In vitro killing of Mycobacterium ulcerans by acidified nitrite

R. Phillips; S. Kuijper; N. Benjamin; M. Wansbrough-Jones; M. Wilks; A. H. J. Kolk

doi:10.1128/AAC.48.8.3130-3132.2004

In vitro killing of Mycobacterium ulcerans by acidified nitrite

R. Phillips^*
, S. Kuijper
, N. Benjamin
, M. Wansbrough-Jones
, M. Wilks
, A. H. J. Kolk

^*Corresponding author for this work

Komfo Anokye Teaching Hospital
Royal Tropical Institute
St. George's University of London
Peninsula Medical School Universities of Exeter and Plymouth
Cardiac Imaging Department, Barts Heart Centre, London, UK

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

Mycobacterium ulcerans, which causes Buruli ulcer, was exposed to acidified nitrite or to acid alone for 10 or 20 min. Killing was rapid, and viable counts were reduced below detectable limits within 10 min of exposure to 40 mM acidified nitrite. M. ulcerans is highly susceptible to acidified nitrite in vitro.

Original language	English
Pages (from-to)	3130-3132
Journal	Antimicrobial agents and chemotherapy
Volume	48
Issue number	8
DOIs	https://doi.org/10.1128/AAC.48.8.3130-3132.2004
Publication status	Published - Aug 2004
Externally published	Yes

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10.1128/AAC.48.8.3130-3132.2004

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title = "In vitro killing of Mycobacterium ulcerans by acidified nitrite",

abstract = "Mycobacterium ulcerans, which causes Buruli ulcer, was exposed to acidified nitrite or to acid alone for 10 or 20 min. Killing was rapid, and viable counts were reduced below detectable limits within 10 min of exposure to 40 mM acidified nitrite. M. ulcerans is highly susceptible to acidified nitrite in vitro.",

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AU - Kuijper, S.

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AU - Wansbrough-Jones, M.

AU - Wilks, M.

AU - Kolk, A. H. J.

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AB - Mycobacterium ulcerans, which causes Buruli ulcer, was exposed to acidified nitrite or to acid alone for 10 or 20 min. Killing was rapid, and viable counts were reduced below detectable limits within 10 min of exposure to 40 mM acidified nitrite. M. ulcerans is highly susceptible to acidified nitrite in vitro.

UR - https://www.scopus.com/pages/publications/3342880789

UR - https://www.ncbi.nlm.nih.gov/pubmed/15273132

U2 - 10.1128/AAC.48.8.3130-3132.2004

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SP - 3130

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JO - Antimicrobial agents and chemotherapy

JF - Antimicrobial agents and chemotherapy

IS - 8

ER -

In vitro killing of Mycobacterium ulcerans by acidified nitrite

Abstract

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