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Migraine and perimenopause

  • Khatera Ibrahimi
  • , Emile G M Couturier
  • , Antoinette MaassenVanDenBrink
  • Division of Vascular Medicine and Pharmacology, Department of Internal Medicine, Erasmus University Medical Center, P.O. Box 2040, 3000 CA Rotterdam, The Netherlands.
  • Division of Vascular Medicine and Pharmacology, Department of Internal Medicine, Erasmus University Medical Center, P.O. Box 2040, 3000 CA Rotterdam, The Netherlands. Electronic address: [email protected].

Research output: Contribution to journalReview articleAcademicpeer-review

Abstract

Perimenopause and migraine are closely linked. The hormonal instability during the perimenopausal period not only causes vasomotor symptoms and mood disturbances, but also increases migraine incidence. Women do report new onset migraine during this period, but the increased incidence is reported by women with menstrually related migraine (MRM). The hormonal fluctuations can be stabilized with hormone replacement therapy (HRT), while simultaneously improving the migraine in some patients. The increased stroke risk in women with migraine with aura (MA) should be taken into consideration when intending to treat perimenopausal women with migraine with HRT.

Original languageEnglish
Pages (from-to)277-80
Number of pages4
JournalMaturitas
Volume78
Issue number4
DOIs
Publication statusPublished - Aug 2014

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

  1. SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well-being

Keywords

  • Estrogen Replacement Therapy/adverse effects
  • Hormones/metabolism
  • Humans
  • Menstruation
  • Migraine Disorders/drug therapy
  • Perimenopause/metabolism
  • Stroke/etiology

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