LOCALIZATION OF HUMAN PAPILLOMAVIRUS TYPE-16 DNA USING THE POLYMERASE CHAIN-REACTION IN THE CERVIX UTERI OF WOMEN WITH CERVICAL INTRAEPITHELIAL NEOPLASIA

M. T. Cornelissen; J. G. van den Tweel; A. P. Struyk; M. F. Jebbink; M. Briët; J. van der Noordaa; J. T. ter Schegget

doi:10.1099/0022-1317-70-10-2555

LOCALIZATION OF HUMAN PAPILLOMAVIRUS TYPE-16 DNA USING THE POLYMERASE CHAIN-REACTION IN THE CERVIX UTERI OF WOMEN WITH CERVICAL INTRAEPITHELIAL NEOPLASIA

M. T. Cornelissen
, J. G. van den Tweel
, A. P. Struyk
, M. F. Jebbink
, M. Briët
, J. van der Noordaa
, J. T. ter Schegget

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

The localization of human papillomavirus type 16 (HPV-16) DNA throughout the cervix uteri of women with cervical intraepithelial neoplasia (CIN) was studied by utilizing the polymerase chain reaction technique directly on histologically defined sections of paraffin-embedded cervical tissue obtained by conizations. HPV-16 DNA was detected only in the sections that contained CIN lesions and/or koilocytes. No HPV-16 DNA was detected in sections that contained only normal epithelium. This is in accordance with HPV-16 playing a role in the development of CIN lesions

Original language	English
Pages (from-to)	2555-2562
Journal	Journal of general virology
Volume	70
Issue number	10
DOIs	https://doi.org/10.1099/0022-1317-70-10-2555
Publication status	Published - 1989

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Cornelissen, M. T., van den Tweel, J. G., Struyk, A. P., Jebbink, M. F., Briët, M., van der Noordaa, J., & ter Schegget, J. T. (1989). LOCALIZATION OF HUMAN PAPILLOMAVIRUS TYPE-16 DNA USING THE POLYMERASE CHAIN-REACTION IN THE CERVIX UTERI OF WOMEN WITH CERVICAL INTRAEPITHELIAL NEOPLASIA. Journal of general virology, 70(10), 2555-2562. https://doi.org/10.1099/0022-1317-70-10-2555

@article{c6d2c01971d74deaa89cba8d4000b78c,

title = "LOCALIZATION OF HUMAN PAPILLOMAVIRUS TYPE-16 DNA USING THE POLYMERASE CHAIN-REACTION IN THE CERVIX UTERI OF WOMEN WITH CERVICAL INTRAEPITHELIAL NEOPLASIA",

abstract = "The localization of human papillomavirus type 16 (HPV-16) DNA throughout the cervix uteri of women with cervical intraepithelial neoplasia (CIN) was studied by utilizing the polymerase chain reaction technique directly on histologically defined sections of paraffin-embedded cervical tissue obtained by conizations. HPV-16 DNA was detected only in the sections that contained CIN lesions and/or koilocytes. No HPV-16 DNA was detected in sections that contained only normal epithelium. This is in accordance with HPV-16 playing a role in the development of CIN lesions",

author = "Cornelissen, \{M. T.\} and \{van den Tweel\}, \{J. G.\} and Struyk, \{A. P.\} and Jebbink, \{M. F.\} and M. Bri{\"e}t and \{van der Noordaa\}, J. and \{ter Schegget\}, \{J. T.\}",

year = "1989",

doi = "10.1099/0022-1317-70-10-2555",

language = "English",

volume = "70",

pages = "2555--2562",

journal = "Journal of general virology",

issn = "0022-1317",

publisher = "Society for General Microbiology",

number = "10",

}

Cornelissen, MT, van den Tweel, JG, Struyk, AP, Jebbink, MF, Briët, M, van der Noordaa, J & ter Schegget, JT 1989, 'LOCALIZATION OF HUMAN PAPILLOMAVIRUS TYPE-16 DNA USING THE POLYMERASE CHAIN-REACTION IN THE CERVIX UTERI OF WOMEN WITH CERVICAL INTRAEPITHELIAL NEOPLASIA', Journal of general virology, vol. 70, no. 10, pp. 2555-2562. https://doi.org/10.1099/0022-1317-70-10-2555

LOCALIZATION OF HUMAN PAPILLOMAVIRUS TYPE-16 DNA USING THE POLYMERASE CHAIN-REACTION IN THE CERVIX UTERI OF WOMEN WITH CERVICAL INTRAEPITHELIAL NEOPLASIA. / Cornelissen, M. T.; van den Tweel, J. G.; Struyk, A. P. et al.
In: Journal of general virology, Vol. 70, No. 10, 1989, p. 2555-2562.

Research output: Contribution to journal › Article › Academic › peer-review

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T1 - LOCALIZATION OF HUMAN PAPILLOMAVIRUS TYPE-16 DNA USING THE POLYMERASE CHAIN-REACTION IN THE CERVIX UTERI OF WOMEN WITH CERVICAL INTRAEPITHELIAL NEOPLASIA

AU - Cornelissen, M. T.

AU - van den Tweel, J. G.

AU - Struyk, A. P.

AU - Jebbink, M. F.

AU - Briët, M.

AU - van der Noordaa, J.

AU - ter Schegget, J. T.

PY - 1989

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AB - The localization of human papillomavirus type 16 (HPV-16) DNA throughout the cervix uteri of women with cervical intraepithelial neoplasia (CIN) was studied by utilizing the polymerase chain reaction technique directly on histologically defined sections of paraffin-embedded cervical tissue obtained by conizations. HPV-16 DNA was detected only in the sections that contained CIN lesions and/or koilocytes. No HPV-16 DNA was detected in sections that contained only normal epithelium. This is in accordance with HPV-16 playing a role in the development of CIN lesions

U2 - 10.1099/0022-1317-70-10-2555

DO - 10.1099/0022-1317-70-10-2555

M3 - Article

C2 - 2552002

SN - 0022-1317

VL - 70

SP - 2555

EP - 2562

JO - Journal of general virology

JF - Journal of general virology

IS - 10

ER -

LOCALIZATION OF HUMAN PAPILLOMAVIRUS TYPE-16 DNA USING THE POLYMERASE CHAIN-REACTION IN THE CERVIX UTERI OF WOMEN WITH CERVICAL INTRAEPITHELIAL NEOPLASIA

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