Abstract
Thrombophilia can be defined as laboratory abnormalities, usually in the coagulation system, that result in a hypercoagulable state and thus predispose to thrombosis. These abnormalities may be acquired or inherited. The most clearly established form of acquired thrombophilia is the antiphospholipid anti- body syndrome. This chapter focuses on inherited thrombophilia. The relevance of inherited thrombophilia in early pregnancy is manifested in an elevated risk of venous thromboembolism, a modestly increased risk of miscarriage, and a possible relation with fertility.
| Original language | English |
|---|---|
| Title of host publication | Early Pregnancy, Third Edition |
| Publisher | Cambridge University Press |
| Pages | 122-136 |
| Number of pages | 15 |
| ISBN (Electronic) | 9781009532549 |
| ISBN (Print) | 9781009532501 |
| DOIs | |
| Publication status | Published - 1 Jan 2025 |
| Externally published | Yes |
Publication series
| Name | Early Pregnancy, Third Edition |
|---|
UN SDGs
This output contributes to the following UN Sustainable Development Goals (SDGs)
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SDG 3 Good Health and Well-being
Keywords
- Acetylsalicylic acid
- Anticoagulants
- Antithrombin deficiency
- Factor V Leiden
- Low-molecular-weight heparin
- Protein C deficiency
- Protein S deficiency
- Prothrombin G20210A mutation
- Thrombophilia
- Venous thromboembolism
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