Improving antibiotic therapy in critically ill patients through pharmacokinetic dose optimization

C.J. Hodiamont

Improving antibiotic therapy in critically ill patients through pharmacokinetic dose optimization

C.J. Hodiamont

Research output: PhD Thesis › Phd-Thesis - Research and graduation internal

Abstract

Each year, thousands of critically ill patients admitted to Dutch intensive care units suffer from severe bacterial infections. Early and adequate antibiotic treatment significantly lowers the mortality of these infections. The efficacy and safety of antibiotics like gentamicin, vancomycin and ceftazidime depends on the concentrations that are achieved in serum and in infected body tissues.

Original language	English
Qualification	Doctor of Philosophy
Awarding Institution	University of Amsterdam
Supervisors/Advisors	Mathot, Ron, Supervisor de Jong, Menno, Supervisor Juffermans, Nicole, Co-supervisor van Hest, Reinier, Co-supervisor
Award date	1 Dec 2023
Print ISBNs	9789464832495
Publication status	Published - 2023

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https://hdl.handle.net/11245.1/241d77ff-8049-4cdd-baa3-c475a24a418c

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title = "Improving antibiotic therapy in critically ill patients through pharmacokinetic dose optimization",

abstract = "Each year, thousands of critically ill patients admitted to Dutch intensive care units suffer from severe bacterial infections. Early and adequate antibiotic treatment significantly lowers the mortality of these infections. The efficacy and safety of antibiotics like gentamicin, vancomycin and ceftazidime depends on the concentrations that are achieved in serum and in infected body tissues.",

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AB - Each year, thousands of critically ill patients admitted to Dutch intensive care units suffer from severe bacterial infections. Early and adequate antibiotic treatment significantly lowers the mortality of these infections. The efficacy and safety of antibiotics like gentamicin, vancomycin and ceftazidime depends on the concentrations that are achieved in serum and in infected body tissues.

M3 - Phd-Thesis - Research and graduation internal

SN - 9789464832495

ER -

Improving antibiotic therapy in critically ill patients through pharmacokinetic dose optimization

Abstract

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