Nephrogenic diabetes insipidus in children

Nine V.A.M. Knoers; Elena N. Levtchenko

doi:10.1007/978-3-662-43596-0_36

Nephrogenic diabetes insipidus in children

Nine V.A.M. Knoers^*
, Elena N. Levtchenko

^*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceeding › Chapter › Academic › peer-review

Abstract

Congenital nephrogenic diabetes insipidus (NDI) is a disorder associated with mutations in either the AVP2R or AQP2 gene, causing the inability of patients to concentrate their pro-urine, which leads to a high risk of dehydration. In this chapter, the clinical aspects as well as the current knowledge regarding the cell biological aspects of congenital X-linked, autosomal recessive and autosomal dominant NDI will be discussed, specifically addressing the latest developments within the field. Based on deepened mechanistic understanding, new therapeutic strategies are currently being explored, which we also describe here.

Original language	English
Title of host publication	Pediatric Nephrology, Seventh Edition
Publisher	Springer Berlin Heidelberg
Pages	1307-1327
Number of pages	21
ISBN (Electronic)	9783662435960
ISBN (Print)	9783662435953
DOIs	https://doi.org/10.1007/978-3-662-43596-0_36
Publication status	Published - 1 Jan 2015
Externally published	Yes

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

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10.1007/978-3-662-43596-0_36

Cite this

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Nephrogenic diabetes insipidus in children

Abstract

UN SDGs

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