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Lung cancer biomarker testing: Perspective from Europe

  • Erik Thunnissen*
  • , Birgit Weynand
  • , Dalma Udovicic-Gagula
  • , Luka Brcic
  • , Malgorzata Szolkowska
  • , Paul Hofman
  • , Silvana Smojver-Ježek
  • , Sisko Anttila
  • , Fiorella Calabrese
  • , Izidor Kern
  • , Birgit Skov
  • , Sven Perner
  • , Vibeke G. Dale
  • , Zivka Eri
  • , Alex Haragan
  • , Diana Leonte
  • , Lina Carvallo
  • , Spasenja Savic Prince
  • , Siobhan Nicholson
  • , Irene Sansano
  • Ales Ryska
*Corresponding author for this work
  • Pathology Department, Herestraat, Leuven, Belgium
  • University of Sarajevo
  • Medical University of Graz
  • National Institute of Tuberculosis and Lung Diseases
  • CHU de Nice
  • University of Zagreb School of Medicine
  • Helsinki University Hospital and University of Helsinki
  • University of Padua
  • University of Ljubljana
  • University of Copenhagen
  • University of Lübeck
  • Pathology, Research Center Borstel, Leibniz Lung Center, Borstel, Germany
  • Norwegian University of Science and Technology
  • Institute for pulmonary diseases of Vojvodina, Department for Pathology, put dr Goldmana 4, Sremska Kamenica, Serbia
  • The Royal Liverpool University Hospital
  • National Institute of Pneumology, Pathology Department, Bucharest, Romania
  • University of Coimbra
  • University Hospital Basel
  • St James's Hospital
  • Pathology Department, Passeig de la Vall d’Hebron 119-129, Barcelona, Spain
  • Charles University

Research output: Contribution to journalReview articleAcademicpeer-review

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Abstract

A questionnaire on biomarker testing previously used in central European countries was extended and distributed in Western and Central European countries to the pathologists participating at the Pulmonary Pathology Society meeting 26–28 June 2019 in Dubrovnik, Croatia. Each country was represented by one responder. For recent biomarkers the availability and reimbursement of diagnoses of molecular alterations in non-small cell lung carcinoma varies widely between different, also western European, countries. Reimbursement of such assessments varies widely between unavailability and payments by the health care system or even pharmaceutical companies. The support for testing from alternative sources, such as the pharmaceutical industry, is no doubt partly compensating for the lack of public health system support, but it is not a viable or long‐term solution. Ideally, a structured access to testing and reimbursement should be the aim in order to provide patients with appropriate therapeutic options. As biomarker enabled therapies deliver a 50% better probability of outcome success, improved and unbiased reimbursement remains a major challenge for the future.
Original languageEnglish
Pages (from-to)887-897
Number of pages11
JournalTranslational Lung Cancer Research
Volume9
Issue number3
DOIs
Publication statusPublished - 1 Jun 2020

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

  1. SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well-being

Keywords

  • Europe
  • Health care
  • Lung cancer
  • Predictive testing
  • Therapy

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