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