Microenema of 8-methoxypsoralen in photochemotherapy of psoriasis

A. H. Siddiqui, L. Stolk, H. R. Korthals Altes-Levij van Vinninghe, A. Kammeijer, R. H. Cormane

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Abstract

Reasonably high plasma levels were obtained 1/2 h after 8-methoxypsoralen (8-MOP) administration by microenema. This method was used in photochemotherapy of psoriasis and reasonably good clinical results with no serious side effects were obtained. The advantages of this modality include noninvolvement of the upper gastrointestinal tract, high bioavailability of psoralen, peak levels at a predictable time, and rapid elimination of the drug
Original languageEnglish
Pages (from-to)219-223
JournalArchives of dermatological research
Volume273
Issue number3-4
DOIs
Publication statusPublished - 1982

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