Incident cancer risk after the start of aspirin use: results from a Dutch population-based cohort study of low dose aspirin users

L. M. Hollestein; M. P. van Herk-Sukel; R. Ruiter; E. de Vries; R. H. Mathijssen; E. A. Wiemer; T. Stijnen; J. W. Coebergh; V. E. Lemmens; R. M. Herings; B. H. Stricker; T. Nijsten

doi:10.1002/ijc.28634

Incident cancer risk after the start of aspirin use: results from a Dutch population-based cohort study of low dose aspirin users

L. M. Hollestein
, M. P. van Herk-Sukel
, R. Ruiter
, E. de Vries
, R. H. Mathijssen
, E. A. Wiemer
, T. Stijnen
, J. W. Coebergh
, V. E. Lemmens
, R. M. Herings
, B. H. Stricker
, T. Nijsten

PHARMO Instituut

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

Observational and intervention studies suggest that low dose aspirin use may prevent cancer. The objective of this study was to investigate the protective effect of long term low dose aspirin use (6 years aspirin use compared to 6 years aspirin use 0.95, 95% CI 0.60-1.49). Our results do not support the primary prevention of cancer among long term aspirin users.

Original language	English
Pages (from-to)	157-165
Number of pages	9
Journal	International Journal of Cancer
Volume	135
Issue number	1
DOIs	https://doi.org/10.1002/ijc.28634
Publication status	Published - 2014
Externally published	Yes

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Adult Aged Anti-Inflammatory Agents, Non-Steroidal/*therapeutic use Aspirin/*therapeutic use Cohort Studies Dose-Response Relationship, Drug Female Humans Male Middle Aged Neoplasms/*drug therapy/epidemiology/pathology Proportional Hazards Models Risk Factors aspirin cancer chemoprevention epidemiology population-based

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10.1002/ijc.28634

https://www.ncbi.nlm.nih.gov/pubmed/24285345

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Hollestein, L. M., van Herk-Sukel, M. P., Ruiter, R., de Vries, E., Mathijssen, R. H., Wiemer, E. A., Stijnen, T., Coebergh, J. W., Lemmens, V. E., Herings, R. M., Stricker, B. H., & Nijsten, T. (2014). Incident cancer risk after the start of aspirin use: results from a Dutch population-based cohort study of low dose aspirin users. International Journal of Cancer, 135(1), 157-165. https://doi.org/10.1002/ijc.28634

@article{130026d16a31403094a0428bdee83ef8,

title = "Incident cancer risk after the start of aspirin use: results from a Dutch population-based cohort study of low dose aspirin users",

abstract = "Observational and intervention studies suggest that low dose aspirin use may prevent cancer. The objective of this study was to investigate the protective effect of long term low dose aspirin use (6 years aspirin use compared to 6 years aspirin use 0.95, 95\% CI 0.60-1.49). Our results do not support the primary prevention of cancer among long term aspirin users.",

keywords = "Adult Aged Anti-Inflammatory Agents, Non-Steroidal/*therapeutic use Aspirin/*therapeutic use Cohort Studies Dose-Response Relationship, Drug Female Humans Male Middle Aged Neoplasms/*drug therapy/epidemiology/pathology Proportional Hazards Models Risk Factors aspirin cancer chemoprevention epidemiology population-based",

author = "Hollestein, \{L. M.\} and \{van Herk-Sukel\}, \{M. P.\} and R. Ruiter and \{de Vries\}, E. and Mathijssen, \{R. H.\} and Wiemer, \{E. A.\} and T. Stijnen and Coebergh, \{J. W.\} and Lemmens, \{V. E.\} and Herings, \{R. M.\} and Stricker, \{B. H.\} and T. Nijsten",

note = "Hollestein, Loes M van Herk-Sukel, Myrthe P P Ruiter, Rikje de Vries, Esther Mathijssen, Ron H J Wiemer, Erik A C Stijnen, Theo Coebergh, Jan-Willem W Lemmens, Valery E P P Herings, Ron M C Stricker, Bruno H C Nijsten, Tamar eng Int J Cancer. 2014 Jul 1;135(1):157-65. doi: 10.1002/ijc.28634. Epub 2013 Dec 9.",

year = "2014",

doi = "10.1002/ijc.28634",

language = "English",

volume = "135",

pages = "157--165",

journal = "International Journal of Cancer",

issn = "0020-7136",

publisher = "Wiley-Liss Inc.",

number = "1",

}

Hollestein, LM, van Herk-Sukel, MP, Ruiter, R, de Vries, E, Mathijssen, RH, Wiemer, EA, Stijnen, T, Coebergh, JW, Lemmens, VE, Herings, RM, Stricker, BH & Nijsten, T 2014, 'Incident cancer risk after the start of aspirin use: results from a Dutch population-based cohort study of low dose aspirin users', International Journal of Cancer, vol. 135, no. 1, pp. 157-165. https://doi.org/10.1002/ijc.28634

TY - JOUR

T1 - Incident cancer risk after the start of aspirin use: results from a Dutch population-based cohort study of low dose aspirin users

AU - Hollestein, L. M.

AU - van Herk-Sukel, M. P.

AU - Ruiter, R.

AU - de Vries, E.

AU - Mathijssen, R. H.

AU - Wiemer, E. A.

AU - Stijnen, T.

AU - Coebergh, J. W.

AU - Lemmens, V. E.

AU - Herings, R. M.

AU - Stricker, B. H.

AU - Nijsten, T.

N1 - Hollestein, Loes M van Herk-Sukel, Myrthe P P Ruiter, Rikje de Vries, Esther Mathijssen, Ron H J Wiemer, Erik A C Stijnen, Theo Coebergh, Jan-Willem W Lemmens, Valery E P P Herings, Ron M C Stricker, Bruno H C Nijsten, Tamar eng Int J Cancer. 2014 Jul 1;135(1):157-65. doi: 10.1002/ijc.28634. Epub 2013 Dec 9.

PY - 2014

Y1 - 2014

N2 - Observational and intervention studies suggest that low dose aspirin use may prevent cancer. The objective of this study was to investigate the protective effect of long term low dose aspirin use (6 years aspirin use compared to 6 years aspirin use 0.95, 95% CI 0.60-1.49). Our results do not support the primary prevention of cancer among long term aspirin users.

AB - Observational and intervention studies suggest that low dose aspirin use may prevent cancer. The objective of this study was to investigate the protective effect of long term low dose aspirin use (6 years aspirin use compared to 6 years aspirin use 0.95, 95% CI 0.60-1.49). Our results do not support the primary prevention of cancer among long term aspirin users.

KW - Adult Aged Anti-Inflammatory Agents, Non-Steroidal/therapeutic use Aspirin/therapeutic use Cohort Studies Dose-Response Relationship, Drug Female Humans Male Middle Aged Neoplasms/drug therapy/epidemiology/pathology Proportional Hazards Models Risk Factor

U2 - 10.1002/ijc.28634

DO - 10.1002/ijc.28634

M3 - Article

SN - 0020-7136

VL - 135

SP - 157

EP - 165

JO - International Journal of Cancer

JF - International Journal of Cancer

IS - 1

ER -

Incident cancer risk after the start of aspirin use: results from a Dutch population-based cohort study of low dose aspirin users

Abstract

UN SDGs

Keywords

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