Miltefosine Treatment of Leishmania major Infection: An Observational Study Involving Dutch Military Personnel Returning from Northern Afghanistan

P. P. A. M. van Thiel; T. Leenstra; P. A. Kager; H. J. de Vries; M. van Vugt; W. F. van der Meide; A. Bart; J. E. Zeegelaar; A. van der Sluis; H. D. F. H. Schallig; T. van Gool; W. R. Faber; P. J. de Vries

doi:10.1086/648726

Miltefosine Treatment of Leishmania major Infection: An Observational Study Involving Dutch Military Personnel Returning from Northern Afghanistan

P. P. A. M. van Thiel
, T. Leenstra
, P. A. Kager
, H. J. de Vries
, M. van Vugt
, W. F. van der Meide
, A. Bart
, J. E. Zeegelaar
, A. van der Sluis
, H. D. F. H. Schallig
, T. van Gool
, W. R. Faber
, P. J. de Vries

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

In a retrospective, observational study involving 34 patients with Leishmania major infection, 31 of whom had experienced unsuccessful treatment with intralesional antimony (ilSb(v)), miltefosine proved effective. Thirty patients experienced cure after receipt of miltefosine, 3 after receipt of additional ilSbv, and 1 after 28 daily intravenous injections of antimony. Temporary diminution of ejaculate volume was reported by 21 patients

Original language	English
Pages (from-to)	80-83
Journal	Clinical infectious diseases
Volume	50
Issue number	1
DOIs	https://doi.org/10.1086/648726
Publication status	Published - 2010

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10.1086/648726

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van Thiel, P. P. A. M., Leenstra, T., Kager, P. A., de Vries, H. J., van Vugt, M., van der Meide, W. F., Bart, A., Zeegelaar, J. E., van der Sluis, A., Schallig, H. D. F. H., van Gool, T., Faber, W. R., & de Vries, P. J. (2010). Miltefosine Treatment of Leishmania major Infection: An Observational Study Involving Dutch Military Personnel Returning from Northern Afghanistan. Clinical infectious diseases, 50(1), 80-83. https://doi.org/10.1086/648726

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title = "Miltefosine Treatment of Leishmania major Infection: An Observational Study Involving Dutch Military Personnel Returning from Northern Afghanistan",

abstract = "In a retrospective, observational study involving 34 patients with Leishmania major infection, 31 of whom had experienced unsuccessful treatment with intralesional antimony (ilSb(v)), miltefosine proved effective. Thirty patients experienced cure after receipt of miltefosine, 3 after receipt of additional ilSbv, and 1 after 28 daily intravenous injections of antimony. Temporary diminution of ejaculate volume was reported by 21 patients",

author = "\{van Thiel\}, \{P. P. A. M.\} and T. Leenstra and Kager, \{P. A.\} and \{de Vries\}, \{H. J.\} and \{van Vugt\}, M. and \{van der Meide\}, \{W. F.\} and A. Bart and Zeegelaar, \{J. E.\} and \{van der Sluis\}, A. and Schallig, \{H. D. F. H.\} and \{van Gool\}, T. and Faber, \{W. R.\} and \{de Vries\}, \{P. J.\}",

year = "2010",

doi = "10.1086/648726",

language = "English",

volume = "50",

pages = "80--83",

journal = "Clinical infectious diseases",

issn = "1058-4838",

publisher = "Oxford University Press",

number = "1",

}

van Thiel, PPAM, Leenstra, T, Kager, PA, de Vries, HJ , van Vugt, M, van der Meide, WF, Bart, A, Zeegelaar, JE, van der Sluis, A, Schallig, HDFH , van Gool, T, Faber, WR & de Vries, PJ 2010, 'Miltefosine Treatment of Leishmania major Infection: An Observational Study Involving Dutch Military Personnel Returning from Northern Afghanistan', Clinical infectious diseases, vol. 50, no. 1, pp. 80-83. https://doi.org/10.1086/648726

TY - JOUR

T1 - Miltefosine Treatment of Leishmania major Infection: An Observational Study Involving Dutch Military Personnel Returning from Northern Afghanistan

AU - van Thiel, P. P. A. M.

AU - Leenstra, T.

AU - Kager, P. A.

AU - de Vries, H. J.

AU - van Vugt, M.

AU - van der Meide, W. F.

AU - Bart, A.

AU - Zeegelaar, J. E.

AU - van der Sluis, A.

AU - Schallig, H. D. F. H.

AU - van Gool, T.

AU - Faber, W. R.

AU - de Vries, P. J.

PY - 2010

Y1 - 2010

N2 - In a retrospective, observational study involving 34 patients with Leishmania major infection, 31 of whom had experienced unsuccessful treatment with intralesional antimony (ilSb(v)), miltefosine proved effective. Thirty patients experienced cure after receipt of miltefosine, 3 after receipt of additional ilSbv, and 1 after 28 daily intravenous injections of antimony. Temporary diminution of ejaculate volume was reported by 21 patients

AB - In a retrospective, observational study involving 34 patients with Leishmania major infection, 31 of whom had experienced unsuccessful treatment with intralesional antimony (ilSb(v)), miltefosine proved effective. Thirty patients experienced cure after receipt of miltefosine, 3 after receipt of additional ilSbv, and 1 after 28 daily intravenous injections of antimony. Temporary diminution of ejaculate volume was reported by 21 patients

U2 - 10.1086/648726

DO - 10.1086/648726

M3 - Article

C2 - 19951107

SN - 1058-4838

VL - 50

SP - 80

EP - 83

JO - Clinical infectious diseases

JF - Clinical infectious diseases

IS - 1

ER -

Miltefosine Treatment of Leishmania major Infection: An Observational Study Involving Dutch Military Personnel Returning from Northern Afghanistan

Abstract

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