International expert panel’s potentially inappropriate prescribing cascades (PIPC) list

Paula A. Rochon; Denis O’Mahony; Antonio Cherubini; Graziano Onder; Mirko Petrovic; Kieran Dalton; Lisa M. McCarthy; Shelley A. Sternberg; Donna R. Zwas; Nathan M. Stall; Christina E. Reppas-Rindlisbacher; Nathalie van der Velde; Sarah N. Hilmer; Wei Wu; Joyce Li; Amy Ly; Jerry H. Gurwitz

doi:10.1007/s41999-025-01215-x

International expert panel’s potentially inappropriate prescribing cascades (PIPC) list

Paula A. Rochon^*
, Denis O’Mahony
, Antonio Cherubini
, Graziano Onder
, Mirko Petrovic
, Kieran Dalton
, Lisa M. McCarthy
, Shelley A. Sternberg
, Donna R. Zwas
, Nathan M. Stall
, Christina E. Reppas-Rindlisbacher
, Nathalie van der Velde
, Sarah N. Hilmer
, Wei Wu
, Joyce Li
, Amy Ly
, Jerry H. Gurwitz

^*Corresponding author for this work

University of Toronto
Institute for Clinical Evaluative Sciences
Sinai Health
University College Cork
Marche Polytechnic University
Istituto Nazionale di Riposo e Cura per Anziani - Ancona
Catholic University of the Sacred Heart
Alcohol Use Disorder and Alcohol Related Disease Unit, Department of Internal Medicine and Gastroenterology, Fondazione Policlinico Universitario A. Gemelli IRCCS
Ghent University
Trillium Health Partners
Maccabi Healthcare Services
Hebrew University of Jerusalem
University of Amsterdam
Amsterdam UMC
Royal North Shore Hospital
Kolling Institute of Medical Research
University of Massachusetts Medical School

Research output: Contribution to journal › Article › Academic › peer-review

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Abstract

Aim: To create a list of potentially inappropriate prescribing cascades (PIPCs) that should be considered when reviewing a patient’s medications. Findings: Through a modified Delphi process, an international expert panel reached consensus on 65 potentially inappropriate prescribing cascades to be included in the final PIPC list. Message: This PIPC list can assist in identifying potentially inappropriate prescribing cascades and help to foster medication safety in older adults.

Original language	English
Pages (from-to)	1573-1584
Number of pages	12
Journal	European geriatric medicine
Volume	16
Issue number	5
Early online date	2025
DOIs	https://doi.org/10.1007/s41999-025-01215-x
Publication status	Published - Oct 2025

Keywords

Delphi consensus
Older adults
Optimizing drug therapy
Prescribing cascade

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International-expert-panels-potentially-inappropriate-prescribing-cascades-pipc-list.pdfFinal published version, 1.07 MBLicence: Taverne

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Rochon, P. A., O’Mahony, D., Cherubini, A., Onder, G., Petrovic, M., Dalton, K., McCarthy, L. M., Sternberg, S. A., Zwas, D. R., Stall, N. M., Reppas-Rindlisbacher, C. E., van der Velde, N., Hilmer, S. N., Wu, W., Li, J., Ly, A., & Gurwitz, J. H. (2025). International expert panel’s potentially inappropriate prescribing cascades (PIPC) list. European geriatric medicine, 16(5), 1573-1584. https://doi.org/10.1007/s41999-025-01215-x

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title = "International expert panel{\textquoteright}s potentially inappropriate prescribing cascades (PIPC) list",

abstract = "Aim: To create a list of potentially inappropriate prescribing cascades (PIPCs) that should be considered when reviewing a patient{\textquoteright}s medications. Findings: Through a modified Delphi process, an international expert panel reached consensus on 65 potentially inappropriate prescribing cascades to be included in the final PIPC list. Message: This PIPC list can assist in identifying potentially inappropriate prescribing cascades and help to foster medication safety in older adults.",

keywords = "Delphi consensus, Older adults, Optimizing drug therapy, Prescribing cascade",

author = "Rochon, \{Paula A.\} and Denis O{\textquoteright}Mahony and Antonio Cherubini and Graziano Onder and Mirko Petrovic and Kieran Dalton and McCarthy, \{Lisa M.\} and Sternberg, \{Shelley A.\} and Zwas, \{Donna R.\} and Stall, \{Nathan M.\} and Reppas-Rindlisbacher, \{Christina E.\} and \{van der Velde\}, Nathalie and Hilmer, \{Sarah N.\} and Wei Wu and Joyce Li and Amy Ly and Gurwitz, \{Jerry H.\}",

note = "Publisher Copyright: {\textcopyright} The Author(s), under exclusive licence to European Geriatric Medicine Society 2025.",

year = "2025",

month = oct,

doi = "10.1007/s41999-025-01215-x",

language = "English",

volume = "16",

pages = "1573--1584",

journal = "European geriatric medicine",

issn = "1878-7649",

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Rochon, PA, O’Mahony, D, Cherubini, A, Onder, G, Petrovic, M, Dalton, K, McCarthy, LM, Sternberg, SA, Zwas, DR, Stall, NM, Reppas-Rindlisbacher, CE, van der Velde, N, Hilmer, SN, Wu, W, Li, J, Ly, A & Gurwitz, JH 2025, 'International expert panel’s potentially inappropriate prescribing cascades (PIPC) list', European geriatric medicine, vol. 16, no. 5, pp. 1573-1584. https://doi.org/10.1007/s41999-025-01215-x

TY - JOUR

T1 - International expert panel’s potentially inappropriate prescribing cascades (PIPC) list

AU - Rochon, Paula A.

AU - O’Mahony, Denis

AU - Cherubini, Antonio

AU - Onder, Graziano

AU - Petrovic, Mirko

AU - Dalton, Kieran

AU - McCarthy, Lisa M.

AU - Sternberg, Shelley A.

AU - Zwas, Donna R.

AU - Stall, Nathan M.

AU - Reppas-Rindlisbacher, Christina E.

AU - van der Velde, Nathalie

AU - Hilmer, Sarah N.

AU - Wu, Wei

AU - Li, Joyce

AU - Ly, Amy

AU - Gurwitz, Jerry H.

PY - 2025/10

Y1 - 2025/10

N2 - Aim: To create a list of potentially inappropriate prescribing cascades (PIPCs) that should be considered when reviewing a patient’s medications. Findings: Through a modified Delphi process, an international expert panel reached consensus on 65 potentially inappropriate prescribing cascades to be included in the final PIPC list. Message: This PIPC list can assist in identifying potentially inappropriate prescribing cascades and help to foster medication safety in older adults.

AB - Aim: To create a list of potentially inappropriate prescribing cascades (PIPCs) that should be considered when reviewing a patient’s medications. Findings: Through a modified Delphi process, an international expert panel reached consensus on 65 potentially inappropriate prescribing cascades to be included in the final PIPC list. Message: This PIPC list can assist in identifying potentially inappropriate prescribing cascades and help to foster medication safety in older adults.

KW - Delphi consensus

KW - Older adults

KW - Optimizing drug therapy

KW - Prescribing cascade

UR - https://www.scopus.com/pages/publications/105012272626

U2 - 10.1007/s41999-025-01215-x

DO - 10.1007/s41999-025-01215-x

M3 - Article

C2 - 40742670

SN - 1878-7649

VL - 16

SP - 1573

EP - 1584

JO - European geriatric medicine

JF - European geriatric medicine

IS - 5

ER -

International expert panel’s potentially inappropriate prescribing cascades (PIPC) list

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