Inhibition of TGF beta signaling decreases osteogenic differentiation of fibrodysplasia ossificans progressiva fibroblasts in a novel in vitro model of the disease

Dimitra Micha; Elise Voermans; Marelise E. W. Eekhoff; Huib W. van Essen; Behrouz Zandieh-Doulabi; Coen Netelenbos; Thomas Rustemeyer; E. A. Sistermans; Gerard Pals; Nathalie Bravenboer

doi:10.1016/j.bone.2016.01.004

Inhibition of TGF beta signaling decreases osteogenic differentiation of fibrodysplasia ossificans progressiva fibroblasts in a novel in vitro model of the disease

Research output: Contribution to journal › Article › Academic › peer-review

Original language	English
Pages (from-to)	169-180
Journal	Bone
Volume	84
DOIs	https://doi.org/10.1016/j.bone.2016.01.004
Publication status	Published - Mar 2016

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Fibrodyplasia ossificans progressiva
Transforming growth factor beta
Fibroblast
Osteogenic differentiation
Inflammation
Ossification

Access to Document

10.1016/j.bone.2016.01.004

Cite this

Micha, D., Voermans, E., Eekhoff, M. E. W., van Essen, H. W., Zandieh-Doulabi, B., Netelenbos, C., Rustemeyer, T., Sistermans, E. A., Pals, G., & Bravenboer, N. (2016). Inhibition of TGF beta signaling decreases osteogenic differentiation of fibrodysplasia ossificans progressiva fibroblasts in a novel in vitro model of the disease. Bone, 84, 169-180. https://doi.org/10.1016/j.bone.2016.01.004

@article{c440d9cb8c8b4fe18bb1e981e1600721,

title = "Inhibition of TGF beta signaling decreases osteogenic differentiation of fibrodysplasia ossificans progressiva fibroblasts in a novel in vitro model of the disease",

keywords = "Fibrodyplasia ossificans progressiva, Transforming growth factor beta, Fibroblast, Osteogenic differentiation, Inflammation, Ossification",

author = "Dimitra Micha and Elise Voermans and Eekhoff, \{Marelise E. W.\} and \{van Essen\}, \{Huib W.\} and Behrouz Zandieh-Doulabi and Coen Netelenbos and Thomas Rustemeyer and Sistermans, \{E. A.\} and Gerard Pals and Nathalie Bravenboer",

year = "2016",

month = mar,

doi = "10.1016/j.bone.2016.01.004",

language = "English",

volume = "84",

pages = "169--180",

journal = "Bone",

issn = "8756-3282",

publisher = "Elsevier Inc.",

}

Micha, D, Voermans, E, Eekhoff, MEW , van Essen, HW, Zandieh-Doulabi, B, Netelenbos, C , Rustemeyer, T , Sistermans, EA , Pals, G & Bravenboer, N 2016, 'Inhibition of TGF beta signaling decreases osteogenic differentiation of fibrodysplasia ossificans progressiva fibroblasts in a novel in vitro model of the disease', Bone, vol. 84, pp. 169-180. https://doi.org/10.1016/j.bone.2016.01.004

TY - JOUR

T1 - Inhibition of TGF beta signaling decreases osteogenic differentiation of fibrodysplasia ossificans progressiva fibroblasts in a novel in vitro model of the disease

AU - Micha, Dimitra

AU - Voermans, Elise

AU - Eekhoff, Marelise E. W.

AU - van Essen, Huib W.

AU - Zandieh-Doulabi, Behrouz

AU - Netelenbos, Coen

AU - Rustemeyer, Thomas

AU - Sistermans, E. A.

AU - Pals, Gerard

AU - Bravenboer, Nathalie

PY - 2016/3

Y1 - 2016/3

KW - Fibrodyplasia ossificans progressiva

KW - Transforming growth factor beta

KW - Fibroblast

KW - Osteogenic differentiation

KW - Inflammation

KW - Ossification

U2 - 10.1016/j.bone.2016.01.004

DO - 10.1016/j.bone.2016.01.004

M3 - Article

C2 - 26769004

SN - 8756-3282

VL - 84

SP - 169

EP - 180

JO - Bone

JF - Bone

ER -