Incidentie van darmkanker stijgt bij jonge mensen in Nederland

Marloes A. G. Elferink; Laskarina J. K. Galanos; Femke P. C. Sijtsma; Maarten J. Bijlsma; Tineke E. Buffart; Ignace H. J. T. de Hingh; Monique E. van Leerdam; Felice N. van Erning

Incidentie van darmkanker stijgt bij jonge mensen in Nederland

Translated title of the contribution: Rise in incidence of early-onset colorectal cancer in the Netherlands: cause for concern?

Marloes A. G. Elferink
, Laskarina J. K. Galanos
, Femke P. C. Sijtsma
, Maarten J. Bijlsma
, Tineke E. Buffart
, Ignace H. J. T. de Hingh
, Monique E. van Leerdam
, Felice N. van Erning

Research output: Contribution to journal › Article › Professional

Abstract

OBJECTIVE: To describe trends in incidence of early-onset colorectal cancer in the Netherlands. DESIGN: Observational research. METHOD: We selected colorectal cancer patients aged 15 to 49 years, diagnosed between 1989-2023, from the Netherlands Cancer Registry (NCR). We calculated incidence rates and determined changes in trends using Joinpoint regression analyses. Furthermore, we made a prediction of the number of early-onset colorectal cancer patients in 2035. RESULTS: The number of new early-onset colorectal cancer patients has increased; from 6.3 per 100,000 in 1998 to 9.3 per 100,000 in 2023 (Annual Percentage Change 1.41% (95% confidence interval 1.18-1.71)). This incidence is expected to increase further in the future, reaching between 629 and 871 cases by 2035. CONCLUSION: There is an increase in the incidence of early-onset colorectal cancer in the Netherlands which appears to persist over the next 10 years. Further research is needed to identify the causes of this increase.

Translated title of the contribution	Rise in incidence of early-onset colorectal cancer in the Netherlands: cause for concern?
Original language	Dutch
Journal	Nederlands tijdschrift voor geneeskunde
Volume	169
Publication status	Published - 24 Apr 2025

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This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Cite this

@article{4197307165414532a163b67b0e5f88b2,

title = "Incidentie van darmkanker stijgt bij jonge mensen in Nederland",

abstract = "OBJECTIVE: To describe trends in incidence of early-onset colorectal cancer in the Netherlands. DESIGN: Observational research. METHOD: We selected colorectal cancer patients aged 15 to 49 years, diagnosed between 1989-2023, from the Netherlands Cancer Registry (NCR). We calculated incidence rates and determined changes in trends using Joinpoint regression analyses. Furthermore, we made a prediction of the number of early-onset colorectal cancer patients in 2035. RESULTS: The number of new early-onset colorectal cancer patients has increased; from 6.3 per 100,000 in 1998 to 9.3 per 100,000 in 2023 (Annual Percentage Change 1.41\% (95\% confidence interval 1.18-1.71)). This incidence is expected to increase further in the future, reaching between 629 and 871 cases by 2035. CONCLUSION: There is an increase in the incidence of early-onset colorectal cancer in the Netherlands which appears to persist over the next 10 years. Further research is needed to identify the causes of this increase.",

author = "Elferink, \{Marloes A. G.\} and Galanos, \{Laskarina J. K.\} and Sijtsma, \{Femke P. C.\} and Bijlsma, \{Maarten J.\} and Buffart, \{Tineke E.\} and \{de Hingh\}, \{Ignace H. J. T.\} and \{van Leerdam\}, \{Monique E.\} and \{van Erning\}, \{Felice N.\}",

year = "2025",

month = apr,

day = "24",

language = "Dutch",

volume = "169",

journal = "Nederlands tijdschrift voor geneeskunde",

issn = "0028-2162",

publisher = "Bohn Stafleu Van Loghum",

}

TY - JOUR

T1 - Incidentie van darmkanker stijgt bij jonge mensen in Nederland

AU - Elferink, Marloes A. G.

AU - Galanos, Laskarina J. K.

AU - Sijtsma, Femke P. C.

AU - Bijlsma, Maarten J.

AU - Buffart, Tineke E.

AU - de Hingh, Ignace H. J. T.

AU - van Leerdam, Monique E.

AU - van Erning, Felice N.

PY - 2025/4/24

Y1 - 2025/4/24

N2 - OBJECTIVE: To describe trends in incidence of early-onset colorectal cancer in the Netherlands. DESIGN: Observational research. METHOD: We selected colorectal cancer patients aged 15 to 49 years, diagnosed between 1989-2023, from the Netherlands Cancer Registry (NCR). We calculated incidence rates and determined changes in trends using Joinpoint regression analyses. Furthermore, we made a prediction of the number of early-onset colorectal cancer patients in 2035. RESULTS: The number of new early-onset colorectal cancer patients has increased; from 6.3 per 100,000 in 1998 to 9.3 per 100,000 in 2023 (Annual Percentage Change 1.41% (95% confidence interval 1.18-1.71)). This incidence is expected to increase further in the future, reaching between 629 and 871 cases by 2035. CONCLUSION: There is an increase in the incidence of early-onset colorectal cancer in the Netherlands which appears to persist over the next 10 years. Further research is needed to identify the causes of this increase.

AB - OBJECTIVE: To describe trends in incidence of early-onset colorectal cancer in the Netherlands. DESIGN: Observational research. METHOD: We selected colorectal cancer patients aged 15 to 49 years, diagnosed between 1989-2023, from the Netherlands Cancer Registry (NCR). We calculated incidence rates and determined changes in trends using Joinpoint regression analyses. Furthermore, we made a prediction of the number of early-onset colorectal cancer patients in 2035. RESULTS: The number of new early-onset colorectal cancer patients has increased; from 6.3 per 100,000 in 1998 to 9.3 per 100,000 in 2023 (Annual Percentage Change 1.41% (95% confidence interval 1.18-1.71)). This incidence is expected to increase further in the future, reaching between 629 and 871 cases by 2035. CONCLUSION: There is an increase in the incidence of early-onset colorectal cancer in the Netherlands which appears to persist over the next 10 years. Further research is needed to identify the causes of this increase.

UR - https://www.scopus.com/pages/publications/105004481424

M3 - Article

C2 - 40310280

SN - 0028-2162

VL - 169

JO - Nederlands tijdschrift voor geneeskunde

JF - Nederlands tijdschrift voor geneeskunde

ER -

Incidentie van darmkanker stijgt bij jonge mensen in Nederland

Abstract

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