Abstract
Patients with peripheral arterial disease (PAD) are at increased risk for ESRD and cardiovascular events. The primary objective was to assess the association between ankle-brachial index (ABI) values and renal outcome. The secondary objective was to evaluate whether statins and angiotensin-converting enzyme inhibitors (ACEI) are associated with improved renal and cardiovascular outcome in patients with PAD. In a prospective observational cohort study of 1940 consecutive patients with PAD, ABI was measured and chronic statin and ACEI therapy was noted at baseline. Serial creatinine concentrations were obtained at baseline, 6 mo, and every year after enrollment. End points were ESRD, all-cause mortality, and cardiac events during a median follow-up period of 8 yr. Baseline estimated GFR
| Original language | English |
|---|---|
| Pages (from-to) | 1872-1879 |
| Number of pages | 8 |
| Journal | Journal of the American Society of Nephrology |
| Volume | 18 |
| Issue number | 6 |
| DOIs | |
| Publication status | Published - 2007 |
UN SDGs
This output contributes to the following UN Sustainable Development Goals (SDGs)
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SDG 3 Good Health and Well-being
Keywords
- Aged
- Female
- Humans
- Male
- Middle Aged
- Risk Factors
- Prospective Studies
- Kaplan-Meier Estimate
- Multivariate Analysis
- Follow-Up Studies
- Angiotensin-Converting Enzyme Inhibitors/*therapeutic use
- Disease Progression
- Hydroxymethylglutaryl-CoA Reductase Inhibitors/*therapeutic use
- Kidney Failure, Chronic/*mortality/physiopathology
- Peripheral Vascular Diseases/*drug therapy/*mortality
- Prevalence
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Dive into the research topics of 'Lower progression rate of end-stage renal disease in patients with peripheral arterial disease using statins or Angiotensin-converting enzyme inhibitors. Journal of the American Society of Nephrology : JASN'. Together they form a unique fingerprint.Projects
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Risk management of complex surgical patients
Noordzij, P. (Principal investigator)
20/10/2010 → …
Project: Research
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