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Macrophage-mediated gliadin degradation and concomitant IL-27 production drive IL-10- and IFN-γ 3-secreting Tr1-like-cell differentiation in a murine model for gluten tolerance

  • M. A. Van Leeuwen
  • , L. M.M. Costes
  • , L. A. Van Berkel
  • , Y. Simons-Oosterhuis
  • , M. F. Du Pré
  • , A. E. Kozijn
  • , H. C. Raatgeep
  • , D. J. Lindenbergh-Kortleve
  • , N. Van Rooijen
  • , F. Koning
  • , J. N. Samsom*
  • *Corresponding author for this work
  • Erasmus University Medical Center
  • University of Oslo
  • Leiden University Medical Center - LUMC
  • Erasmus Medical Center

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Immunology and Microbiology

Pharmacology, Toxicology and Pharmaceutical Science